CoVaTrack: COVID-19 Vaccine & Treatment Tracker for India

Status	Trial
Confirmed	3093
Confirmed Or Healthy	30
Confirmed Or Suspected	197
Confirmed, Suspected Or Healthy	7
Healthy	445
NA	685
Resolved	32
Resolved Or Healthy	1
Suspected	36
Suspected Or Healthy	3
Unclear	10
Final	4539

Stage	Development %	Frequency
Regulatory Review	0.02	4
Authorized	0.15	29
Pre-clinical	54.41	10873
Clinical	38.54	7702
Phase I	2.29	458
Phase I/II	2.3	460
Phase II	0.56	111
Phase II/III	0.11	22
Phase III	1.62	323

Developer	Researcher	Vaccine Candidate	Phase
Bharat Biotech International Limited	ICMR - National Institute of Virology, Pune	CTRI/2020/07/026300	Phase I / Phase II
Cadila Healthcare Ltd.	Cadila Healthcare Ltd.	CTRI/2020/07/026352	Phase I / Phase II
Cadila Pharmaceuticals Ltd.	CSIR	CTRI/2020/04/024846	Phase III
Green Signal Biopharma Ltd.	JIPMER	CTRI/2020/04/024833	N/A
Haffkine Institute for Training Research & Testing	Haffkine Institute for Training Research & Testing	CTRI/2020/05/025013	Phase II
Indian Immunologicals Limited	Griffith University, Australia	Pre-Clinical	N/A
Mynvax	Indian Institute of Science (Bengaluru)	Pre-Clinical	N/A
Panacea Biotec Limited	Refana Inc, US	Pre-Clinical	N/A
Serum Institute of India	National Institute for Research in Tuberculosis	CTRI/2020/06/025854	N/A
Serum institute of India & AstraZeneca	University of Oxford	CTRI/2020/04/024749	Phase III

Abu Dhabi

COVID-19 status

Confirmed
Outcome

Mortality, Serious Adverse Events
Treatment

Plasma based therapy, SOC
Trial Participants

80

Abu Dhabi

COVID-19 status

Healthy
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

45000

Abu Dhabi

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any)
Treatment

SOC, Stem cells
Trial Participants

146

Abu Dhabi

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ + AZT, SOC
Trial Participants

4000

Accra

COVID-19 status

Confirmed Or Healthy
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious or Seconday Infections, Serious Adverse Events, ALT
Treatment

HCQ, LPV/r, SOC
Trial Participants

6400

Accra

COVID-19 status

Confirmed Or Healthy
Outcome

Mortality, Hospital Discharge, Pneumonia or ARDS, Distress
Treatment

HCQ, HCQ + LPV/r, LPV/r, SOC
Trial Participants

6400

Accra

COVID-19 status

Healthy
Outcome

Mortality, Pneumonia or ARDS, Distress
Treatment

HCQ, HCQ + LPV/r, LPV/r, SOC
Trial Participants

6400

Accra

COVID-19 status

Confirmed
Outcome

Mortality, SpO2
Treatment

HCQ, LPV/r, SOC
Trial Participants

3000

Adana

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Serious Adverse Events, IgG, IgM or IgA, Antibodies
Treatment

SOC, Vaccine
Trial Participants

13000

Addis Ababa

COVID-19 status

Confirmed
Outcome

Mortality, SpO2
Treatment

HCQ, LPV/r, SOC
Trial Participants

3000

Afyonkarahisar

COVID-19 status

Confirmed
Outcome

Mortality, Fever, Adverse Events, Ferritin, Lymphocyte Count, D-Dimer, Heart Rate, PaO2-FiO2, SpO2, Respiratory Rate, Radiographic Findings
Treatment

Ivermectin, SOC
Trial Participants

60

Aguascalientes

COVID-19 status

Confirmed
Outcome

Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ + Ivermectin, Ivermectin
Trial Participants

108

Aichi

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance
Treatment

FPV, SOC
Trial Participants

86

Aichi

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Aichi

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO
Treatment

FPV + Corticosteroids
Trial Participants

69

Al Iskandariyah

COVID-19 status

Confirmed
Outcome

NA
Treatment

Imatinib, SOC
Trial Participants

30

Al Madinah

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Adverse Events
Treatment

FPV, SOC
Trial Participants

576

Alabama

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Serious Adverse Events, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Plasma based therapy, SOC
Trial Participants

702

Alabama

COVID-19 status

NA
Outcome

Viral Load or Clearance
Treatment

DHODH inhibitor, SOC
Trial Participants

100

Alabama

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, Remdesivir + JAKi
Trial Participants

1034

Alabama

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB
Trial Participants

2970

Alabama

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, PaO2-FiO2
Treatment

Acalabrutinib, SOC
Trial Participants

61

Alabama

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Alabama

COVID-19 status

Confirmed
Outcome

NA
Treatment

Non-invasive respiratory support, SOC
Trial Participants

200

Alabama

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Other Mild Symptoms
Treatment

NA
Trial Participants

60

Alabama

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, Ferritin, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Troponin, Fibrinogen, INR, ALT, AST, Albumin, Bilirubin, Glucose, LDH, IgG, IgM or IgA, Blood Urea Nitrogen, Blood Pressure, SpO2, Radiographic Findings
Treatment

Plasma based therapy, SOC
Trial Participants

208

Alabama

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Fever, Adverse Events, Antibodies, SpO2
Treatment

Other, SOC
Trial Participants

2000

Alabama

COVID-19 status

Confirmed
Outcome

Fever, Serious Adverse Events, Platelet Count, ALT, AST, Albumin, Bilirubin, Blood Pressure, Heart Rate, SpO2
Treatment

Other, SOC
Trial Participants

300

Alabama

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA)
Treatment

mAb, SOC
Trial Participants

390

Alabama

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, ECG, SpO2
Treatment

Other, SOC
Trial Participants

150

Alabama

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, Bilirubin
Treatment

Remdesivir
Trial Participants

52

Alabama

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

40051

Alabama

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, White Blood Cell Count, Monocyte Count, Lymphocyte Count, Neutrophils, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, SOC
Trial Participants

1062

Alabama

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

45

Alabama

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Serious Adverse Events
Treatment

Monoclonal antibody, SOC
Trial Participants

1360

Alabama

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Hospital Discharge, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea
Treatment

Plasma based therapy, SOC
Trial Participants

500

Alabama

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Organ Failure or Dysfunction (SOFA), Renal Outcome (Unspecified)
Treatment

SGLT2, SOC
Trial Participants

900

Alabama

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Serious Adverse Events, Antibodies
Treatment

Plasma based therapy, SOC
Trial Participants

1344

Alabama

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, INR, ALT, AST, Bilirubin
Treatment

Remdesivir, Remdesivir + IFN
Trial Participants

969

Alabama

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Hospitalization
Treatment

Inhaled solution + Other, SOC
Trial Participants

44

Alabama

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

Icatibant + Remdesivir, Other + Remdesivir, PDE4 inhibitor + Remdesivir, Remdesivir, VE-PTP inhibitor + Remdesivir
Trial Participants

1500

Alabama

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, IL-6
Treatment

Other, SOC
Trial Participants

100

Alabama

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Treatment-emergent Adverse Events
Treatment

NA
Trial Participants

100

Alabama

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Treatment-emergent Adverse Events
Treatment

Other, SOC
Trial Participants

436

Alabama

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Anti SARS-COV-2 Titers, Antibodies
Treatment

HCQ, SOC
Trial Participants

58

Alagoas

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Fever
Treatment

HCQ, SOC
Trial Participants

1300

Alagoas

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Organ Failure or Dysfunction (SOFA), Renal Outcome (Unspecified)
Treatment

SGLT2, SOC
Trial Participants

900

Alaska

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6
Treatment

Non-invasive respiratory support, SOC
Trial Participants

70

Alava

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Alava

COVID-19 status

Healthy
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6
Treatment

HCQ, HCQ + NRTIs, NRTIs, SOC
Trial Participants

4000

Albacete

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events
Treatment

TCZ
Trial Participants

500

Albacete

COVID-19 status

Healthy
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6
Treatment

HCQ, HCQ + NRTIs, NRTIs, SOC
Trial Participants

4000

Alberta

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events
Treatment

LPV/r, SOC
Trial Participants

2900

Alberta

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality
Treatment

TCZ
Trial Participants

30

Alberta

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization
Treatment

HCQ, SOC
Trial Participants

70

Alberta

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, Ferritin, IL-6, Tumor Necrosis Factor (Any), White Blood Cell Count, Lymphocyte Count, Platelet Count
Treatment

Vitamins
Trial Participants

64

Alberta

COVID-19 status

Confirmed, Suspected Or Healthy
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, PaO2-FiO2, Blood pH
Treatment

HCQ, SOC
Trial Participants

1309

Alberta

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Organ Failure or Dysfunction (SOFA), Adverse Events, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

ARBs, SOC
Trial Participants

1372

Alberta

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ, SOC
Trial Participants

148

Alberta

COVID-19 status

Suspected
Outcome

Mortality, ICU Admission, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, SpO2
Treatment

Positioning, SOC
Trial Participants

596

Alberta

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Adverse Events, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

Plasma based therapy, SOC
Trial Participants

100

Alberta

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

Plasma based therapy, SOC
Trial Participants

1200

Alborz

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Labor Absenteeism, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Anti SARS-COV-2 Titers
Treatment

SOC, Vaccine
Trial Participants

500

Alborz

COVID-19 status

Confirmed
Outcome

Cough, Fever, Dyspnea, Other Mild Symptoms
Treatment

Alternative therapy
Trial Participants

48

Alessandria

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Adverse Events, C-Reactive Protein, IL-6, Lymphocyte Count, PaO2-FiO2, Radiographic Findings
Treatment

TCZ
Trial Participants

400

Alicante

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, D-Dimer, Troponin
Treatment

Other, SOC
Trial Participants

1034

Alicante

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Adverse Events
Treatment

Nutrition, SOC
Trial Participants

40

Alicante

COVID-19 status

Healthy
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6
Treatment

HCQ, HCQ + NRTIs, NRTIs, SOC
Trial Participants

4000

Amazonas

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, D-Dimer, Troponin
Treatment

Other, SOC
Trial Participants

1034

Amazonas

COVID-19 status

NA
Outcome

Adverse Events, Natural Killer Cell Count
Treatment

NA
Trial Participants

152

Amazonas

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Corticosteroids, SOC
Trial Participants

416

Amman

COVID-19 status

Healthy
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

45000

Amman

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Pneumonia or ARDS, Cough, Fever, Dyspnea, Other Mild Symptoms, Radiographic Findings
Treatment

Stem cells
Trial Participants

5

Amman

COVID-19 status

Healthy
Outcome

IL-1, IL-6, Tumor Necrosis Factor (Any)
Treatment

Vitamins
Trial Participants

100

Amman

COVID-19 status

Healthy
Outcome

IL-1, IL-6, Tumor Necrosis Factor (Any)
Treatment

Nutrition, SOC
Trial Participants

100

Amman

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Viral Load or Clearance, Non-invasive Ventilation, Adverse Events
Treatment

HCQ + AZT, SOC
Trial Participants

200

Amman

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ + AZT, HCQ + Other
Trial Participants

58

Amsterdam

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Viral Load or Clearance, Non-invasive Ventilation
Treatment

ARBs, SOC
Trial Participants

651

Amsterdam

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Hospitalization, Labor Absenteeism, Fever, Other Mild Symptoms, Anti SARS-COV-2 Titers, IgG, IgM or IgA, Antibodies
Treatment

SOC, Vaccine
Trial Participants

1500

Amsterdam

COVID-19 status

Confirmed
Outcome

Adverse Events
Treatment

mAb
Trial Participants

80

Amsterdam

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Amsterdam

COVID-19 status

NA
Outcome

Mortality, ICU Admission
Treatment

Plasma-based therapy
Trial Participants

690

Amsterdam

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, PaO2-FiO2
Treatment

IFN, SOC
Trial Participants

390

Amsterdam

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Labor Absenteeism, Pneumonia or ARDS
Treatment

SOC, Vaccine
Trial Participants

NA

Amsterdam

COVID-19 status

Healthy
Outcome

NA
Treatment

HCQ, SOC
Trial Participants

30000

Amsterdam

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events, White Blood Cell Count, Monocyte Count, Erythrocyte Sedimentation Rate, Creatinine Phosphokinase, CK-MB, eGFR, Myoglobin, Troponin, Procalcitonin, Prothrombin, Fibrinogen, Coagulation Test, ALT, Albumin, Bilirubin, PaO2-FiO2
Treatment

NA
Trial Participants

386

Amsterdam

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Adverse Events, Anti SARS-COV-2 Titers, C-Reactive Protein, IL-2, IL-6, IL-8, LDH, Radiographic Findings
Treatment

TCZ
Trial Participants

NA

Amsterdam

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Labor Absenteeism, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Hyper-Inflammation, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Deep Vein Thrombosis or Pulmonary Embolism, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6, Tumor Necrosis Factor (Any), White Blood Cell Count, D-Dimer, Creatinine Phosphokinase, Bilirubin, Glucose, Antibodies, PaO2-FiO2, Radiographic Findings, Lung Inflamation, Hypoxemia, Quality of Life
Treatment

SOC, TCZ
Trial Participants

450

Amsterdam

COVID-19 status

Confirmed
Outcome

Adverse Events
Treatment

mAB, SOC
Trial Participants

80

Amsterdam

COVID-19 status

Confirmed
Outcome

Hospital Discharge
Treatment

Other, SOC
Trial Participants

120

Amsterdam

COVID-19 status

Confirmed
Outcome

Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, IL-6, Tumor Necrosis Factor (Any), D-Dimer, Antibodies, PaO2-FiO2
Treatment

HCQ, SOC
Trial Participants

8

Amsterdam

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Amsterdam

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO
Treatment

ARBs, SOC
Trial Participants

641

Amsterdam

COVID-19 status

Healthy
Outcome

NA
Treatment

HCQ
Trial Participants

12

Amsterdam

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Fever, Adverse Events, C-Reactive Protein, Respiratory Rate
Treatment

HCQ, HCQ + AZT
Trial Participants

60

Amsterdam

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, Radiographic Findings
Treatment

Plasma based therapy, SOC
Trial Participants

426

Amsterdam

COVID-19 status

Confirmed Or Suspected
Outcome

ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, PaO2-FiO2, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

Anesthetic
Trial Participants

20

Amsterdam

COVID-19 status

NA
Outcome

Clinical Improvement Score (Any), Dyspnea, Adverse Events, Heart Rate, PaO2-FiO2, Quality of Life
Treatment

Device, SOC
Trial Participants

13

Amsterdam

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Adverse Events, IL-6, IL-8, IL-10, Tumor Necrosis Factor (Any), Renal Outcome (Unspecified)
Treatment

Other, SOC
Trial Participants

124

Amsterdam

COVID-19 status

Healthy
Outcome

Monocyte Count
Treatment

SOC, Vaccine, Vaccine + Bisphosphonate, Vaccine + Vaccine
Trial Participants

100

Amsterdam

COVID-19 status

Healthy
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

1600

Amsterdam

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

Plasma based therapy, SOC
Trial Participants

430

Amsterdam

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Clinical Improvement Score (Any), Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events
Treatment

NA
Trial Participants

950

Amsterdam

COVID-19 status

Confirmed
Outcome

NA
Treatment

Positioning, SOC
Trial Participants

342

Amsterdam

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events, Albumin, PaO2-FiO2
Treatment

NA
Trial Participants

386

Amsterdam

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Anti SARS-COV-2 Titers, C-Reactive Protein, Ferritin, IL-6, IL-8, Radiographic Findings
Treatment

TCZ
Trial Participants

354

Amsterdam

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, Quality of Life
Treatment

Other, SOC
Trial Participants

140

Amsterdam

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Amsterdam

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Labor Absenteeism, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Adverse Events
Treatment

Vaccine
Trial Participants

10078

Amsterdam

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, SpO2
Treatment

Other, SOC
Trial Participants

300

Amsterdam

COVID-19 status

Healthy
Outcome

Monocyte Count
Treatment

Vaccine + Bisphosphonate, Vaccine + Vaccine
Trial Participants

NA

Amsterdam

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Secondary CoViD-19 Re-infection, Fever, Other Mild Symptoms
Treatment

SOC, Vaccine
Trial Participants

2014

Amsterdam

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Ancona

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO
Treatment

HCQ, HCQ + JAKi
Trial Participants

116

Andhra Pradesh

COVID-19 status

Confirmed
Outcome

ICU Admission, Invasive Mechanical Ventilation or ECMO
Treatment

Nutrition, SOC
Trial Participants

124

Anhui

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Lung Inflamation
Treatment

SOC, TCM
Trial Participants

100

Anhui

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

60

Anhui

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO
Treatment

FPV, SOC
Trial Participants

210

Anhui

COVID-19 status

Confirmed
Outcome

NA
Treatment

Alternative therapy, SOC
Trial Participants

750

Anhui

COVID-19 status

Confirmed
Outcome

Radiographic Findings
Treatment

SOC, TCM
Trial Participants

200

Anhui

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO
Treatment

SOC, TCZ
Trial Participants

188

Ankara

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, C-Reactive Protein, Ferritin, Lymphocyte Count, SpO2
Treatment

Acalabrutinib, SOC
Trial Participants

177

Ankara

COVID-19 status

Confirmed
Outcome

Mortality, Fever, Adverse Events, Ferritin, Lymphocyte Count, D-Dimer, Heart Rate, PaO2-FiO2, SpO2, Respiratory Rate, Radiographic Findings
Treatment

Ivermectin, SOC
Trial Participants

60

Ankara

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Serious Adverse Events, C-Reactive Protein, Ferritin, Lymphocyte Count, PaO2-FiO2
Treatment

Acalabrutinib, SOC
Trial Participants

163

Ankara

COVID-19 status

Confirmed
Outcome

Radiographic Findings
Treatment

Antivirals + Antimalarial + Antibiotics + Other, SOC
Trial Participants

50

Ankara

COVID-19 status

NA
Outcome

Clinical Improvement Score (Any)
Treatment

Other, SOC
Trial Participants

200

Ankara

COVID-19 status

Confirmed
Outcome

C-Reactive Protein, Ferritin, Lymphocyte Count, D-Dimer, Procalcitonin, Fibrinogen
Treatment

Plasma based therapy, SOC
Trial Participants

60

Ankara

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Serious Adverse Events, IgG, IgM or IgA, Antibodies
Treatment

SOC, Vaccine
Trial Participants

13000

Ankara

COVID-19 status

NA
Outcome

Serious Adverse Events
Treatment

SOC, Vaccine
Trial Participants

43998

Ankara

COVID-19 status

Confirmed
Outcome

Pneumonia or ARDS
Treatment

Other, SOC
Trial Participants

60

Ankara

COVID-19 status

Resolved
Outcome

6-Minute Walking Distance
Treatment

Exercise, Rehabilitation
Trial Participants

122

Ankara

COVID-19 status

Unclear
Outcome

Organ Failure or Dysfunction (SOFA), PaO2-FiO2
Treatment

Other, SOC
Trial Participants

60

Ankara

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO
Treatment

Acalabrutinib, SOC
Trial Participants

140

Ankara

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ + Zinc + Vitamins + AZT
Trial Participants

200

Ankara

COVID-19 status

NA
Outcome

ICU Admission, Invasive Mechanical Ventilation or ECMO
Treatment

JAKi, SOC
Trial Participants

402

Ankara

COVID-19 status

Confirmed
Outcome

NA
Treatment

Monitoring, SOC
Trial Participants

100

Ankara

COVID-19 status

Confirmed Or Suspected
Outcome

Hospital Discharge, Viral Load or Clearance
Treatment

FPV, FPV + AZT, HCQ, HCQ + AZT, HCQ + FPV
Trial Participants

1000

Ankara

COVID-19 status

Confirmed
Outcome

Dyspnea, Other Mild Symptoms
Treatment

Other, SOC
Trial Participants

34

Antalya

COVID-19 status

NA
Outcome

Clinical Improvement Score (Any)
Treatment

Other, SOC
Trial Participants

200

Antananarivo

COVID-19 status

Confirmed
Outcome

NA
Treatment

Other, Other + Vitamins, SOC
Trial Participants

60

Antioquia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Adverse Events, IgG, IgM or IgA, Antibodies
Treatment

Igs, Plasma based therapy, SOC
Trial Participants

75

Antwerp

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Labor Absenteeism, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Organ Failure or Dysfunction (SOFA), Serious Adverse Events, C-Reactive Protein, Ferritin, IL-1, IL-6, Radiographic Findings, Hypoxia
Treatment

Anakinra, Anakinra + Siltuximab, Anakinra + TCZ, Siltuximab, SOC, TCZ
Trial Participants

342

Antwerp

COVID-19 status

NA
Outcome

Adverse Events, IgG, IgM or IgA, Antibodies
Treatment

Vaccine
Trial Participants

260

Aomori

COVID-19 status

NA
Outcome

NA
Treatment

Plasma based therapy
Trial Participants

NA

Arizona

COVID-19 status

Confirmed
Outcome

Mortality, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever
Treatment

Other, SOC
Trial Participants

40

Arizona

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Serious Adverse Events, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Plasma based therapy, SOC
Trial Participants

702

Arizona

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Treatment-emergent Adverse Events, Weight, Height or BMI
Treatment

Remdesivir, SOC
Trial Participants

1230

Arizona

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB, SOC
Trial Participants

2104

Arizona

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Deep Vein Thrombosis or Pulmonary Embolism, Quality of Life, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

Plasma based therapy, SOC
Trial Participants

1000

Arizona

COVID-19 status

NA
Outcome

ICU Admission, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Other Mild Symptoms, Serious Adverse Events, PaO2-FiO2, Respiratory Rate
Treatment

AZT + Antibiotics
Trial Participants

25

Arizona

COVID-19 status

Healthy
Outcome

Mortality, Serious Adverse Events, Interferon (Any), Antibodies
Treatment

SOC, Vaccine
Trial Participants

6578

Arizona

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB
Trial Participants

2970

Arizona

COVID-19 status

Confirmed
Outcome

Hospitalization, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1450

Arizona

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, Adverse Events, SpO2
Treatment

Merimepodib + Remdesivir, Remdesivir
Trial Participants

80

Arizona

COVID-19 status

Confirmed
Outcome

Hospitalization, Clinical Improvement Score (Any)
Treatment

mAb, SOC
Trial Participants

186

Arizona

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

52

Arizona

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Clinical Improvement Score (Any), Fever
Treatment

Other, SOC
Trial Participants

40

Arizona

COVID-19 status

NA
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Organ Failure or Dysfunction (SOFA), Adverse Events
Treatment

Natural Killer Cells, SOC
Trial Participants

86

Arizona

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Arizona

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events, PaO2-FiO2
Treatment

mAb, SOC
Trial Participants

300

Arizona

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Viral Load or Clearance
Treatment

Non-invasive respiratory support, SOC
Trial Participants

500

Arizona

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO, Fever, Other Mild Symptoms, Adverse Events, Respiratory Rate
Treatment

Other, SOC
Trial Participants

190

Arizona

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Visits or Returns to Emergency Department
Treatment

Anticoagulants, SOC
Trial Participants

4000

Arizona

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ, SOC
Trial Participants

479

Arizona

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Fever
Treatment

Hormone therapy, SOC
Trial Participants

198

Arizona

COVID-19 status

Confirmed
Outcome

Mortality, Organ Failure or Dysfunction (SOFA), Serious Adverse Events, Antibodies
Treatment

Remdesivir, Remdesivir + Other
Trial Participants

10000

Arizona

COVID-19 status

Confirmed
Outcome

Blood Gas, Blood Pressure, Heart Rate, SpO2, Respiratory Rate
Treatment

Non-invasive respiratory support
Trial Participants

30

Arizona

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

40051

Arizona

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, Ferritin, Platelet Count, Hemoglobin, D-Dimer, Troponin, Fibrinogen, INR, ALT, AST, Bilirubin, LDH
Treatment

Remdesivir, Remdesivir + mAb
Trial Participants

200

Arizona

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Serious Adverse Events
Treatment

Monoclonal antibody, SOC
Trial Participants

1360

Arizona

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Hospital Discharge, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea
Treatment

Plasma based therapy, SOC
Trial Participants

500

Arizona

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, Ferritin, Platelet Count, Hemoglobin, D-Dimer, Troponin, Fibrinogen, INR, ALT, AST, Bilirubin
Treatment

Remdesivir, Remdesivir + mAb
Trial Participants

200

Arizona

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Serious Adverse Events, Antibodies
Treatment

Plasma based therapy, SOC
Trial Participants

1344

Arizona

COVID-19 status

NA
Outcome

ICU Admission, Hospitalization, Clinical Improvement Score (Any), Fever, Dyspnea, Other Mild Symptoms
Treatment

Plasma based therapy, SOC
Trial Participants

600

Arizona

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Organ Failure or Dysfunction (SOFA), Adverse Events
Treatment

JAKi, SOC
Trial Participants

500

Arizona

COVID-19 status

NA
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance
Treatment

FPV, SOC
Trial Participants

50

Arizona

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, PaO2-FiO2, Blood pH
Treatment

Colchicine, SOC
Trial Participants

6000

Arkansas

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Arkansas

COVID-19 status

NA
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Organ Failure or Dysfunction (SOFA), Adverse Events
Treatment

Natural Killer Cells, SOC
Trial Participants

86

Arkansas

COVID-19 status

Confirmed
Outcome

Hospitalization, Serious Adverse Events
Treatment

Anticoagulants, SOC
Trial Participants

600

Arkansas

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Remdesivir + Costimulation blocker, Remdesivir + mAb, Remdesivir + Other
Trial Participants

2160

Arkansas

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Deep Vein Thrombosis or Pulmonary Embolism, Renal Outcome (Unspecified)
Treatment

Other
Trial Participants

366

Arkansas

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Fever
Treatment

Hormone therapy, SOC
Trial Participants

198

Arkansas

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

40051

Arkansas

COVID-19 status

NA
Outcome

NA
Treatment

Plasma based therapy
Trial Participants

NA

Arkansas

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, PaO2-FiO2, Blood pH
Treatment

Colchicine, SOC
Trial Participants

6000

Astana

COVID-19 status

Confirmed
Outcome

NA
Treatment

Alternative therapy
Trial Participants

200

Astana

COVID-19 status

Healthy
Outcome

Serious Adverse Events, Antibodies
Treatment

SOC, Vaccine
Trial Participants

244

Asturias

COVID-19 status

NA
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Ferritin, Lymphocyte Count, Neutrophils
Treatment

Non-invasive respiratory support, SOC
Trial Participants

208

Asturias

COVID-19 status

NA
Outcome

Mortality, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Adverse Events, Treatment-emergent Adverse Events, C-Reactive Protein, IL-6, MCP-1, Dendritic Cell Count, D-Dimer, Coagulation Test, ALT, Glucose, LDH
Treatment

Plasma based therapy, SOC
Trial Participants

278

Asturias

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Distress
Treatment

Other, SOC
Trial Participants

100

Asturias

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Asturias

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events
Treatment

TCZ
Trial Participants

500

Asturias

COVID-19 status

Healthy
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6
Treatment

HCQ, HCQ + NRTIs, NRTIs, SOC
Trial Participants

4000

Asturias

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Asyut

COVID-19 status

Confirmed Or Healthy
Outcome

Adverse Events, IgG, IgM or IgA
Treatment

Igs
Trial Participants

100

Athens

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance, Pneumonia or ARDS, IL-1, IL-6, IL-8, IL-10, Tumor Necrosis Factor (Any), Monocyte Count
Treatment

Antibiotics
Trial Participants

90

Athens

COVID-19 status

NA
Outcome

Other Mild Symptoms, Organ Failure or Dysfunction (SOFA)
Treatment

Anakinra + Cotrimoxazole
Trial Participants

400

Athens

COVID-19 status

NA
Outcome

Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events, PaO2-FiO2
Treatment

NA
Trial Participants

60

Athens

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), PaO2-FiO2, Radiographic Findings
Treatment

Anakinra, TCZ
Trial Participants

40

Athens

COVID-19 status

NA
Outcome

Dyspnea, Other Mild Symptoms, Quality of Life, Depression, Anxiety
Treatment

Non-invasive respiratory support, SOC
Trial Participants

100

Athens

COVID-19 status

Confirmed
Outcome

NA
Treatment

Plasma based therapy
Trial Participants

60

Athens

COVID-19 status

Healthy
Outcome

IgG, IgM or IgA, Radiographic Findings, Cardiac Outcome (Unspecified)
Treatment

SOC, Vaccine
Trial Participants

900

Athens

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Cough, Dyspnea
Treatment

Antibiotics
Trial Participants

90

Athens

COVID-19 status

Confirmed
Outcome

Hospitalization, Non-invasive Ventilation
Treatment

Remdesivir, SOC
Trial Participants

400

Athens

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, White Blood Cell Count, Monocyte Count, Lymphocyte Count, Neutrophils, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, SOC
Trial Participants

1062

Athens

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, IgG, IgM or IgA, Antibodies, Radiographic Findings, Cardiac Outcome (Unspecified)
Treatment

SOC, Vaccine
Trial Participants

NA

Athens

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any)
Treatment

Hormone therapy, SOC
Trial Participants

60

Athens

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Fever, Deep Vein Thrombosis or Pulmonary Embolism, C-Reactive Protein, White Blood Cell Count, Erythrocyte Sedimentation Rate, D-Dimer, Creatinine Phosphokinase, Fibrinogen, ALT, Bilirubin, Urine Sample, Blood Pressure, PaO2-FiO2, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

Hormone therapy, SOC
Trial Participants

60

Athens

COVID-19 status

Confirmed
Outcome

Mortality, Organ Failure or Dysfunction (SOFA)
Treatment

Anakinra, TCZ
Trial Participants

40

Atlantico

COVID-19 status

NA
Outcome

Mortality, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1300

Atlantico

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ + AZT, SOC
Trial Participants

4000

Aude

COVID-19 status

Confirmed
Outcome

Mortality, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), IL-2, PaO2-FiO2, Patient Positioning
Treatment

Other, SOC
Trial Participants

30

Badajoz

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events
Treatment

TCZ
Trial Participants

500

Baden-Wurttemberg

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Adverse Events, PaO2-FiO2
Treatment

SOC, TCZ
Trial Participants

200

Baden-Wurttemberg

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Adverse Events, IL-6, D-Dimer, Urine Sample
Treatment

ECMO, ECMO + Cytokine removal
Trial Participants

80

Baden-Wurttemberg

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, IL-6
Treatment

ECMO, ECMO + Cytokine removal
Trial Participants

30

Baghdad

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, Serious Adverse Events
Treatment

HCQ + AZT, HCQ + AZT + Other
Trial Participants

16

Baghdad

COVID-19 status

NA
Outcome

NA
Treatment

Plasma based therapy
Trial Participants

NA

Baghdad

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

HCQ + AZT, HCQ + Plasma based therapy + AZT
Trial Participants

49

Baghdad

COVID-19 status

NA
Outcome

Mortality
Treatment

Ivermectin + Antibiotics, SOC
Trial Participants

140

Bahia

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Fever
Treatment

HCQ, SOC
Trial Participants

1300

Bahia

COVID-19 status

Healthy
Outcome

Mortality, Hospitalization, Serious Adverse Events, Antibodies
Treatment

Vaccine
Trial Participants

10300

Bahia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB
Trial Participants

2970

Bahia

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA)
Treatment

Dexamethasone, SOC
Trial Participants

299

Bahia

COVID-19 status

Confirmed
Outcome

Mortality, D-Dimer, Troponin
Treatment

Anticoagulants
Trial Participants

600

Bahia

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Organ Failure or Dysfunction (SOFA), Renal Outcome (Unspecified)
Treatment

SGLT2, SOC
Trial Participants

900

Baleares

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events
Treatment

TCZ
Trial Participants

500

Barcelona

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, C-Reactive Protein, Ferritin, White Blood Cell Count, D-Dimer, LDH, Cardiac Outcome (Unspecified)
Treatment

Corticosteroids, SOC
Trial Participants

300

Barcelona

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, Ferritin, Lymphocyte Count, Platelet Count, Hemoglobin, D-Dimer, ALT, Bilirubin, LDH, SpO2, Hypoxemia
Treatment

Corticosteroids, Siltuximab
Trial Participants

200

Barcelona

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, Respiratory Rate, Hypoxemia
Treatment

Sarilumab, SOC
Trial Participants

420

Barcelona

COVID-19 status

Resolved
Outcome

NA
Treatment

Corticosteroids
Trial Participants

120

Barcelona

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Treatment-emergent Adverse Events, ECG
Treatment

SOC, Trimodulin
Trial Participants

164

Barcelona

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, D-Dimer, Troponin
Treatment

Other, SOC
Trial Participants

1034

Barcelona

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Creatinine Phosphokinase, ALT, AST, Bilirubin, ECG
Treatment

Other
Trial Participants

46

Barcelona

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospital Discharge, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Fever
Treatment

Igs
Trial Participants

100

Barcelona

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, Remdesivir + JAKi
Trial Participants

1034

Barcelona

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Distress
Treatment

Other, SOC
Trial Participants

100

Barcelona

COVID-19 status

Confirmed
Outcome

Hospitalization, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1450

Barcelona

COVID-19 status

Resolved
Outcome

Quality of Life, Depression, Anxiety
Treatment

Rehabilitation, SOC
Trial Participants

102

Barcelona

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Barcelona

COVID-19 status

NA
Outcome

Mortality, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1300

Barcelona

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Clinical Improvement Score (Any), Pneumonia or ARDS, Non-invasive Ventilation, Adverse Events, ECG
Treatment

Antivirals, SOC
Trial Participants

200

Barcelona

COVID-19 status

Confirmed
Outcome

NA
Treatment

Anticoagulants
Trial Participants

164

Barcelona

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO
Treatment

Plasma based therapy, SOC
Trial Participants

116

Barcelona

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, Bilirubin
Treatment

Remdesivir
Trial Participants

52

Barcelona

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Organ Failure or Dysfunction (SOFA), Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, White Blood Cell Count, Lymphocyte Count, Platelet Count, Hemoglobin, Coagulation Test, ALT, AST, Albumin, Bilirubin, Glucose, SpO2, Radiographic Findings, Renal Outcome (Unspecified)
Treatment

SOC, TCZ + mAb
Trial Participants

24

Barcelona

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance, Non-invasive Ventilation, Cough, Fever, Dyspnea, Treatment-emergent Adverse Events, Respiratory Rate
Treatment

Other, SOC
Trial Participants

380

Barcelona

COVID-19 status

Confirmed
Outcome

Hospitalization, Clinical Improvement Score (Any), Pneumonia or ARDS, Non-invasive Ventilation, Treatment-emergent Adverse Events, CD4, PaO2-FiO2, Radiographic Findings
Treatment

HCQ + Antivirals, SOC
Trial Participants

2300

Barcelona

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, Ferritin, LDH
Treatment

Other, SOC
Trial Participants

230

Barcelona

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Barcelona

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events
Treatment

TCZ
Trial Participants

500

Barcelona

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, Quality of Life
Treatment

Other, SOC
Trial Participants

140

Barcelona

COVID-19 status

Confirmed
Outcome

Mortality, Organ Failure or Dysfunction (SOFA), Serious Adverse Events, Antibodies
Treatment

Remdesivir, Remdesivir + Other
Trial Participants

10000

Barcelona

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance
Treatment

Ivermectin, SOC
Trial Participants

102

Barcelona

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, White Blood Cell Count, Monocyte Count, Lymphocyte Count, Neutrophils, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, SOC
Trial Participants

1062

Barcelona

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, SpO2
Treatment

Anakinra, SOC
Trial Participants

180

Barcelona

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Serious Adverse Events
Treatment

Monoclonal antibody, SOC
Trial Participants

1360

Barcelona

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Adverse Events
Treatment

Corticosteroids, SOC
Trial Participants

72

Barcelona

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Labor Absenteeism, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Adverse Events
Treatment

Vaccine
Trial Participants

10078

Barcelona

COVID-19 status

Healthy
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6
Treatment

HCQ, HCQ + NRTIs, NRTIs, SOC
Trial Participants

4000

Barcelona

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA)
Treatment

Cytokine removal, SOC
Trial Participants

40

Barcelona

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Barnet

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Barnsley

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Clinical Improvement Score (Any), Serious Adverse Events
Treatment

Other, SOC
Trial Participants

150

Basel-Stadt

COVID-19 status

Confirmed
Outcome

NA
Treatment

mAb
Trial Participants

NA

Bayern

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Non-invasive Ventilation, Deep Vein Thrombosis or Pulmonary Embolism, Coagulation Test
Treatment

Anticoagulants, SOC
Trial Participants

400

Bayern

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Beijing

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Non-invasive Ventilation, Cough, Other Mild Symptoms, Adverse Events, Radiographic Findings
Treatment

Antivirals, SOC
Trial Participants

342

Beijing

COVID-19 status

Confirmed
Outcome

C-Reactive Protein, IL-6, PaO2-FiO2, Radiographic Findings
Treatment

Non-invasive respiratory support, SOC
Trial Participants

45

Beijing

COVID-19 status

Confirmed
Outcome

NA
Treatment

FPV, SOC
Trial Participants

256

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, Viral Load or Clearance, Pneumonia or ARDS, Cough, Fever, Dyspnea, Treatment-emergent Adverse Events, C-Reactive Protein, Creatinine Phosphokinase, ALT, CD4, CD8
Treatment

SOC, Stem cells
Trial Participants

20

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Fever, Organ Failure or Dysfunction (SOFA), Deep Vein Thrombosis or Pulmonary Embolism
Treatment

SOC, TCM
Trial Participants

100

Beijing

COVID-19 status

Confirmed
Outcome

ICU Admission, PaO2-FiO2, Respiratory Rate
Treatment

SOC, TCM
Trial Participants

42

Beijing

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Fever, White Blood Cell Count, Monocyte Count, Hemoglobin, Erythrocyte Sedimentation Rate, Radiographic Findings
Treatment

LPV/r, LPV/r + TCM, TCM
Trial Participants

60

Beijing

COVID-19 status

NA
Outcome

Viral Load or Clearance, Fever, Other Mild Symptoms
Treatment

SOC, TCM
Trial Participants

2000

Beijing

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Pneumonia or ARDS, Fever, Adverse Events, Serious Adverse Events, PaO2-FiO2, Respiratory Rate
Treatment

SOC, TCM
Trial Participants

120

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Radiographic Findings
Treatment

Corticosteroids, SOC
Trial Participants

80

Beijing

COVID-19 status

NA
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6
Treatment

NA
Trial Participants

10

Beijing

COVID-19 status

Confirmed
Outcome

ICU Admission, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Other Mild Symptoms, Adverse Events, PaO2-FiO2, Respiratory Rate
Treatment

LPV/r, Other
Trial Participants

160

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

FPV, FPV + TCZ, TCZ
Trial Participants

150

Beijing

COVID-19 status

Healthy
Outcome

Antibodies
Treatment

SOC, Vaccine
Trial Participants

422

Beijing

COVID-19 status

Confirmed
Outcome

Fever, C-Reactive Protein, Ferritin, Radiographic Findings, Quality of Life
Treatment

SOC, TCM
Trial Participants

300

Beijing

COVID-19 status

Healthy
Outcome

Adverse Events
Treatment

mAb, SOC
Trial Participants

40

Beijing

COVID-19 status

NA
Outcome

PaO2-FiO2
Treatment

Non-invasive respiratory support
Trial Participants

200

Beijing

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), C-Reactive Protein, Ferritin, IL-6, Interferon (Any), Lymphocyte Count, D-Dimer, Creatinine Phosphokinase, CK-MB, eGFR, Myoglobin, Troponin, Procalcitonin, Prothrombin, Coagulation Test, ALT, Albumin, Bilirubin, IgG, IgM or IgA, Blood Gas, ECG, SpO2, 6-Minute Walking Distance, Radiographic Findings, Quality of Life, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

SOC, Stem cells
Trial Participants

200

Beijing

COVID-19 status

Healthy
Outcome

Mortality, Pneumonia or ARDS, Serious Adverse Events, Antibodies
Treatment

SOC, Vaccine
Trial Participants

15000

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Pneumonia or ARDS, Non-invasive Ventilation, Adverse Events, C-Reactive Protein, Ferritin, IL-6, White Blood Cell Count, Neutrophils, Erythrocyte Sedimentation Rate, D-Dimer, Creatinine Phosphokinase, CK-MB, LDH, Antibodies, Radiographic Findings
Treatment

SOC, TCM
Trial Participants

50

Beijing

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Fever, Serious or Seconday Infections, C-Reactive Protein, Radiographic Findings
Treatment

FPV, HCQ + FPV, SOC
Trial Participants

150

Beijing

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Fever, Serious or Seconday Infections, C-Reactive Protein, Radiographic Findings
Treatment

HCQ, SOC
Trial Participants

300

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events
Treatment

Igs, SOC
Trial Participants

80

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), C-Reactive Protein, IL-6, Procalcitonin, Radiographic Findings
Treatment

mAb, Other
Trial Participants

120

Beijing

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Pneumonia or ARDS, Fever, C-Reactive Protein, D-Dimer, PaO2-FiO2, Respiratory Rate, Radiographic Findings
Treatment

mAb
Trial Participants

20

Beijing

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Adverse Events
Treatment

LPV/r + IFN, SOC
Trial Participants

90

Beijing

COVID-19 status

Resolved
Outcome

Pneumonia or ARDS, Dyspnea, 6-Minute Walking Distance, Radiographic Findings
Treatment

SOC, TCM
Trial Participants

160

Beijing

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Cough, Fever, Dyspnea, Other Mild Symptoms, C-Reactive Protein, Erythrocyte Sedimentation Rate, CK-MB, ALT, PaO2-FiO2, Radiographic Findings
Treatment

Umifenovir, Umifenovir + IFN
Trial Participants

100

Beijing

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Cough, Fever, Dyspnea, Other Mild Symptoms, C-Reactive Protein, Erythrocyte Sedimentation Rate, CK-MB, ALT, PaO2-FiO2, Radiographic Findings
Treatment

LPV/r, Oseltamivir, SOC, Umifenovir
Trial Participants

400

Beijing

COVID-19 status

Resolved
Outcome

Viral Load or Clearance, Pneumonia or ARDS, Cough, Dyspnea
Treatment

FPV, FPV + HCQ, SOC
Trial Participants

150

Beijing

COVID-19 status

Confirmed
Outcome

ICU Admission, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Other Mild Symptoms, Adverse Events, C-Reactive Protein, Erythrocyte Sedimentation Rate, Creatinine Phosphokinase, CK-MB, ALT, PaO2-FiO2, Respiratory Rate
Treatment

Oseltamivir, Oseltamivir + Antivirals, Other + Oseltamivir
Trial Participants

60

Beijing

COVID-19 status

Confirmed
Outcome

ICU Admission, Clinical Improvement Score (Any), Viral Load or Clearance, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Organ Failure or Dysfunction (SOFA), PaO2-FiO2, Radiographic Findings
Treatment

Corticosteroids
Trial Participants

100

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Antibodies, PaO2-FiO2, Radiographic Findings
Treatment

Igs
Trial Participants

10

Beijing

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any)
Treatment

mAb, SOC
Trial Participants

140

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, Viral Load or Clearance, Fever, Adverse Events, Serious Adverse Events, C-Reactive Protein, IL-1, IL-2, IL-6, IL-8, CK-MB, Procalcitonin
Treatment

NA
Trial Participants

9

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, PaO2-FiO2, Respiratory Rate
Treatment

SOC, TCM
Trial Participants

550

Beijing

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Fever, 3CL Mpro, White Blood Cell Count, Monocyte Count, Natural Killer Cell Count, Dendritic Cell Count, Neutrophils, Creatinine Phosphokinase, CK-MB, ALT, Urine Sample, Stool Sample, Radiographic Findings
Treatment

LPV/r + IFN, LPV/r + IFN + TCM
Trial Participants

20

Beijing

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospitalization, Visits or Returns to Emergency Department, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Other Mild Symptoms, Adverse Events, Serious Adverse Events
Treatment

DAA + IFN
Trial Participants

11

Beijing

COVID-19 status

Healthy
Outcome

Adverse Events, Antibodies
Treatment

mAb, SOC
Trial Participants

33

Beijing

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Fever, Treatment-emergent Adverse Events, C-Reactive Protein, Respiratory Rate, Radiographic Findings
Treatment

NA
Trial Participants

20

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Fever, C-Reactive Protein, Radiographic Findings
Treatment

FPV, FPV + TCZ, TCZ
Trial Participants

150

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Viral Load or Clearance, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Other Mild Symptoms, Serious Adverse Events, PaO2-FiO2, Respiratory Rate
Treatment

Remdesivir, SOC
Trial Participants

308

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Treatment-emergent Adverse Events, Serious Adverse Events, PaO2-FiO2, Respiratory Rate
Treatment

Remdesivir, SOC
Trial Participants

237

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Clinical Improvement Score (Any), PaO2-FiO2, Respiratory Rate, Hypoxia, Hypoxemia
Treatment

SOC, Vitamins
Trial Participants

56

Beijing

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance
Treatment

Ivermectin, SOC
Trial Participants

60

Beijing

COVID-19 status

Healthy
Outcome

Adverse Events
Treatment

Other
Trial Participants

25

Beijing

COVID-19 status

Confirmed
Outcome

PaO2-FiO2, Radiographic Findings, Hypoxia, Hypoxemia
Treatment

Stem cells
Trial Participants

24

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Dyspnea, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events
Treatment

Plasma based therapy, SOC
Trial Participants

50

Beijing

COVID-19 status

Confirmed
Outcome

IgG, IgM or IgA, Antibodies
Treatment

SOC, Vaccine
Trial Participants

471

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events
Treatment

Plasma based therapy, SOC
Trial Participants

200

Beijing

COVID-19 status

Confirmed
Outcome

Stool Sample
Treatment

Alternative therapy
Trial Participants

76

Beijing

COVID-19 status

NA
Outcome

PaO2-FiO2
Treatment

Non-invasive respiratory support
Trial Participants

20

Beijing

COVID-19 status

Confirmed
Outcome

Cough, Fever, Dyspnea
Treatment

LPV/r, LPV/r + TCM
Trial Participants

80

Beijing

COVID-19 status

Confirmed
Outcome

NA
Treatment

Corticosteroids, SOC
Trial Participants

86

Beijing

COVID-19 status

Healthy
Outcome

Adverse Events, Radiographic Findings
Treatment

mAb, SOC
Trial Participants

12

Beijing

COVID-19 status

Healthy
Outcome

Adverse Events, Radiographic Findings
Treatment

mAb, SOC
Trial Participants

12

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Fever, Adverse Events, Serious Adverse Events, IL-6, IL-10, Tumor Necrosis Factor (Any)
Treatment

Other
Trial Participants

19

Beijing

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Other Mild Symptoms, IL-6, Tumor Necrosis Factor (Any), White Blood Cell Count, Natural Killer Cell Count, Radiographic Findings
Treatment

SOC, Stem cells
Trial Participants

20

Beijing

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Non-invasive Ventilation, Cough, Fever, Other Mild Symptoms, Adverse Events, Radiographic Findings
Treatment

DAA, SOC
Trial Participants

342

Beijing

COVID-19 status

Confirmed
Outcome

Pneumonia or ARDS
Treatment

Immunomodulators, SOC
Trial Participants

30

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events, IL-6, IL-10, Tumor Necrosis Factor (Any)
Treatment

Cytokine removal
Trial Participants

19

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events, IgG, IgM or IgA
Treatment

HCQ
Trial Participants

100

Beijing

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Beijing

COVID-19 status

Healthy
Outcome

Pneumonia or ARDS, Cough, Fever, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, Radiographic Findings
Treatment

IFN, SOC
Trial Participants

450

Beijing

COVID-19 status

NA
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

744

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, IgG, IgM or IgA
Treatment

HCQ
Trial Participants

100

Beijing

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Fever, Radiographic Findings
Treatment

Carrimycin, HCQ or LPV/r or Umifenovir
Trial Participants

520

Beijing

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance
Treatment

SOC, TCM
Trial Participants

204

Beijing

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Cough, Fever, Dyspnea
Treatment

SOC, TCM
Trial Participants

120

Beijing

COVID-19 status

Confirmed
Outcome

NA
Treatment

Psychological therapy
Trial Participants

1600

Beijing

COVID-19 status

Confirmed
Outcome

NA
Treatment

TCM
Trial Participants

300

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Treatment-emergent Adverse Events, PaO2-FiO2
Treatment

TCM
Trial Participants

116

Beijing

COVID-19 status

Confirmed
Outcome

Hospitalization, Visits or Returns to Emergency Department
Treatment

Antimalarial, SOC
Trial Participants

275

Beijing

COVID-19 status

Confirmed Or Suspected
Outcome

Clinical Improvement Score (Any)
Treatment

SOC, Stem cells
Trial Participants

60

Beijing

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Fever, Serious or Seconday Infections, Lymphocyte Count, IgG, IgM or IgA, Blood Pressure, Heart Rate, Respiratory Rate, Radiographic Findings
Treatment

HCQ, SOC
Trial Participants

78

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Dyspnea, Radiographic Findings
Treatment

LPV/r + IFN + TCM + Non-invasive respiratory support, LPV/r + Non-invasive respiratory support + IFN
Trial Participants

150

Beijing

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Radiographic Findings
Treatment

SOC, Stem cells
Trial Participants

40

Beijing

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Fever
Treatment

LPV/r + IFN, TCM
Trial Participants

348

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, IL-1, IL-2, IL-6, IL-7, IL-8, IL-10, Tumor Necrosis Factor (Any), Granulocyte Stimulaiting Factor, IP-10, MCP-1, MIP-1
Treatment

Immunomodulators, SOC
Trial Participants

40

Beijing

COVID-19 status

Confirmed Or Suspected
Outcome

ICU Admission, Clinical Improvement Score (Any), Viral Load or Clearance, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA)
Treatment

SOC, TCM
Trial Participants

300

Beijing

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Other Mild Symptoms
Treatment

FPV
Trial Participants

60

Beijing

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any)
Treatment

TCM
Trial Participants

60

Beijing

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Beijing

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Cough, Fever, Dyspnea, Respiratory Rate, Radiographic Findings
Treatment

IFN, SOC
Trial Participants

300

Beijing

COVID-19 status

Confirmed
Outcome

NA
Treatment

SOC, Stem cells
Trial Participants

120

Beijing

COVID-19 status

NA
Outcome

ICU Admission, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Serious Adverse Events
Treatment

NA
Trial Participants

10

Beijing

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Radiographic Findings, Quality of Life
Treatment

SOC, TCM
Trial Participants

60

Beijing

COVID-19 status

Healthy
Outcome

IgG, IgM or IgA, Antibodies
Treatment

SOC, Vaccine
Trial Participants

942

Beijing

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Fever
Treatment

Carrimycin, LPV/r
Trial Participants

520

Beijing

COVID-19 status

Confirmed
Outcome

Fever, Radiographic Findings, Quality of Life
Treatment

SOC, TCM
Trial Participants

408

Beijing

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Fever
Treatment

SOC, TCM
Trial Participants

60

Beirut

COVID-19 status

Confirmed
Outcome

NA
Treatment

HCQ, LPV/r, LPV/r + IFN, Remdesivir, SOC
Trial Participants

10000

Belfast

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Serious Adverse Events
Treatment

Monoclonal antibody, SOC
Trial Participants

1360

Bergamo

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Non-invasive Ventilation
Treatment

Plasma based therapy
Trial Participants

10

Bergamo

COVID-19 status

Confirmed Or Suspected
Outcome

IL-1, IL-2, IL-6, IL-7, IL-10, Tumor Necrosis Factor (Any), MCP-1, IgG, IgM or IgA, Antibodies, Radiographic Findings
Treatment

Igs
Trial Participants

10

Bergamo

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Bergamo

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Berlin

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, Respiratory Rate, Hypoxemia
Treatment

Sarilumab, SOC
Trial Participants

420

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Serious Adverse Events, C-Reactive Protein, Ferritin, Lymphocyte Count, PaO2-FiO2
Treatment

Acalabrutinib, SOC
Trial Participants

163

Berlin

COVID-19 status

Confirmed
Outcome

NA
Treatment

FPV, SOC
Trial Participants

256

Berlin

COVID-19 status

Confirmed
Outcome

Adverse Events, PaO2-FiO2
Treatment

SOC, Stem cells
Trial Participants

64

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ, SOC
Trial Participants

220

Berlin

COVID-19 status

Confirmed
Outcome

ICU Admission, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Adverse Events, IL-6, D-Dimer, Urine Sample
Treatment

ECMO, ECMO + Cytokine removal
Trial Participants

80

Berlin

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, Anti SARS-COV-2 Titers, C-Reactive Protein, Ferritin, IL-6, Radiographic Findings
Treatment

JAKi
Trial Participants

15

Berlin

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, PaO2-FiO2
Treatment

IFN, SOC
Trial Participants

390

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Renal Outcome (Unspecified)
Treatment

IFN, LPV/r, Remdesivir, SOC
Trial Participants

NA

Berlin

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, D-Dimer, Troponin
Treatment

Other, SOC
Trial Participants

1034

Berlin

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), SpO2
Treatment

mAb, SOC
Trial Participants

270

Berlin

COVID-19 status

NA
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6
Treatment

NA
Trial Participants

17

Berlin

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

ECMO
Trial Participants

200

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, IL-6, Renal Outcome (Unspecified)
Treatment

Cytokine removal, SOC
Trial Participants

100

Berlin

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA)
Treatment

Non-invasive respiratory support, SOC
Trial Participants

200

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, SpO2, Respiratory Rate
Treatment

DAA, HCQ, SOC
Trial Participants

90

Berlin

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance
Treatment

Hygiene
Trial Participants

50

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Non-invasive Ventilation, Deep Vein Thrombosis or Pulmonary Embolism, Coagulation Test
Treatment

Anticoagulants, SOC
Trial Participants

400

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events, White Blood Cell Count, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose, Renal Outcome (Unspecified)
Treatment

Remdesivir, SOC
Trial Participants

440

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization
Treatment

HCQ, SOC
Trial Participants

350

Berlin

COVID-19 status

Confirmed
Outcome

Hospitalization, Visits or Returns to Emergency Department
Treatment

Device + Other, SOC
Trial Participants

600

Berlin

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospitalization, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Adverse Events, Antibodies
Treatment

Plasma based therapy, SOC
Trial Participants

120

Berlin

COVID-19 status

Healthy
Outcome

Fever, Other Mild Symptoms, Treatment-emergent Adverse Events, Antibodies
Treatment

Vaccine
Trial Participants

120

Berlin

COVID-19 status

NA
Outcome

Serious Adverse Events
Treatment

SOC, Vaccine
Trial Participants

43998

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Labor Absenteeism, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Hyper-Inflammation, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Deep Vein Thrombosis or Pulmonary Embolism, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6, Tumor Necrosis Factor (Any), White Blood Cell Count, D-Dimer, Creatinine Phosphokinase, Bilirubin, Glucose, Antibodies, PaO2-FiO2, Radiographic Findings, Lung Inflamation, Hypoxemia, Quality of Life
Treatment

SOC, TCZ
Trial Participants

450

Berlin

COVID-19 status

NA
Outcome

NA
Treatment

Plasma based therapy
Trial Participants

NA

Berlin

COVID-19 status

Confirmed
Outcome

Treatment-emergent Adverse Events
Treatment

Remdesivir
Trial Participants

2500

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Labor Absenteeism, Fever, SpO2, Respiratory Rate
Treatment

Other, SOC
Trial Participants

230

Berlin

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Antibodies
Treatment

JAKi
Trial Participants

200

Berlin

COVID-19 status

Unclear
Outcome

Adverse Events
Treatment

Device
Trial Participants

20

Berlin

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), C-Reactive Protein, Troponin
Treatment

NA
Trial Participants

334

Berlin

COVID-19 status

Healthy
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

59

Berlin

COVID-19 status

Confirmed
Outcome

Fever, Other Mild Symptoms, Treatment-emergent Adverse Events, Antibodies
Treatment

Vaccine
Trial Participants

NA

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Hyper-Inflammation, Radiographic Findings
Treatment

JAKi
Trial Participants

NA

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

300

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO
Treatment

Plasma based therapy, SOC
Trial Participants

NA

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance
Treatment

HCQ, SOC
Trial Participants

NA

Berlin

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, Ferritin, IL-6, D-Dimer, Procalcitonin, Shock, Quality of Life, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

SOC, TCZ
Trial Participants

NA

Berlin

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO
Treatment

Acalabrutinib, SOC
Trial Participants

140

Berlin

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, Anti SARS-COV-2 Titers, C-Reactive Protein, IL-6, Tumor Necrosis Factor (Any)
Treatment

Plasma based therapy, SOC
Trial Participants

106

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization
Treatment

HCQ, SOC
Trial Participants

NA

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, LDH
Treatment

Antihypertensive, SOC
Trial Participants

200

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Adverse Events, C-Reactive Protein, Tumor Necrosis Factor (Any), Interferon (Any), D-Dimer, Weight, Height or BMI, Troponin, Procalcitonin, LDH, IgG, IgM or IgA, Antibodies, Blood Pressure, Heart Rate, ECG, SpO2, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

Immunomodulators, SOC
Trial Participants

230

Berlin

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

Anticoagulants
Trial Participants

172

Berlin

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ, LPV/r, Remdesivir, SOC
Trial Participants

7000

Berlin

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, Quality of Life
Treatment

Other, SOC
Trial Participants

140

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, SpO2
Treatment

JAKi, SOC
Trial Participants

402

Berlin

COVID-19 status

Confirmed
Outcome

Lymphocyte Count, D-Dimer, Antibodies
Treatment

SOC, Stem cells
Trial Participants

40

Berlin

COVID-19 status

NA
Outcome

ICU Admission, Invasive Mechanical Ventilation or ECMO
Treatment

JAKi, SOC
Trial Participants

402

Berlin

COVID-19 status

Confirmed
Outcome

NA
Treatment

HCQ, LPV/r, LPV/r + IFN, Remdesivir, SOC
Trial Participants

10000

Berlin

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Fever
Treatment

SOC, Vaccine
Trial Participants

NA

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, White Blood Cell Count, Monocyte Count, Lymphocyte Count, Neutrophils, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, SOC
Trial Participants

1062

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events, Monocyte Count, Neutrophils, Platelet Count, Hemoglobin, ALT, AST, Bilirubin, Glucose, ECG
Treatment

Other, SOC
Trial Participants

183

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious or Seconday Infections, Serious Adverse Events, ALT
Treatment

Sarilumab, SOC
Trial Participants

460

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Berlin

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Fever, Adverse Events, C-Reactive Protein, Ferritin, IL-6, Weight, Height or BMI, Coagulation Test, LDH, Blood Pressure, SpO2, Respiratory Rate
Treatment

Other, SOC
Trial Participants

NA

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, SpO2
Treatment

Other, SOC
Trial Participants

300

Berlin

COVID-19 status

Confirmed
Outcome

ICU Admission, C-Reactive Protein, Ferritin, IL-6, IgG, IgM or IgA
Treatment

JAKi
Trial Participants

NA

Berlin

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Fever
Treatment

SOC, Vaccine
Trial Participants

NA

Berlin

COVID-19 status

NA
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO
Treatment

NA
Trial Participants

220

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO
Treatment

ARBs, SOC
Trial Participants

NA

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

300

Berlin

COVID-19 status

Healthy
Outcome

Serious Adverse Events, Antibodies
Treatment

SOC, Vaccine
Trial Participants

284

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, C-Reactive Protein, Ferritin, Lymphocyte Count, SpO2
Treatment

Acalabrutinib, SOC
Trial Participants

177

Berlin

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, SpO2
Treatment

Other, SOC
Trial Participants

1034

Bern

COVID-19 status

Confirmed
Outcome

Mortality, C-Reactive Protein, Ferritin, White Blood Cell Count, PaO2-FiO2
Treatment

Radiation therapy
Trial Participants

22

Bern

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), C-Reactive Protein, Hemoglobin, D-Dimer, eGFR, Glucose, Renal Outcome (Unspecified)
Treatment

mAb, SOC
Trial Participants

116

Bern

COVID-19 status

Confirmed
Outcome

NA
Treatment

Nutrition
Trial Participants

284

Bern

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Labor Absenteeism
Treatment

SOC, TCZ
Trial Participants

5

Bern

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Deep Vein Thrombosis or Pulmonary Embolism, Coagulation Test
Treatment

Anticoagulants
Trial Participants

200

Bern

COVID-19 status

Confirmed
Outcome

NA
Treatment

Other, SOC
Trial Participants

90

Bern

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Non-invasive Ventilation, PaO2-FiO2
Treatment

Other, SOC
Trial Participants

120

Bern

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Coagulation Test
Treatment

Anticoagulants, SOC
Trial Participants

1000

Bern

COVID-19 status

Confirmed
Outcome

Treatment-emergent Adverse Events
Treatment

Remdesivir
Trial Participants

2500

Bern

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), C-Reactive Protein, IL-6, MCP-1, Procalcitonin, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

Anesthetic, SOC
Trial Participants

64

Bern

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Serious Adverse Events
Treatment

Plasma based therapy
Trial Participants

15

Bern

COVID-19 status

NA
Outcome

NA
Treatment

HCQ, LPV/r
Trial Participants

300

Bern

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ, LPV/r, Remdesivir, SOC
Trial Participants

7000

Bern

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Bern

COVID-19 status

Confirmed
Outcome

NA
Treatment

HCQ, SOC
Trial Participants

800

Bern

COVID-19 status

Confirmed
Outcome

NA
Treatment

HCQ, LPV/r, LPV/r + IFN, Remdesivir, SOC
Trial Participants

10000

Bern

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), C-Reactive Protein, Lymphocyte Count, Procalcitonin
Treatment

Inhaled solution
Trial Participants

80

Bern

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization
Treatment

Vitamins
Trial Participants

80

Bern

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Bio-Bio

COVID-19 status

Healthy
Outcome

NA
Treatment

Alternative therapy, SOC
Trial Participants

524

Birmingham

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Pneumonia or ARDS
Treatment

AZT, SOC
Trial Participants

800

Birmingham

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, Bilirubin
Treatment

Remdesivir
Trial Participants

52

Bissau

COVID-19 status

Healthy
Outcome

Mortality
Treatment

SOC, Vaccine
Trial Participants

3400

Bissau

COVID-19 status

Unclear
Outcome

Mortality
Treatment

Device, SOC
Trial Participants

66000

Bizkaia

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Bizkaia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events
Treatment

TCZ
Trial Participants

500

Bizkaia

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Labor Absenteeism, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Adverse Events
Treatment

Vaccine
Trial Participants

10078

Bizkaia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Bogota

COVID-19 status

Healthy
Outcome

Serious Adverse Events
Treatment

NRTIs, SOC
Trial Participants

950

Bogota

COVID-19 status

Confirmed
Outcome

Adverse Events
Treatment

Ivermectin, SOC
Trial Participants

400

Bogota

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), IL-6, Hemoglobin, D-Dimer, Procalcitonin, AST, Bilirubin, Antibodies, Radiographic Findings
Treatment

Plasma based therapy, SOC
Trial Participants

60

Bogota

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

HCQ + LPV/r or AZT, Stem cells
Trial Participants

40

Bogota

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ + AZT, SOC
Trial Participants

4000

Bogota

COVID-19 status

NA
Outcome

ICU Admission, Hospitalization, Hospital Discharge, Viral Load or Clearance, Household Members with CoViD-19, Labor Absenteeism, Adverse Events, Treatment-emergent Adverse Events
Treatment

NA
Trial Participants

10

Bogota

COVID-19 status

NA
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Adverse Events
Treatment

HCQ, SOC
Trial Participants

86

Bogota

COVID-19 status

Healthy
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

60000

Bogota

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO
Treatment

mAb, SOC
Trial Participants

800

Bogota

COVID-19 status

NA
Outcome

Mortality, Viral Load or Clearance, Adverse Events, Serious Adverse Events
Treatment

SOC, Vaccine
Trial Participants

1000

Bogota

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO, Hypoxemia
Treatment

Other, SOC
Trial Participants

284

Bogota

COVID-19 status

NA
Outcome

ICU Admission, Invasive Mechanical Ventilation or ECMO
Treatment

JAKi, SOC
Trial Participants

402

Bogota

COVID-19 status

Confirmed Or Suspected
Outcome

ICU Admission, Hospitalization, Clinical Improvement Score (Any), Treatment-emergent Adverse Events
Treatment

HCQ + LPV/r, HCQ + LPV/r + Alternative therapy
Trial Participants

100

Bogota

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

Plasma based therapy, SOC
Trial Participants

231

Bogota

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

40051

Bogota

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, Serious Adverse Events
Treatment

AZT, HCQ, LPV/r, SOC
Trial Participants

1200

Bolivar

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ + AZT, SOC
Trial Participants

4000

Bologna

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Serious Adverse Events, C-Reactive Protein, Ferritin, Lymphocyte Count, PaO2-FiO2
Treatment

Acalabrutinib, SOC
Trial Participants

163

Bologna

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance
Treatment

Ivermectin, SOC
Trial Participants

102

Bologna

COVID-19 status

Confirmed
Outcome

Hospitalization
Treatment

Anticoagulants
Trial Participants

300

Bradford

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Bradford

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Clinical Improvement Score (Any), Serious Adverse Events
Treatment

Other, SOC
Trial Participants

150

Brandenburg

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Non-invasive Ventilation, Deep Vein Thrombosis or Pulmonary Embolism, Coagulation Test
Treatment

Anticoagulants, SOC
Trial Participants

400

Brasilia

COVID-19 status

Confirmed
Outcome

NA
Treatment

Stem cells
Trial Participants

90

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Serious Adverse Events, C-Reactive Protein, Ferritin, Lymphocyte Count, PaO2-FiO2
Treatment

Acalabrutinib, SOC
Trial Participants

163

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Antivirals, SOC
Trial Participants

50

Brasilia

COVID-19 status

Confirmed
Outcome

Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, IL-6, Radiographic Findings, Renal Outcome (Unspecified)
Treatment

Other, SOC
Trial Participants

100

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Platelet Count, Prothrombin, Fibrinogen
Treatment

Anticoagulants, SOC
Trial Participants

462

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

Other, SOC
Trial Participants

310

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO
Treatment

SOC, TCZ
Trial Participants

60

Brasilia

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Viral Load or Clearance, Non-invasive Ventilation, Fever, Treatment-emergent Adverse Events, Serious Adverse Events, IL-6, PaO2-FiO2
Treatment

NA
Trial Participants

120

Brasilia

COVID-19 status

Confirmed
Outcome

Hospital Discharge
Treatment

Device, SOC
Trial Participants

30

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Viral Load or Clearance, Adverse Events, Radiographic Findings, Depression, Anxiety
Treatment

Alternative therapy, SOC
Trial Participants

100

Brasilia

COVID-19 status

Confirmed
Outcome

NA
Treatment

Antivirals, SOC
Trial Participants

300

Brasilia

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Fever
Treatment

HCQ, SOC
Trial Participants

1300

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, IL-6, Tumor Necrosis Factor (Any), D-Dimer, Angiotensins, ACE, ECG, SpO2
Treatment

Other, SOC
Trial Participants

465

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any)
Treatment

mAb, SOC
Trial Participants

573

Brasilia

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Treatment-emergent Adverse Events, D-Dimer, Antibodies, PaO2-FiO2
Treatment

HCQ, SOC
Trial Participants

630

Brasilia

COVID-19 status

Healthy
Outcome

Mortality, Hospitalization, Serious Adverse Events, Antibodies
Treatment

Vaccine
Trial Participants

10300

Brasilia

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation
Treatment

Plasma based therapy, SOC
Trial Participants

219

Brasilia

COVID-19 status

NA
Outcome

Serious Adverse Events
Treatment

SOC, Vaccine
Trial Participants

43998

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Brasilia

COVID-19 status

NA
Outcome

Invasive Mechanical Ventilation or ECMO
Treatment

SOC, TCZ
Trial Participants

379

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB
Trial Participants

2970

Brasilia

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA)
Treatment

Dexamethasone, SOC
Trial Participants

299

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

52

Brasilia

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Clinical Improvement Score (Any), C-Reactive Protein
Treatment

Acalabrutinib
Trial Participants

48

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ + AZT, SOC
Trial Participants

4000

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Brasilia

COVID-19 status

NA
Outcome

Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA)
Treatment

Antisense therapy, SOC
Trial Participants

110

Brasilia

COVID-19 status

Healthy
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

60000

Brasilia

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO
Treatment

Acalabrutinib, SOC
Trial Participants

140

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

JAKi, SOC
Trial Participants

260

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea
Treatment

HCQ + AZT
Trial Participants

400

Brasilia

COVID-19 status

Unclear
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any)
Treatment

HCQ + AZT
Trial Participants

200

Brasilia

COVID-19 status

NA
Outcome

NA
Treatment

ARBs + ACEi, SOC
Trial Participants

700

Brasilia

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Quality of Life
Treatment

HCQ, HCQ + AZT
Trial Participants

440

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, ECG, SpO2
Treatment

Other, SOC
Trial Participants

150

Brasilia

COVID-19 status

Confirmed
Outcome

NA
Treatment

mAb, Other, SOC
Trial Participants

390

Brasilia

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO, Fever, Other Mild Symptoms, Adverse Events, Respiratory Rate
Treatment

Other, SOC
Trial Participants

190

Brasilia

COVID-19 status

Confirmed
Outcome

Treatment-emergent Adverse Events, Serious Adverse Events
Treatment

Other, SOC
Trial Participants

66

Brasilia

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance
Treatment

Ivermectin, SOC
Trial Participants

64

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, D-Dimer, Troponin
Treatment

Anticoagulants
Trial Participants

600

Brasilia

COVID-19 status

Confirmed Or Suspected
Outcome

NA
Treatment

Anticoagulants, SOC
Trial Participants

90

Brasilia

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance, Non-invasive Ventilation, Cough, Fever, Dyspnea, Treatment-emergent Adverse Events, Respiratory Rate
Treatment

Other, SOC
Trial Participants

380

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ, LPV/r, Remdesivir, SOC
Trial Participants

7000

Brasilia

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, Quality of Life
Treatment

Other, SOC
Trial Participants

140

Brasilia

COVID-19 status

Healthy
Outcome

Invasive Mechanical Ventilation or ECMO, Adverse Events, Heart Rate, ECG
Treatment

HCQ, SOC
Trial Participants

400

Brasilia

COVID-19 status

Confirmed
Outcome

Hospitalization
Treatment

Hormone therapy + Ivermectin + AZT, Ivermectin + AZT
Trial Participants

381

Brasilia

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Non-invasive Ventilation, Fever, SpO2, Respiratory Rate
Treatment

Remdesivir, Remdesivir + TCZ
Trial Participants

500

Brasilia

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO
Treatment

Antivirals, SOC
Trial Participants

584

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission
Treatment

Antihypertensive
Trial Participants

240

Brasilia

COVID-19 status

Healthy
Outcome

Adverse Events
Treatment

SOC, Vaccine
Trial Participants

13060

Brasilia

COVID-19 status

NA
Outcome

ICU Admission, Invasive Mechanical Ventilation or ECMO
Treatment

JAKi, SOC
Trial Participants

402

Brasilia

COVID-19 status

Confirmed
Outcome

NA
Treatment

Alternative therapy, SOC
Trial Participants

100

Brasilia

COVID-19 status

NA
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

1000

Brasilia

COVID-19 status

Confirmed
Outcome

NA
Treatment

HCQ, LPV/r, LPV/r + IFN, Remdesivir, SOC
Trial Participants

10000

Brasilia

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

100

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Organ Failure or Dysfunction (SOFA), Renal Outcome (Unspecified)
Treatment

SGLT2, SOC
Trial Participants

900

Brasilia

COVID-19 status

Healthy
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

2000

Brasilia

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospital Discharge, Respiratory Rate, Hypoxia
Treatment

Other
Trial Participants

42

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Serious Adverse Events
Treatment

Monoclonal antibody, SOC
Trial Participants

1360

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cardiac Outcome (Unspecified)
Treatment

Anticoagulants, SOC
Trial Participants

3000

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, Treatment-emergent Adverse Events
Treatment

Other, SOC
Trial Participants

410

Brasilia

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospitalization, Adverse Events, C-Reactive Protein, Renal Outcome (Unspecified)
Treatment

Alternative therapy, SOC
Trial Participants

120

Brasilia

COVID-19 status

Confirmed
Outcome

NA
Treatment

SOC, TCZ
Trial Participants

129

Brasilia

COVID-19 status

Healthy
Outcome

Treatment-emergent Adverse Events
Treatment

Antivirals, SOC
Trial Participants

200

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, ALT, Bilirubin
Treatment

mAb, SOC
Trial Participants

270

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, Treatment-emergent Adverse Events, Serious Adverse Events, C-Reactive Protein, IL-6, White Blood Cell Count, Lymphocyte Count, D-Dimer
Treatment

Other, SOC
Trial Participants

68

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, C-Reactive Protein, Ferritin, Lymphocyte Count, SpO2
Treatment

Acalabrutinib, SOC
Trial Participants

177

Brasilia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, SpO2
Treatment

Other, SOC
Trial Participants

1034

Brasilia

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, Respiratory Rate, Hypoxemia
Treatment

Sarilumab, SOC
Trial Participants

420

Brasilia

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Hospitalization
Treatment

HCQ, HCQ + LPV/r, LPV/r, SOC
Trial Participants

1968

Brescia

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospitalization, Adverse Events, Radiographic Findings
Treatment

Radiation therapy
Trial Participants

30

Brescia

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Brescia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Brescia

COVID-19 status

Confirmed
Outcome

Hospitalization
Treatment

Anticoagulants
Trial Participants

300

Bristol

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Clinical Improvement Score (Any), Serious Adverse Events
Treatment

Other, SOC
Trial Participants

150

Bristol

COVID-19 status

Healthy
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

1090

British Columbia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events
Treatment

LPV/r, SOC
Trial Participants

2900

British Columbia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization
Treatment

HCQ, SOC
Trial Participants

70

British Columbia

COVID-19 status

Healthy
Outcome

Adverse Events, Platelet Count, Radiographic Findings
Treatment

Vaccine
Trial Participants

20

British Columbia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

British Columbia

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Organ Failure or Dysfunction (SOFA), Adverse Events, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

ARBs, SOC
Trial Participants

1372

British Columbia

COVID-19 status

Confirmed
Outcome

NA
Treatment

Non-invasive respiratory support, SOC
Trial Participants

50

British Columbia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Adverse Events, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

Plasma based therapy, SOC
Trial Participants

100

British Columbia

COVID-19 status

Confirmed Or Suspected
Outcome

Viral Load or Clearance
Treatment

Hygeine, SOC
Trial Participants

81

British Columbia

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6
Treatment

Non-invasive respiratory support
Trial Participants

200

British Columbia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

Plasma based therapy, SOC
Trial Participants

1200

British Columbia

COVID-19 status

Healthy
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Non-invasive Ventilation, Cough, Fever, Other Mild Symptoms, Adverse Events, Quality of Life, Distress
Treatment

LPV/r, SOC
Trial Participants

1220

Brussels

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Labor Absenteeism, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Organ Failure or Dysfunction (SOFA), Serious Adverse Events, C-Reactive Protein, Ferritin, IL-1, IL-6, Radiographic Findings, Hypoxia
Treatment

Anakinra, Anakinra + Siltuximab, Anakinra + TCZ, Siltuximab, SOC, TCZ
Trial Participants

342

Brussels

COVID-19 status

Confirmed
Outcome

PaO2-FiO2
Treatment

Cytokine removal, SOC
Trial Participants

24

Brussels

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Platelet Count, Hemoglobin, Prothrombin, Electrolytes, INR, ALT, AST, Bilirubin, Glucose
Treatment

HCQ, LPV/r, LPV/r + IFN, Remdesivir, SOC
Trial Participants

3100

Brussels

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Brussels

COVID-19 status

Confirmed Or Suspected
Outcome

ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Deep Vein Thrombosis or Pulmonary Embolism, Serious Adverse Events, IL-1, IL-2, IL-6, IL-7, IL-8, IL-10, Tumor Necrosis Factor (Any), Interferon (Any), Angiotensins, PaO2-FiO2, Radiographic Findings
Treatment

Antihypertensive, SOC
Trial Participants

60

Brussels

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO
Treatment

Plasma based therapy, SOC
Trial Participants

483

Brussels

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

Other, SOC
Trial Participants

310

Brussels

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, D-Dimer, Troponin
Treatment

Other, SOC
Trial Participants

1034

Brussels

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, Ferritin, IL-2, IL-7, Tumor Necrosis Factor (Any), Granulocyte Stimulaiting Factor, Interferon (Any), MCP-1, MIP-1, White Blood Cell Count, Lymphocyte Count, PaO2-FiO2, SpO2, Radiographic Findings
Treatment

Other, SOC
Trial Participants

NA

Brussels

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

NA
Trial Participants

NA

Brussels

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, IL-6, Tumor Necrosis Factor (Any), D-Dimer, Angiotensins, ACE, ECG, SpO2
Treatment

Other, SOC
Trial Participants

465

Brussels

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Labor Absenteeism, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Organ Failure or Dysfunction (SOFA), C-Reactive Protein, Ferritin, IL-1, IL-6, PaO2-FiO2, Radiographic Findings, Hypoxia
Treatment

Siltuximab, TCZ
Trial Participants

NA

Brussels

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Brussels

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Labor Absenteeism, Fever, SpO2, Respiratory Rate
Treatment

Other, SOC
Trial Participants

230

Brussels

COVID-19 status

Confirmed
Outcome

Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, IL-6, Tumor Necrosis Factor (Any), D-Dimer, Antibodies, PaO2-FiO2
Treatment

HCQ, SOC
Trial Participants

8

Brussels

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance, Other Mild Symptoms, Adverse Events, Serious Adverse Events
Treatment

HCQ
Trial Participants

NA

Brussels

COVID-19 status

Healthy
Outcome

Serious Adverse Events
Treatment

SOC, Vaccine
Trial Participants

1045

Brussels

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Organ Failure or Dysfunction (SOFA), Adverse Events, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

ARBs, SOC
Trial Participants

1372

Brussels

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, D-Dimer, PaO2-FiO2, Radiographic Findings, Hypoxia, Distress
Treatment

Other, SOC
Trial Participants

81

Brussels

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

300

Brussels

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, Ferritin, D-Dimer, Procalcitonin, ECG
Treatment

Immunomodulators
Trial Participants

NA

Brussels

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, C-Reactive Protein, Respiratory Rate, Radiographic Findings
Treatment

SOC, TCZ
Trial Participants

60

Brussels

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Lymphocyte Count, Neutrophils, Platelet Count, Hemoglobin, Creatinine Phosphokinase, eGFR, Troponin, ALT, AST, Bilirubin, Glucose, ECG, 6-Minute Walking Distance, Radiographic Findings, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

AZT, SOC
Trial Participants

NA

Brussels

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO, Fever, Other Mild Symptoms, Adverse Events, Respiratory Rate
Treatment

Other, SOC
Trial Participants

190

Brussels

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Serious or Seconday Infections, Adverse Events, C-Reactive Protein, Ferritin, Monocyte Count, Lymphocyte Count, D-Dimer, CD4, CD8, Radiographic Findings
Treatment

Other, SOC
Trial Participants

200

Brussels

COVID-19 status

Confirmed
Outcome

Pneumonia or ARDS
Treatment

Stem cells
Trial Participants

20

Brussels

COVID-19 status

NA
Outcome

Adverse Events, IgG, IgM or IgA, Antibodies
Treatment

Vaccine
Trial Participants

260

Brussels

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Hyper-Inflammation, Adverse Events, C-Reactive Protein, Ferritin, IL-1, IL-6, Tumor Necrosis Factor (Any), Lymphocyte Count, Platelet Count, Hemoglobin, D-Dimer, eGFR, Troponin, Fibrinogen, ALT, AST, Albumin, Bilirubin, Glucose, LDH, Radiographic Findings, Cardiac Outcome (Unspecified)
Treatment

Anticoagulants + Anakinra + Other, SOC
Trial Participants

NA

Brussels

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Labor Absenteeism, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Organ Failure or Dysfunction (SOFA), C-Reactive Protein, Ferritin, D-Dimer, Procalcitonin, Blood Gas, PaO2-FiO2, SpO2, Radiographic Findings, Hypoxia, Cardiac Outcome (Unspecified)
Treatment

Immunomodulators, SOC
Trial Participants

NA

Brussels

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Adverse Events, Serious Adverse Events, PaO2-FiO2
Treatment

Other
Trial Participants

80

Brussels

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

300

Brussels

COVID-19 status

Confirmed
Outcome

Mortality, Serious Adverse Events, Coagulation Test
Treatment

Other, SOC
Trial Participants

60

Brussels

COVID-19 status

Healthy
Outcome

Serious Adverse Events, Antibodies
Treatment

SOC, Vaccine
Trial Participants

284

Brussels

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, SpO2
Treatment

Other, SOC
Trial Participants

1034

Bucharest

COVID-19 status

Confirmed
Outcome

NA
Treatment

FPV, SOC
Trial Participants

256

Bucharest

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, PaO2-FiO2, SpO2, Quality of Life
Treatment

Other, SOC
Trial Participants

682

Bucharest

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB, SOC
Trial Participants

2104

Bucharest

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB
Trial Participants

2970

Bucharest

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO, Fever, Other Mild Symptoms, Adverse Events, Respiratory Rate
Treatment

Other, SOC
Trial Participants

190

Bucharest

COVID-19 status

Confirmed
Outcome

NA
Treatment

Other, SOC
Trial Participants

222

Budapest

COVID-19 status

Healthy
Outcome

ICU Admission, Hospitalization, Other Mild Symptoms
Treatment

Education, Psychological therapy
Trial Participants

7576

Budapest

COVID-19 status

Confirmed
Outcome

Hospital Discharge
Treatment

Other, SOC
Trial Participants

120

Budapest

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, Quality of Life
Treatment

Other, SOC
Trial Participants

140

Budapest

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Labor Absenteeism, Fever
Treatment

SOC, Vaccine
Trial Participants

NA

Budapest

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Other Mild Symptoms, Bilirubin
Treatment

Plasma based therapy
Trial Participants

20

Buenos Aires

COVID-19 status

Confirmed
Outcome

Mortality, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Distress
Treatment

Non-invasive respiratory support, SOC
Trial Participants

80

Buenos Aires

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Serious Adverse Events, C-Reactive Protein, Ferritin, Lymphocyte Count, PaO2-FiO2
Treatment

Acalabrutinib, SOC
Trial Participants

163

Buenos Aires

COVID-19 status

Healthy
Outcome

Serious Adverse Events, Antibodies
Treatment

SOC, Vaccine
Trial Participants

3000

Buenos Aires

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Buenos Aires

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Organ Failure or Dysfunction (SOFA), Adverse Events, Lymphocyte Count
Treatment

NSAIDs
Trial Participants

40

Buenos Aires

COVID-19 status

Confirmed
Outcome

NA
Treatment

Plasma based therapy
Trial Participants

200

Buenos Aires

COVID-19 status

Confirmed
Outcome

NA
Treatment

Igs, SOC
Trial Participants

242

Buenos Aires

COVID-19 status

NA
Outcome

Serious Adverse Events
Treatment

SOC, Vaccine
Trial Participants

43998

Buenos Aires

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Buenos Aires

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge
Treatment

Other, SOC
Trial Participants

140

Buenos Aires

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, Troponin, LDH, Urine Sample
Treatment

Antihypertensive, SOC
Trial Participants

400

Buenos Aires

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA)
Treatment

SOC, Vitamins
Trial Participants

1264

Buenos Aires

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events, Ferritin, D-Dimer, Antibodies
Treatment

Plasma based therapy, SOC
Trial Participants

333

Buenos Aires

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA)
Treatment

Plasma-based therapy, SOC
Trial Participants

36

Buenos Aires

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Buenos Aires

COVID-19 status

Confirmed
Outcome

NA
Treatment

Antivirals, SOC
Trial Participants

135

Buenos Aires

COVID-19 status

Confirmed
Outcome

NA
Treatment

Dexamethasone, SOC
Trial Participants

284

Buenos Aires

COVID-19 status

Healthy
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

60000

Buenos Aires

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Invasive Mechanical Ventilation or ECMO
Treatment

Device
Trial Participants

50

Buenos Aires

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO
Treatment

Colchicine, SOC
Trial Participants

2500

Buenos Aires

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ, LPV/r, Remdesivir, SOC
Trial Participants

7000

Buenos Aires

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, Quality of Life
Treatment

Other, SOC
Trial Participants

140

Buenos Aires

COVID-19 status

Healthy
Outcome

NA
Treatment

NRTIs, SOC
Trial Participants

1378

Buenos Aires

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Adverse Events, Antibodies
Treatment

Ivermectin, SOC
Trial Participants

45

Buenos Aires

COVID-19 status

NA
Outcome

ICU Admission, Invasive Mechanical Ventilation or ECMO
Treatment

JAKi, SOC
Trial Participants

402

Buenos Aires

COVID-19 status

Confirmed
Outcome

NA
Treatment

HCQ, LPV/r, LPV/r + IFN, Remdesivir, SOC
Trial Participants

10000

Buenos Aires

COVID-19 status

Confirmed
Outcome

Respiratory Rate
Treatment

Plasma based therapy, SOC
Trial Participants

210

Buenos Aires

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

40051

Buenos Aires

COVID-19 status

Healthy
Outcome

NA
Treatment

Other, SOC
Trial Participants

400

Buenos Aires

COVID-19 status

Confirmed
Outcome

Mortality, Treatment-emergent Adverse Events, Serious Adverse Events, C-Reactive Protein, IL-6, White Blood Cell Count, Lymphocyte Count, D-Dimer
Treatment

Other, SOC
Trial Participants

68

Buenos Aires

COVID-19 status

Suspected
Outcome

Invasive Mechanical Ventilation or ECMO
Treatment

Anticoagulants
Trial Participants

200

Buenos Aires

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, C-Reactive Protein, Ferritin, Lymphocyte Count, SpO2
Treatment

Acalabrutinib, SOC
Trial Participants

177

Buenos Aires

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, Respiratory Rate, Hypoxemia
Treatment

Sarilumab, SOC
Trial Participants

420

Burgos

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events
Treatment

TCZ
Trial Participants

500

Burgos

COVID-19 status

Healthy
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6
Treatment

HCQ, HCQ + NRTIs, NRTIs, SOC
Trial Participants

4000

Bursa

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Serious Adverse Events, IgG, IgM or IgA, Antibodies
Treatment

SOC, Vaccine
Trial Participants

13000

Cairo

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance
Treatment

Ivermectin, SOC
Trial Participants

100

Cairo

COVID-19 status

Confirmed
Outcome

NA
Treatment

Ivermectin + Antivirals, SOC
Trial Participants

100

Cairo

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any)
Treatment

Other, SOC
Trial Participants

150

Cairo

COVID-19 status

Confirmed
Outcome

Hospitalization, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Adverse Events
Treatment

Alternative therapy, SOC
Trial Participants

50

Cairo

COVID-19 status

NA
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Other Mild Symptoms
Treatment

Other, SOC
Trial Participants

300

Cairo

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, C-Reactive Protein, IL-1, IL-6, Tumor Necrosis Factor (Any), Interferon (Any), Lymphocyte Count, Erythrocyte Sedimentation Rate, D-Dimer
Treatment

Hormone therapy, Hormone therapy + Other, SOC
Trial Participants

160

Cairo

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Distress
Treatment

Anticoagulants
Trial Participants

50

Cairo

COVID-19 status

Confirmed
Outcome

NA
Treatment

Ivermectin, SOC
Trial Participants

100

Cairo

COVID-19 status

Healthy
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

45000

Cairo

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Fever, Adverse Events, C-Reactive Protein, Ferritin, IL-1, IL-6, IL-10, Tumor Necrosis Factor (Any), Platelet Count, Erythrocyte Sedimentation Rate, D-Dimer, Prothrombin, ALT, AST, Albumin, Bilirubin, IgG, IgM or IgA, Blood Urea Nitrogen, Blood Pressure, SpO2, Respiratory Rate, Radiographic Findings
Treatment

Nutrition, SOC
Trial Participants

516

Cairo

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance
Treatment

FPV, SOC
Trial Participants

90

Cairo

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Adverse Events
Treatment

Other, SOC
Trial Participants

40

Cairo

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, Ferritin, IL-6, D-Dimer, Procalcitonin
Treatment

Plasma based therapy
Trial Participants

10

Cairo

COVID-19 status

Confirmed
Outcome

NA
Treatment

Other
Trial Participants

180

Cairo

COVID-19 status

NA
Outcome

Viral Load or Clearance
Treatment

HCQ
Trial Participants

200

Cairo

COVID-19 status

Confirmed
Outcome

NA
Treatment

Plasma based therapy, Plasma based therapy + Other, SOC
Trial Participants

15

Cairo

COVID-19 status

Confirmed
Outcome

NA
Treatment

Other, SOC
Trial Participants

200

Cairo

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ + AZT, SOC
Trial Participants

4000

Cairo

COVID-19 status

NA
Outcome

LDH
Treatment

Other, SOC
Trial Participants

100

Cairo

COVID-19 status

Resolved
Outcome

NA
Treatment

Corticosteroids, SOC
Trial Participants

100

Cairo

COVID-19 status

NA
Outcome

Viral Load or Clearance, Radiographic Findings
Treatment

Antihypertensive, SOC
Trial Participants

60

Cairo

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any)
Treatment

Antivirals, DAA, SOC
Trial Participants

240

Cairo

COVID-19 status

NA
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

200

Cairo

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

Other, SOC
Trial Participants

200

Cairo

COVID-19 status

Confirmed
Outcome

NA
Treatment

Other, SOC
Trial Participants

100

Cairo

COVID-19 status

Confirmed
Outcome

Hospitalization, Distress
Treatment

Dexamethasone
Trial Participants

450

Cairo

COVID-19 status

Confirmed
Outcome

Pneumonia or ARDS
Treatment

DAA, SOC
Trial Participants

50

Cairo

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Cough
Treatment

HCQ, SOC
Trial Participants

40

Cairo

COVID-19 status

Confirmed
Outcome

NA
Treatment

SOC, Stem cells
Trial Participants

100

Cairo

COVID-19 status

Confirmed
Outcome

NA
Treatment

Antivirals + AZT, Ivermectin + Antivirals, Ivermectin + Antivirals + AZT, Ivermectin + HCQ
Trial Participants

80

Cairo

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Clinical Improvement Score (Any), Viral Load or Clearance, Anti SARS-COV-2 Titers, C-Reactive Protein, IL-1, IL-6, Interferon (Any), Erythrocyte Sedimentation Rate, D-Dimer
Treatment

Other, SOC
Trial Participants

1000

Cairo

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance
Treatment

Antivirals, HCQ, Ivermectin
Trial Participants

300

Cairo

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

HCQ, Ivermectin + Docycline
Trial Participants

200

Cairo

COVID-19 status

Confirmed
Outcome

Mortality, IL-1, Tumor Necrosis Factor (Any), Respiratory Rate
Treatment

Alternative therapy, SOC
Trial Participants

100

Cairo

COVID-19 status

Confirmed
Outcome

NA
Treatment

Other, SOC
Trial Participants

360

Cairo

COVID-19 status

Confirmed
Outcome

NA
Treatment

DAA, DAA + Antiviral, SOC
Trial Participants

60

Cairo

COVID-19 status

Confirmed
Outcome

NA
Treatment

HCQ + Antivirals, SOC
Trial Participants

100

Cairo

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Fever, Radiographic Findings
Treatment

FPV, SOC
Trial Participants

100

Cairo

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization
Treatment

DAA, Oseltamivir + HCQ + AZT
Trial Participants

250

Cairo

COVID-19 status

Confirmed
Outcome

NA
Treatment

Plasma based therapy, SOC
Trial Participants

30

Cairo

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Fever, Dyspnea
Treatment

HCQ + AZT, Other
Trial Participants

60

Cairo

COVID-19 status

NA
Outcome

Viral Load or Clearance
Treatment

Other
Trial Participants

100

Cairo

COVID-19 status

NA
Outcome

Mortality, ICU Admission, C-Reactive Protein, Ferritin, IL-1, IL-6, Tumor Necrosis Factor (Any), Interferon (Any), Lymphocyte Count, Erythrocyte Sedimentation Rate, D-Dimer
Treatment

Other
Trial Participants

56

Cairo

COVID-19 status

NA
Outcome

Blood Gas, Blood Pressure, Heart Rate, SpO2, Respiratory Rate, Blood pH
Treatment

Non-invasive respiratory support, SOC
Trial Participants

60

Cairo

COVID-19 status

NA
Outcome

Hospitalization, Cough, Fever, Dyspnea, Other Mild Symptoms, Treatment-emergent Adverse Events
Treatment

NA
Trial Participants

120

Cairo

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

HCQ, HCQ + Zinc
Trial Participants

200

Cairo

COVID-19 status

NA
Outcome

Mortality, Ferritin, IL-6, Tumor Necrosis Factor (Any), Platelet Count, Prothrombin, INR, Respiratory Rate
Treatment

Ivermectin + Antivirals, Non-invasive respiratory support
Trial Participants

100

Cairo

COVID-19 status

Confirmed
Outcome

Fever
Treatment

Other, SOC
Trial Participants

24

Cairo

COVID-19 status

NA
Outcome

Mortality, Viral Load or Clearance, Ferritin, IL-6, Tumor Necrosis Factor (Any), Prothrombin, PaO2-FiO2, Respiratory Rate
Treatment

HCQ + Antivirals, SOC
Trial Participants

100

Cairo

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Viral Load or Clearance, Pneumonia or ARDS, Fever, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, IL-6, IL-8, Tumor Necrosis Factor (Any), PAI-1, von Wildebrandt Factor, Lymphocyte Count, Angiotensins, ACE, ACE-II, Surfactant Factor Protein, SRAGE, PaO2-FiO2, Radiographic Findings
Treatment

Other, SOC
Trial Participants

24

Cairo

COVID-19 status

Confirmed
Outcome

NA
Treatment

Alternative therapy, SOC
Trial Participants

60

Cairo

COVID-19 status

NA
Outcome

Hospitalization, Viral Load or Clearance, Cough, Fever, Dyspnea, Other Mild Symptoms
Treatment

SOC, Vaccine
Trial Participants

200

Cairo

COVID-19 status

Healthy
Outcome

Cough, Fever, Dyspnea, Other Mild Symptoms
Treatment

Ivermectin, SOC
Trial Participants

340

Cairo

COVID-19 status

Confirmed, Suspected Or Healthy
Outcome

NA
Treatment

Nutrition, SOC
Trial Participants

60

Cairo

COVID-19 status

Confirmed
Outcome

Mortality, Viral Load or Clearance, Fever, Radiographic Findings
Treatment

Nutrition, SOC
Trial Participants

1000

Cairo

COVID-19 status

Healthy
Outcome

NA
Treatment

Other
Trial Participants

200

Cairo

COVID-19 status

Confirmed
Outcome

Hospitalization
Treatment

Plasma based therapy, SOC
Trial Participants

67

Cairo

COVID-19 status

Confirmed
Outcome

PaO2-FiO2
Treatment

Anticoagulants, SOC
Trial Participants

100

Cairo

COVID-19 status

Healthy
Outcome

Cough, Fever
Treatment

SOC, Vaccine
Trial Participants

200

Cairo

COVID-19 status

Healthy
Outcome

Viral Load or Clearance
Treatment

SOC, Vaccine
Trial Participants

900

Cairo

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Fever, Radiographic Findings
Treatment

Plasma based therapy
Trial Participants

20

California

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Fever, Dyspnea, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6, Platelet Count, Erythrocyte Sedimentation Rate, D-Dimer, Creatinine Phosphokinase, Troponin, Procalcitonin, LDH, SpO2, Respiratory Rate, Hypoxemia
Treatment

Other, SOC
Trial Participants

100

California

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO
Treatment

Antihypertensive, SOC
Trial Participants

160

California

COVID-19 status

Healthy
Outcome

Antibodies
Treatment

Vaccine
Trial Participants

25

California

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Treatment-emergent Adverse Events, Weight, Height or BMI
Treatment

Remdesivir, SOC
Trial Participants

1230

California

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Adverse Events
Treatment

Razuprotafib, SOC
Trial Participants

180

California

COVID-19 status

Confirmed
Outcome

Adverse Events, Antibodies
Treatment

Monoclonal antibody, SOC
Trial Participants

24

California

COVID-19 status

NA
Outcome

NA
Treatment

mAb
Trial Participants

NA

California

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB, SOC
Trial Participants

2104

California

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Deep Vein Thrombosis or Pulmonary Embolism, Quality of Life, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

Plasma based therapy, SOC
Trial Participants

1000

California

COVID-19 status

NA
Outcome

Viral Load or Clearance
Treatment

DHODH inhibitor, SOC
Trial Participants

100

California

COVID-19 status

Confirmed
Outcome

NA
Treatment

Cardiosphere-Derived Cells, SOC
Trial Participants

60

California

COVID-19 status

Healthy
Outcome

Mortality, Serious Adverse Events, Interferon (Any), Antibodies
Treatment

SOC, Vaccine
Trial Participants

6578

California

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, Remdesivir + JAKi
Trial Participants

1034

California

COVID-19 status

Healthy
Outcome

Labor Absenteeism, Serious Adverse Events
Treatment

Nutrition
Trial Participants

500

California

COVID-19 status

Confirmed
Outcome

Adverse Events, IL-1, IL-6, Radiographic Findings
Treatment

Other, SOC
Trial Participants

60

California

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any)
Treatment

mAb, SOC
Trial Participants

573

California

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Treatment-emergent Adverse Events, Serious Adverse Events, Radiographic Findings
Treatment

PDE4 + SOC, SOC
Trial Participants

700

California

COVID-19 status

Confirmed
Outcome

Adverse Events, C-Reactive Protein, Ferritin, Platelet Count, D-Dimer, Electrolytes
Treatment

Ivermectin + Doxycycline + Zinc + Vitamins, Vitamins + Zinc
Trial Participants

300

California

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB
Trial Participants

2970

California

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Adverse Events
Treatment

Other, SOC
Trial Participants

24

California

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, PaO2-FiO2
Treatment

Acalabrutinib, SOC
Trial Participants

61

California

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Radiographic Findings
Treatment

NA
Trial Participants

600

California

COVID-19 status

Healthy
Outcome

Viral Load or Clearance, Cough, Fever, Dyspnea, Other Mild Symptoms, Adverse Events, Serious Adverse Events
Treatment

HCQ + Vitamins + Zinc, SOC
Trial Participants

600

California

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

California

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, SpO2
Treatment

Other, SOC
Trial Participants

160

California

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, PaO2-FiO2, Radiographic Findings, Hypoxia
Treatment

Inhaled solution, SOC
Trial Participants

144

California

COVID-19 status

Confirmed
Outcome

Adverse Events, White Blood Cell Count, Lymphocyte Count, Platelet Count, Hemoglobin
Treatment

Other, SOC
Trial Participants

30

California

COVID-19 status

NA
Outcome

NA
Treatment

Plasma based therapy
Trial Participants

NA

California

COVID-19 status

Confirmed
Outcome

Hospitalization, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1450

California

COVID-19 status

Healthy
Outcome

NA
Treatment

HCQ, Vitamins
Trial Participants

829

California

COVID-19 status

Healthy
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance
Treatment

SOC, Vaccine
Trial Participants

1800

California

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

52

California

COVID-19 status

NA
Outcome

Mortality
Treatment

Plasma based therapy
Trial Participants

60

California

COVID-19 status

NA
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Organ Failure or Dysfunction (SOFA), Adverse Events
Treatment

Natural Killer Cells, SOC
Trial Participants

86

California

COVID-19 status

Confirmed
Outcome

NA
Treatment

Other
Trial Participants

18

California

COVID-19 status

NA
Outcome

Mortality, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1300

California

COVID-19 status

Confirmed
Outcome

Treatment-emergent Adverse Events, Serious Adverse Events
Treatment

Stem cells
Trial Participants

9

California

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

California

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Visits or Returns to Emergency Department, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, D-Dimer, Troponin, Cardiac Outcome (Unspecified)
Treatment

Colchicine, SOC
Trial Participants

150

California

COVID-19 status

Confirmed
Outcome

Hospitalization, Serious Adverse Events
Treatment

Anticoagulants, SOC
Trial Participants

600

California

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events, PaO2-FiO2
Treatment

mAb, SOC
Trial Participants

300

California

COVID-19 status

Confirmed
Outcome

ECG, SpO2
Treatment

Respiratory support
Trial Participants

50

California

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, Ferritin, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Troponin, Fibrinogen, INR, ALT, AST, Albumin, Bilirubin, Glucose, LDH, IgG, IgM or IgA, Blood Urea Nitrogen, Blood Pressure, SpO2, Radiographic Findings
Treatment

Plasma based therapy, SOC
Trial Participants

208

California

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Viral Load or Clearance
Treatment

Non-invasive respiratory support, SOC
Trial Participants

500

California

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Fever, Adverse Events, Antibodies, SpO2
Treatment

Other, SOC
Trial Participants

2000

California

COVID-19 status

NA
Outcome

Mortality, ICU Admission
Treatment

ACEi, SOC
Trial Participants

560

California

COVID-19 status

Confirmed
Outcome

Fever
Treatment

Antiretroviral + Dexamethasone, Other, Other + Antiretroviral, Other + Dexamethasone
Trial Participants

525

California

COVID-19 status

Confirmed Or Healthy
Outcome

Serious Adverse Events, Antibodies
Treatment

Plasma based therapy
Trial Participants

30

California

COVID-19 status

Confirmed
Outcome

Platelet Count, ALT, AST, Albumin, Bilirubin, Glucose, Blood Urea Nitrogen
Treatment

HCQ + AZT, HCQ + AZT + LPV/r
Trial Participants

200

California

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO, Fever, Other Mild Symptoms, Adverse Events, Respiratory Rate
Treatment

Other, SOC
Trial Participants

190

California

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

California

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance
Treatment

Hygiene
Trial Participants

150

California

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA)
Treatment

mAb, SOC
Trial Participants

390

California

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, ECG, SpO2
Treatment

Other, SOC
Trial Participants

150

California

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Fever, Serious Adverse Events, Respiratory Rate, Radiographic Findings, Hypoxemia
Treatment

Other, SOC
Trial Participants

24

California

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, Bilirubin
Treatment

Remdesivir
Trial Participants

52

California

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Visits or Returns to Emergency Department
Treatment

Anticoagulants, SOC
Trial Participants

4000

California

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ, SOC
Trial Participants

479

California

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance, Non-invasive Ventilation, Cough, Fever, Dyspnea, Treatment-emergent Adverse Events, Respiratory Rate
Treatment

Other, SOC
Trial Participants

380

California

COVID-19 status

Confirmed
Outcome

Mortality, Serious Adverse Events
Treatment

Other, SOC
Trial Participants

60

California

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, Ferritin, LDH
Treatment

Other, SOC
Trial Participants

230

California

COVID-19 status

NA
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6
Treatment

NA
Trial Participants

200

California

COVID-19 status

Healthy
Outcome

IgG, IgM or IgA
Treatment

Vaccine
Trial Participants

175

California

COVID-19 status

Confirmed
Outcome

Mortality, Organ Failure or Dysfunction (SOFA), Serious Adverse Events, Antibodies
Treatment

Remdesivir, Remdesivir + Other
Trial Participants

10000

California

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Fever
Treatment

Hormone therapy, SOC
Trial Participants

198

California

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Adverse Events, C-Reactive Protein
Treatment

Other, SOC
Trial Participants

400

California

COVID-19 status

Confirmed
Outcome

Blood Gas, Blood Pressure, Heart Rate, SpO2, Respiratory Rate
Treatment

Non-invasive respiratory support
Trial Participants

30

California

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

120

California

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

40051

California

COVID-19 status

NA
Outcome

Viral Load or Clearance, Fever, Adverse Events, Anti SARS-COV-2 Titers
Treatment

Hygiene
Trial Participants

45

California

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any)
Treatment

Plasma-based therapy, SOC
Trial Participants

96

California

COVID-19 status

Confirmed
Outcome

NA
Treatment

Other, SOC
Trial Participants

40

California

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Non-invasive Ventilation
Treatment

mAb, SOC
Trial Participants

17

California

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, White Blood Cell Count, Monocyte Count, Lymphocyte Count, Neutrophils, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, SOC
Trial Participants

1062

California

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO
Treatment

Plasma based therapy, SOC
Trial Participants

50

California

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Serious Adverse Events
Treatment

Monoclonal antibody, SOC
Trial Participants

1360

California

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Hospital Discharge, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea
Treatment

Plasma based therapy, SOC
Trial Participants

500

California

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

California

COVID-19 status

NA
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Adverse Events
Treatment

HCQ, HCQ + AZT, SOC
Trial Participants

20

California

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, C-Reactive Protein, IL-6, White Blood Cell Count, Platelet Count, Hemoglobin, ALT, AST, Bilirubin, Respiratory Rate, Hypoxemia
Treatment

Sarilumab, SOC
Trial Participants

1912

California

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events
Treatment

Other, SOC
Trial Participants

46

California

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, Ferritin, Platelet Count, Hemoglobin, D-Dimer, Troponin, Fibrinogen, INR, ALT, AST, Bilirubin
Treatment

Remdesivir, Remdesivir + mAb
Trial Participants

200

California

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Serious Adverse Events, Antibodies
Treatment

Plasma based therapy, SOC
Trial Participants

1344

California

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, INR, ALT, AST, Bilirubin
Treatment

Remdesivir, Remdesivir + IFN
Trial Participants

969

California

COVID-19 status

Confirmed
Outcome

Mortality, Treatment-emergent Adverse Events
Treatment

Other, SOC
Trial Participants

410

California

COVID-19 status

NA
Outcome

ICU Admission, Hospitalization, Clinical Improvement Score (Any), Fever, Dyspnea, Other Mild Symptoms
Treatment

Plasma based therapy, SOC
Trial Participants

600

California

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, ALT, Bilirubin
Treatment

mAb, SOC
Trial Participants

270

California

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Organ Failure or Dysfunction (SOFA), Adverse Events
Treatment

JAKi, SOC
Trial Participants

500

California

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Serious Adverse Events
Treatment

Stem cells
Trial Participants

20

California

COVID-19 status

NA
Outcome

Viral Load or Clearance, Treatment-emergent Adverse Events, Serious Adverse Events, Antibodies
Treatment

mAb, SOC
Trial Participants

50

California

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

Icatibant + Remdesivir, Other + Remdesivir, PDE4 inhibitor + Remdesivir, Remdesivir, VE-PTP inhibitor + Remdesivir
Trial Participants

1500

California

COVID-19 status

Confirmed
Outcome

Antibodies
Treatment

Other, SOC
Trial Participants

120

California

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Adverse Events, Natural Killer Cell Count, CD4, CD8, SpO2, Radiographic Findings
Treatment

mAb, SOC
Trial Participants

86

California

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, PaO2-FiO2, Blood pH
Treatment

Colchicine, SOC
Trial Participants

6000

California

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Treatment-emergent Adverse Events, IgG, IgM or IgA
Treatment

Other
Trial Participants

60

California

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, IL-6
Treatment

Other, SOC
Trial Participants

100

Callao

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Serious Adverse Events
Treatment

Monoclonal antibody, SOC
Trial Participants

1360

Callao

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

40051

Cambridgeshire

COVID-19 status

Healthy
Outcome

Mortality
Treatment

HCQ, SOC
Trial Participants

1500

Cambridgeshire

COVID-19 status

Suspected
Outcome

Mortality, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Adverse Events, Renal Outcome (Unspecified)
Treatment

JAKi, mAb, SOC
Trial Participants

1167

Cambridgeshire

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, Ferritin, IL-6, Lymphocyte Count, D-Dimer, LDH, Renal Outcome (Unspecified)
Treatment

Other, SGLT2 + Other, SOC
Trial Participants

1407

Canberra

COVID-19 status

Healthy
Outcome

NA
Treatment

HCQ, SOC
Trial Participants

2250

Canberra

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Adverse Events
Treatment

Device
Trial Participants

20

Canberra

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, PaO2-FiO2
Treatment

SOC, Stem cells
Trial Participants

40

Canberra

COVID-19 status

Healthy
Outcome

Serious Adverse Events, Antibodies
Treatment

SOC, Vaccine
Trial Participants

216

Canberra

COVID-19 status

Healthy
Outcome

NA
Treatment

Immunomodulators, SOC
Trial Participants

1000

Canberra

COVID-19 status

NA
Outcome

Mortality, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, PaO2-FiO2
Treatment

SOC, Zinc
Trial Participants

160

Canberra

COVID-19 status

NA
Outcome

Viral Load or Clearance, Other Mild Symptoms, Serious or Seconday Infections, Anti SARS-COV-2 Titers
Treatment

Immunomodulators, SOC
Trial Participants

1000

Canberra

COVID-19 status

Confirmed Or Suspected
Outcome

NA
Treatment

Anticoagulants, SOC
Trial Participants

206

Canberra

COVID-19 status

Confirmed
Outcome

NA
Treatment

SOC, TCZ
Trial Participants

150

Canberra

COVID-19 status

Confirmed Or Suspected
Outcome

ICU Admission, Fever, Treatment-emergent Adverse Events, Blood Gas, PaO2-FiO2
Treatment

SOC, Stem cells
Trial Participants

24

Canberra

COVID-19 status

Confirmed Or Healthy
Outcome

Depression, Anxiety
Treatment

Psychological therapy + Nutrition + Exercise
Trial Participants

40

Canberra

COVID-19 status

Healthy
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

3468

Canberra

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, PaO2-FiO2, SpO2, Quality of Life
Treatment

Other, SOC
Trial Participants

682

Canberra

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Labor Absenteeism, Fever, SpO2, Respiratory Rate
Treatment

Other, SOC
Trial Participants

230

Canberra

COVID-19 status

NA
Outcome

Other Mild Symptoms
Treatment

Other
Trial Participants

100

Canberra

COVID-19 status

NA
Outcome

Viral Load or Clearance
Treatment

Hygiene
Trial Participants

20

Canberra

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Secondary CoViD-19 Re-infection, Invasive Mechanical Ventilation or ECMO, Other Mild Symptoms, Adverse Events, Anti SARS-COV-2 Titers
Treatment

Stem cells
Trial Participants

24

Canberra

COVID-19 status

Confirmed
Outcome

SpO2
Treatment

Positioning, SOC
Trial Participants

20

Canberra

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Adverse Events, Blood Pressure, Radiographic Findings
Treatment

ARBs, SOC
Trial Participants

36

Canberra

COVID-19 status

NA
Outcome

Adverse Events, IgG, IgM or IgA, Antibodies
Treatment

SOC, Vaccine
Trial Participants

1419

Canberra

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

300

Canberra

COVID-19 status

Healthy
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Labor Absenteeism, Cough, Fever, Dyspnea, Other Mild Symptoms
Treatment

HCQ
Trial Participants

680

Canberra

COVID-19 status

Confirmed
Outcome

NA
Treatment

HCQ, LPV/r, LPV/r + HCQ
Trial Participants

2500

Canberra

COVID-19 status

Confirmed
Outcome

Non-invasive Ventilation
Treatment

HCQ + LPV/r, HCQ + LPV/r + Plasma based therapy, LPV/r, LPV/r + Plasma based therapy, Plasma based therapy, SOC
Trial Participants

2400

Canberra

COVID-19 status

Confirmed Or Suspected
Outcome

Blood Gas, PaO2-FiO2
Treatment

Other, SOC
Trial Participants

160

Canberra

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality
Treatment

HCQ, SOC
Trial Participants

400

Canberra

COVID-19 status

Healthy
Outcome

Adverse Events
Treatment

SOC, Vaccine
Trial Participants

12

Canberra

COVID-19 status

Confirmed
Outcome

Serious Adverse Events
Treatment

Other + Alternative therapy
Trial Participants

30

Canberra

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ + Zinc + Vitamins + AZT
Trial Participants

200

Canberra

COVID-19 status

Confirmed
Outcome

NA
Treatment

FPV, SOC
Trial Participants

190

Canberra

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

300

Cantabria

COVID-19 status

Confirmed
Outcome

Hospitalization
Treatment

Colchicine, SOC
Trial Participants

954

Cantabria

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events
Treatment

TCZ
Trial Participants

500

Catania

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Adverse Events, C-Reactive Protein, IL-6, Lymphocyte Count, PaO2-FiO2, Radiographic Findings
Treatment

TCZ
Trial Participants

400

Catania

COVID-19 status

Confirmed
Outcome

Hospitalization
Treatment

Anticoagulants
Trial Participants

300

Catanzaro

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Alternative therapy, SOC
Trial Participants

120

Catanzaro

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Lymphocyte Count
Treatment

Plasma based therapy, SOC
Trial Participants

400

Ceara

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB
Trial Participants

2970

Celje

COVID-19 status

NA
Outcome

ICU Admission, Hospitalization, Hospital Discharge, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ, HCQ + Other
Trial Participants

90

Chandigarh

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Non-invasive Ventilation, Organ Failure or Dysfunction (SOFA)
Treatment

Other, SOC
Trial Participants

40

Chandigarh

COVID-19 status

Healthy
Outcome

NA
Treatment

HCQ, SOC
Trial Participants

325

Chandigarh

COVID-19 status

NA
Outcome

Serious or Seconday Infections, Adverse Events, Serious Adverse Events
Treatment

Other
Trial Participants

4000

Chandigarh

COVID-19 status

NA
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Other Mild Symptoms, Adverse Events, Serious Adverse Events
Treatment

Other, SOC
Trial Participants

480

Chelyabinsk

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, Quality of Life
Treatment

Other, SOC
Trial Participants

140

Cher

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Fever, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, C-Reactive Protein, IL-6, CK-MB, Procalcitonin, Radiographic Findings
Treatment

HCQ, SOC
Trial Participants

259

Chhattisgarh

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Non-invasive Ventilation, Organ Failure or Dysfunction (SOFA)
Treatment

Other, SOC
Trial Participants

40

Chiba

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Chiba

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Organ Failure or Dysfunction (SOFA), Adverse Events, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

ARBs, SOC
Trial Participants

1372

Chieti

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Chieti

COVID-19 status

Confirmed
Outcome

NA
Treatment

Plasma based therapy, SOC
Trial Participants

182

Chisinau

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB
Trial Participants

2970

Chisinau

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO, Fever, Other Mild Symptoms, Adverse Events, Respiratory Rate
Treatment

Other, SOC
Trial Participants

190

Chisinau

COVID-19 status

Confirmed
Outcome

NA
Treatment

Other, SOC
Trial Participants

222

Chongqing

COVID-19 status

Confirmed
Outcome

Mortality, Viral Load or Clearance, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events
Treatment

Antivirals + IFN, Antivirals + LPV/r + IFN, LPV/r + IFN
Trial Participants

108

Chongqing

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO
Treatment

Corticosteroids, SOC
Trial Participants

48

Chongqing

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Fever, C-Reactive Protein, IL-6, Lymphocyte Count, PaO2-FiO2, SpO2
Treatment

Other, SOC
Trial Participants

368

Chongqing

COVID-19 status

Healthy
Outcome

Adverse Events
Treatment

SOC, Vaccine
Trial Participants

50

Chongqing

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Pneumonia or ARDS, Adverse Events, Treatment-emergent Adverse Events
Treatment

Natural Killer Cells
Trial Participants

90

Chongqing

COVID-19 status

Confirmed
Outcome

ICU Admission, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea
Treatment

IFN + Other, LPV/r + IFN, Umifenovir + IFN
Trial Participants

60

City

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, Remdesivir + JAKi
Trial Participants

1034

City

COVID-19 status

Confirmed
Outcome

Hospitalization, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1450

City

COVID-19 status

NA
Outcome

Mortality, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1300

City

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, White Blood Cell Count, Monocyte Count, Lymphocyte Count, Neutrophils, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, SOC
Trial Participants

1062

Ciudad De Buenos Aires

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Serious Adverse Events, C-Reactive Protein, Ferritin, Lymphocyte Count, PaO2-FiO2
Treatment

Acalabrutinib, SOC
Trial Participants

163

Ciudad De Buenos Aires

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, Troponin, LDH, Urine Sample
Treatment

Antihypertensive, SOC
Trial Participants

400

Ciudad De Buenos Aires

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Ciudad De Buenos Aires

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Adverse Events, Antibodies
Treatment

Ivermectin, SOC
Trial Participants

45

Ciudad Real

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Creatinine Phosphokinase, ALT, AST, Bilirubin, ECG
Treatment

Other
Trial Participants

46

Ciudad Real

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events
Treatment

TCZ
Trial Participants

500

Colorado

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Serious Adverse Events, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Plasma based therapy, SOC
Trial Participants

702

Colorado

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Treatment-emergent Adverse Events, Weight, Height or BMI
Treatment

Remdesivir, SOC
Trial Participants

1230

Colorado

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB, SOC
Trial Participants

2104

Colorado

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Deep Vein Thrombosis or Pulmonary Embolism, Quality of Life, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

Plasma based therapy, SOC
Trial Participants

1000

Colorado

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, Remdesivir + JAKi
Trial Participants

1034

Colorado

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB
Trial Participants

2970

Colorado

COVID-19 status

NA
Outcome

NA
Treatment

Plasma based therapy
Trial Participants

NA

Colorado

COVID-19 status

Confirmed
Outcome

Mortality, SpO2, Patient Positioning
Treatment

Positioning
Trial Participants

100

Colorado

COVID-19 status

Confirmed
Outcome

Adverse Events
Treatment

Plasma based therapy, SOC
Trial Participants

40

Colorado

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Other Mild Symptoms, Quality of Life
Treatment

HCQ, LPV/r, SOC
Trial Participants

600

Colorado

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Fever, Adverse Events, Antibodies, SpO2
Treatment

Other, SOC
Trial Participants

2000

Colorado

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Colorado

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Visits or Returns to Emergency Department
Treatment

Anticoagulants, SOC
Trial Participants

4000

Colorado

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ, SOC
Trial Participants

479

Colorado

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Organ Failure or Dysfunction (SOFA), Adverse Events, C-Reactive Protein, Quality of Life, Renal Outcome (Unspecified)
Treatment

Dexamethasone, SOC
Trial Participants

90

Colorado

COVID-19 status

Confirmed
Outcome

Mortality, Organ Failure or Dysfunction (SOFA), Serious Adverse Events, Antibodies
Treatment

Remdesivir, Remdesivir + Other
Trial Participants

10000

Colorado

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

40051

Colorado

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, White Blood Cell Count, Monocyte Count, Lymphocyte Count, Neutrophils, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, SOC
Trial Participants

1062

Colorado

COVID-19 status

Confirmed
Outcome

Mortality, Pneumonia or ARDS, Blood Pressure, Renal Outcome (Unspecified)
Treatment

Other, SOC
Trial Participants

100

Colorado

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Colorado

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, C-Reactive Protein, IL-6, White Blood Cell Count, Platelet Count, Hemoglobin, ALT, AST, Bilirubin, Respiratory Rate, Hypoxemia
Treatment

Sarilumab, SOC
Trial Participants

1912

Colorado

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events, White Blood Cell Count, Hemoglobin, Creatinine Phosphokinase, Prothrombin, ALT, Bilirubin, Glucose
Treatment

JAKi
Trial Participants

80

Colorado

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6, White Blood Cell Count, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose, Renal Outcome (Unspecified)
Treatment

NA
Trial Participants

80

Colorado

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, INR, ALT, AST, Bilirubin
Treatment

Remdesivir, Remdesivir + IFN
Trial Participants

969

Colorado

COVID-19 status

NA
Outcome

ICU Admission, Hospitalization, Clinical Improvement Score (Any), Fever, Dyspnea, Other Mild Symptoms
Treatment

Plasma based therapy, SOC
Trial Participants

600

Colorado

COVID-19 status

Confirmed
Outcome

Adverse Events
Treatment

Other, SOC
Trial Participants

10

Colorado

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

Icatibant + Remdesivir, Other + Remdesivir, PDE4 inhibitor + Remdesivir, Remdesivir, VE-PTP inhibitor + Remdesivir
Trial Participants

1500

Conakry

COVID-19 status

Confirmed
Outcome

Mortality, SpO2
Treatment

HCQ, LPV/r, SOC
Trial Participants

3000

Connecticut

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, SpO2
Treatment

Other, SOC
Trial Participants

142

Connecticut

COVID-19 status

NA
Outcome

Mortality, Viral Load or Clearance, Antibodies
Treatment

Plasma based therapy
Trial Participants

48

Connecticut

COVID-19 status

Confirmed
Outcome

D-Dimer
Treatment

Other, SOC
Trial Participants

200

Connecticut

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Adverse Events
Treatment

DHODH inhibitor, SOC
Trial Participants

24

Connecticut

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Adverse Events
Treatment

JAKi, SOC
Trial Participants

60

Connecticut

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Connecticut

COVID-19 status

NA
Outcome

Hospitalization
Treatment

Other, SOC
Trial Participants

60

Connecticut

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

40051

Connecticut

COVID-19 status

NA
Outcome

Clinical Improvement Score (Any)
Treatment

Plasma based therapy, SOC
Trial Participants

300

Connecticut

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Hospital Discharge, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea
Treatment

Plasma based therapy, SOC
Trial Participants

500

Connecticut

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Connecticut

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, C-Reactive Protein, IL-6, White Blood Cell Count, Platelet Count, Hemoglobin, ALT, AST, Bilirubin, Respiratory Rate, Hypoxemia
Treatment

Sarilumab, SOC
Trial Participants

1912

Connecticut

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Serious Adverse Events, Antibodies
Treatment

Plasma based therapy, SOC
Trial Participants

1344

Connecticut

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA)
Treatment

Nutrition, SOC
Trial Participants

1500

Connecticut

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

Icatibant + Remdesivir, Other + Remdesivir, PDE4 inhibitor + Remdesivir, Remdesivir, VE-PTP inhibitor + Remdesivir
Trial Participants

1500

Connecticut

COVID-19 status

NA
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Fever, Other Mild Symptoms
Treatment

Other, SOC
Trial Participants

114

Connecticut

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Adverse Events, Natural Killer Cell Count, CD4, CD8, SpO2, Radiographic Findings
Treatment

mAb, SOC
Trial Participants

86

Connecticut

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, IL-6
Treatment

Other, SOC
Trial Participants

100

Copenhagen

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Quality of Life
Treatment

Corticosteroids, SOC
Trial Participants

1000

Copenhagen

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Treatment-emergent Adverse Events, Weight, Height or BMI
Treatment

Remdesivir, SOC
Trial Participants

1230

Copenhagen

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Visits or Returns to Emergency Department, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, PaO2-FiO2, Blood pH, Quality of Life
Treatment

AZT, HCQ, SOC
Trial Participants

NA

Copenhagen

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, C-Reactive Protein
Treatment

Sarilumab, TCZ
Trial Participants

NA

Copenhagen

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, Remdesivir + JAKi
Trial Participants

1034

Copenhagen

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Shock, Quality of Life, Renal Outcome (Unspecified)
Treatment

Corticosteroids, SOC
Trial Participants

NA

Copenhagen

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events, White Blood Cell Count, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose, Renal Outcome (Unspecified)
Treatment

Remdesivir, SOC
Trial Participants

440

Copenhagen

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Labor Absenteeism, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Hyper-Inflammation, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Deep Vein Thrombosis or Pulmonary Embolism, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6, Tumor Necrosis Factor (Any), White Blood Cell Count, D-Dimer, Creatinine Phosphokinase, Bilirubin, Glucose, Antibodies, PaO2-FiO2, Radiographic Findings, Lung Inflamation, Hypoxemia, Quality of Life
Treatment

SOC, TCZ
Trial Participants

450

Copenhagen

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Fever, Adverse Events, Serious Adverse Events, PaO2-FiO2
Treatment

NA
Trial Participants

350

Copenhagen

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein
Treatment

Sarilumab, SOC, TCZ
Trial Participants

20

Copenhagen

COVID-19 status

Confirmed
Outcome

Hospital Discharge
Treatment

Other, SOC
Trial Participants

120

Copenhagen

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Viral Load or Clearance, Labor Absenteeism, Fever, Other Mild Symptoms
Treatment

SOC, Vaccine
Trial Participants

1500

Copenhagen

COVID-19 status

Confirmed
Outcome

NA
Treatment

Respiratory support, SOC
Trial Participants

400

Copenhagen

COVID-19 status

NA
Outcome

Mortality, Viral Load or Clearance, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Coagulation Test, Bilirubin, PaO2-FiO2, Renal Outcome (Unspecified)
Treatment

Other
Trial Participants

NA

Copenhagen

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events
Treatment

HCQ, JAKi, Sarilumab, SOC
Trial Participants

1500

Copenhagen

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

80

Copenhagen

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ, SOC
Trial Participants

NA

Copenhagen

COVID-19 status

Healthy
Outcome

Viral Load or Clearance, Antibodies
Treatment

NA
Trial Participants

6000

Copenhagen

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

NA
Trial Participants

1100

Copenhagen

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Renal Outcome (Unspecified)
Treatment

Positioning
Trial Participants

150

Copenhagen

COVID-19 status

NA
Outcome

Mortality
Treatment

JAKi
Trial Participants

NA

Copenhagen

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Visits or Returns to Emergency Department, Viral Load or Clearance
Treatment

HCQ, SOC
Trial Participants

NA

Copenhagen

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, LDH
Treatment

Antihypertensive, SOC
Trial Participants

200

Copenhagen

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Blood Gas, Blood pH
Treatment

HCQ + AZT, SOC
Trial Participants

226

Copenhagen

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Labor Absenteeism, Fever
Treatment

SOC, Vaccine
Trial Participants

NA

Copenhagen

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, Quality of Life
Treatment

Other, SOC
Trial Participants

140

Copenhagen

COVID-19 status

Confirmed
Outcome

Hospitalization, Non-invasive Ventilation
Treatment

Remdesivir, SOC
Trial Participants

400

Copenhagen

COVID-19 status

Confirmed
Outcome

Mortality, Organ Failure or Dysfunction (SOFA), Serious Adverse Events, Antibodies
Treatment

Remdesivir, Remdesivir + Other
Trial Participants

10000

Copenhagen

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, White Blood Cell Count, Monocyte Count, Lymphocyte Count, Neutrophils, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, SOC
Trial Participants

1062

Copenhagen

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

580

Copenhagen

COVID-19 status

Confirmed
Outcome

NA
Treatment

SOC, Vitamins
Trial Participants

100

Cordoba

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Cordoba

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Cordoba

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Dyspnea, Adverse Events
Treatment

SOC, Vitamins
Trial Participants

1008

Cornwall

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Corrientes

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, Renal Outcome (Unspecified)
Treatment

Ivermectin, SOC
Trial Participants

500

Corrientes

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Cosenza

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Lymphocyte Count
Treatment

Plasma based therapy, SOC
Trial Participants

400

Cosenza

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Adverse Events, C-Reactive Protein, IL-6, Lymphocyte Count, PaO2-FiO2, Radiographic Findings
Treatment

TCZ
Trial Participants

400

Cremona

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Cremona

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Cremona

COVID-19 status

Confirmed
Outcome

Hospitalization
Treatment

Anticoagulants
Trial Participants

300

Cross River

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any)
Treatment

Nutrition, SOC
Trial Participants

90

Cuenca

COVID-19 status

Healthy
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6
Treatment

HCQ, HCQ + NRTIs, NRTIs, SOC
Trial Participants

4000

Cumbria

COVID-19 status

Healthy
Outcome

Viral Load or Clearance, Pneumonia or ARDS
Treatment

HCQ, SOC
Trial Participants

40000

Cundinamarca

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Adverse Events, C-Reactive Protein, Ferritin, Lymphocyte Count, D-Dimer, Troponin, Procalcitonin, LDH, PaO2-FiO2
Treatment

Plasma based therapy, SOC
Trial Participants

236

Cundinamarca

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, IgG, IgM or IgA
Treatment

Plasma based therapy
Trial Participants

10

Cundinamarca

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), IL-6, Hemoglobin, D-Dimer, Procalcitonin, AST, Bilirubin, Antibodies, Radiographic Findings
Treatment

Plasma based therapy, SOC
Trial Participants

60

Cundinamarca

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, IgG, IgM or IgA
Treatment

HCQ + AZT, Plasma based therapy + HCQ + AZT
Trial Participants

92

Cundinamarca

COVID-19 status

Confirmed
Outcome

Hospitalization, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1450

Cundinamarca

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ + AZT, SOC
Trial Participants

4000

Daegu

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Daegu

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Dagestan

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

mAb, SOC
Trial Participants

206

Dakar

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance, Organ Failure or Dysfunction (SOFA), Serious Adverse Events
Treatment

HCQ, HCQ + AZT
Trial Participants

186

Dakar

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance
Treatment

HCQ + AZT, Zinc
Trial Participants

384

Delaware

COVID-19 status

Confirmed
Outcome

C-Reactive Protein, IL-6
Treatment

Other, SOC
Trial Participants

64

Delhi

COVID-19 status

Healthy
Outcome

NA
Treatment

Alternative therapy, SOC
Trial Participants

140

Delhi

COVID-19 status

Healthy
Outcome

NA
Treatment

Alternative therapy, SOC
Trial Participants

50000

Delhi

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Non-invasive Ventilation, Organ Failure or Dysfunction (SOFA)
Treatment

Other, SOC
Trial Participants

40

Delhi

COVID-19 status

Confirmed
Outcome

Mortality, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Fever, Dyspnea, Other Mild Symptoms, Organ Failure or Dysfunction (SOFA), Adverse Events, PaO2-FiO2
Treatment

Plasma based therapy, SOC
Trial Participants

100

Delhi

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Serious Adverse Events, C-Reactive Protein, Ferritin, Lymphocyte Count, PaO2-FiO2
Treatment

Acalabrutinib, SOC
Trial Participants

163

Delhi

COVID-19 status

Confirmed
Outcome

NA
Treatment

Alternative therapy
Trial Participants

50

Delhi

COVID-19 status

Healthy
Outcome

NA
Treatment

Alternative therapy, SOC
Trial Participants

200

Delhi

COVID-19 status

Confirmed
Outcome

NA
Treatment

Alternative therapy
Trial Participants

40

Delhi

COVID-19 status

Healthy
Outcome

NA
Treatment

Alternative therapy, SOC
Trial Participants

40000

Delhi

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any)
Treatment

Plasma based therapy, SOC
Trial Participants

400

Delhi

COVID-19 status

Confirmed
Outcome

NA
Treatment

Radiation therapy
Trial Participants

10

Delhi

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Delhi

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance
Treatment

Ivermectin, SOC
Trial Participants

120

Delhi

COVID-19 status

Healthy
Outcome

NA
Treatment

Exercise + Alternative therapy, SOC
Trial Participants

452

Delhi

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

Alternative therapy, SOC
Trial Participants

300

Delhi

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Delhi

COVID-19 status

Confirmed Or Suspected
Outcome

Hospital Discharge, Invasive Mechanical Ventilation or ECMO
Treatment

Positioning
Trial Participants

20

Delhi

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, Quality of Life
Treatment

Other, SOC
Trial Participants

140

Delhi

COVID-19 status

Healthy
Outcome

Antibodies
Treatment

Psychological therapy, SOC
Trial Participants

250

Delhi

COVID-19 status

Healthy
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

800

Delhi

COVID-19 status

Healthy
Outcome

NA
Treatment

Alternative therapy
Trial Participants

500

Delhi

COVID-19 status

Healthy
Outcome

NA
Treatment

Alternative therapy + Hygiene+ Exercise + Psychological therapy
Trial Participants

425

Delhi

COVID-19 status

Confirmed
Outcome

NA
Treatment

ARBs, SOC
Trial Participants

605

Delhi

COVID-19 status

Confirmed
Outcome

ICU Admission, Invasive Mechanical Ventilation or ECMO
Treatment

Non-invasive respiratory support
Trial Participants

100

Delhi

COVID-19 status

Confirmed
Outcome

NA
Treatment

Alternative therapy, SOC
Trial Participants

96

Delhi

COVID-19 status

Confirmed Or Healthy
Outcome

Viral Load or Clearance
Treatment

Alternative therapy, SOC
Trial Participants

61000

Delhi

COVID-19 status

Confirmed
Outcome

Mortality, Pneumonia or ARDS, PaO2-FiO2
Treatment

Plasma based therapy, SOC
Trial Participants

452

Delhi

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance
Treatment

Ivermectin, SOC
Trial Participants

50

Delhi

COVID-19 status

Confirmed
Outcome

Mortality, Pneumonia or ARDS, PaO2-FiO2
Treatment

Plasma based therapy, SOC
Trial Participants

100

Delhi

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

Alternative therapy, SOC
Trial Participants

100

Delhi

COVID-19 status

Suspected
Outcome

NA
Treatment

Alternative therapy
Trial Participants

10000

Devon

COVID-19 status

Healthy
Outcome

Viral Load or Clearance, Pneumonia or ARDS
Treatment

HCQ, SOC
Trial Participants

40000

Dhaka

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any)
Treatment

Ivermectin + Antibiotics, SOC
Trial Participants

400

Dhaka

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Remdesivir, SOC
Trial Participants

60

Dhaka

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

Antibiotics, SOC
Trial Participants

94

Dhaka

COVID-19 status

Confirmed
Outcome

Cough, Fever
Treatment

Ivermectin, Ivermectin + Antibiotics, SOC
Trial Participants

72

Dhaka

COVID-19 status

Confirmed
Outcome

Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Colchicine, SOC
Trial Participants

300

Dhaka

COVID-19 status

Confirmed
Outcome

Radiographic Findings
Treatment

FPV, SOC
Trial Participants

50

Dhaka

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

Plasma based therapy, SOC
Trial Participants

20

District Of Columbia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Adverse Events
Treatment

Razuprotafib, SOC
Trial Participants

180

District Of Columbia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB, SOC
Trial Participants

2104

District Of Columbia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, Remdesivir + JAKi
Trial Participants

1034

District Of Columbia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Treatment-emergent Adverse Events, D-Dimer, Antibodies, PaO2-FiO2, SpO2
Treatment

mAb, SOC
Trial Participants

384

District Of Columbia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, PaO2-FiO2
Treatment

Acalabrutinib, SOC
Trial Participants

61

District Of Columbia

COVID-19 status

Confirmed
Outcome

Hospitalization, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1450

District Of Columbia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

52

District Of Columbia

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, Ferritin, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Troponin, Fibrinogen, INR, ALT, AST, Albumin, Bilirubin, Glucose, LDH, IgG, IgM or IgA, Blood Urea Nitrogen, Blood Pressure, SpO2, Radiographic Findings
Treatment

Plasma based therapy, SOC
Trial Participants

208

District Of Columbia

COVID-19 status

Confirmed
Outcome

Fever
Treatment

Antiretroviral + Dexamethasone, Other, Other + Antiretroviral, Other + Dexamethasone
Trial Participants

525

District Of Columbia

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO, Fever, Other Mild Symptoms, Adverse Events, Respiratory Rate
Treatment

Other, SOC
Trial Participants

190

District Of Columbia

COVID-19 status

Confirmed Or Suspected
Outcome

Hospitalization
Treatment

mAb, SOC
Trial Participants

376

District Of Columbia

COVID-19 status

Confirmed
Outcome

Mortality, Organ Failure or Dysfunction (SOFA), Serious Adverse Events, Antibodies
Treatment

Remdesivir, Remdesivir + Other
Trial Participants

10000

District Of Columbia

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Hospital Discharge, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea
Treatment

Plasma based therapy, SOC
Trial Participants

500

District Of Columbia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, C-Reactive Protein, IL-6, White Blood Cell Count, Platelet Count, Hemoglobin, ALT, AST, Bilirubin, Respiratory Rate, Hypoxemia
Treatment

Sarilumab, SOC
Trial Participants

1912

District Of Columbia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events
Treatment

Other, SOC
Trial Participants

46

District Of Columbia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Organ Failure or Dysfunction (SOFA), Adverse Events
Treatment

JAKi, SOC
Trial Participants

500

Distrito Federal

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Treatment-emergent Adverse Events, D-Dimer, Antibodies, PaO2-FiO2
Treatment

HCQ, SOC
Trial Participants

630

Distrito Federal

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA)
Treatment

Dexamethasone, SOC
Trial Participants

299

Distrito Federal

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Quality of Life
Treatment

HCQ, HCQ + AZT
Trial Participants

440

Distrito Federal

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Organ Failure or Dysfunction (SOFA), Renal Outcome (Unspecified)
Treatment

SGLT2, SOC
Trial Participants

900

Djibouti

COVID-19 status

NA
Outcome

NA
Treatment

Plasma based therapy
Trial Participants

NA

Dodoma

COVID-19 status

Confirmed
Outcome

Mortality, SpO2
Treatment

HCQ, LPV/r, SOC
Trial Participants

3000

Doha

COVID-19 status

Confirmed Or Suspected
Outcome

NA
Treatment

Vasodilators
Trial Participants

40

Doha

COVID-19 status

Healthy
Outcome

NA
Treatment

HCQ, SOC
Trial Participants

500

Doha

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance
Treatment

HCQ, HCQ + AZT, SOC
Trial Participants

456

Doha

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ, LPV/r, Remdesivir, SOC
Trial Participants

7000

Doha

COVID-19 status

Confirmed
Outcome

NA
Treatment

Device, SOC
Trial Participants

20

Doha

COVID-19 status

Confirmed
Outcome

PaO2-FiO2, Renal Outcome (Unspecified)
Treatment

Anticoagulants, SOC
Trial Participants

100

Doha

COVID-19 status

Confirmed
Outcome

NA
Treatment

HCQ, LPV/r, LPV/r + IFN, Remdesivir, SOC
Trial Participants

10000

Dublin

COVID-19 status

Confirmed
Outcome

Mortality, Viral Load or Clearance, Non-invasive Ventilation, C-Reactive Protein, Ferritin, IL-6, D-Dimer, LDH, Radiographic Findings, Shock
Treatment

SOC, TCZ
Trial Participants

90

Dublin

COVID-19 status

Healthy
Outcome

NA
Treatment

HCQ, SOC
Trial Participants

30000

Dublin

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, IL-1, IL-6, IL-8, IL-10, Tumor Necrosis Factor (Any), PaO2-FiO2, Shock, Renal Outcome (Unspecified)
Treatment

Other
Trial Participants

36

Dublin

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Non-invasive Ventilation, PaO2-FiO2
Treatment

HCQ, HCQ + AZT, SOC
Trial Participants

267

Dublin

COVID-19 status

Confirmed
Outcome

NA
Treatment

HCQ, LPV/r, LPV/r + IFN, Remdesivir, SOC
Trial Participants

10000

Dublin

COVID-19 status

NA
Outcome

Invasive Mechanical Ventilation or ECMO, PaO2-FiO2, Respiratory Rate, Patient Positioning
Treatment

Positioning, SOC
Trial Participants

200

Dublin

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Serious Adverse Events, SpO2
Treatment

Other, SOC
Trial Participants

90

Dudley

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Clinical Improvement Score (Any), Serious Adverse Events
Treatment

Other, SOC
Trial Participants

150

Dudley

COVID-19 status

Healthy
Outcome

Viral Load or Clearance, Pneumonia or ARDS
Treatment

HCQ, SOC
Trial Participants

40000

Dundee

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Pneumonia or ARDS
Treatment

AZT, SOC
Trial Participants

800

East Azarbaijan

COVID-19 status

Confirmed
Outcome

Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

30

East Azarbaijan

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

Alternative therapy, SOC
Trial Participants

80

East Azarbaijan

COVID-19 status

Confirmed
Outcome

Organ Failure or Dysfunction (SOFA), Platelet Count, Coagulation Test, Bilirubin, PaO2-FiO2, Renal Outcome (Unspecified)
Treatment

HCQ, HCQ + Raltagravir, HCQ + Raltagravir + IFN
Trial Participants

60

East Azarbaijan

COVID-19 status

Confirmed
Outcome

Hospitalization
Treatment

SOC, Vitamins
Trial Participants

30

East Azarbaijan

COVID-19 status

Confirmed
Outcome

C-Reactive Protein, White Blood Cell Count, Respiratory Rate
Treatment

NA
Trial Participants

60

East Azarbaijan

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

NA
Trial Participants

200

East Azarbaijan

COVID-19 status

NA
Outcome

Viral Load or Clearance
Treatment

Alternative therapy, SOC
Trial Participants

86

East Azarbaijan

COVID-19 status

NA
Outcome

ICU Admission, Hospitalization, Cough, Fever, Dyspnea, Other Mild Symptoms, Adverse Events, Serious Adverse Events, ALT
Treatment

Alternative therapy, SOC
Trial Participants

110

East Azarbaijan

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

60

East Azarbaijan

COVID-19 status

NA
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Radiographic Findings
Treatment

HCQ + LPV/r + Antivirals, Igs + HCQ + LPV/r + Antivirals
Trial Participants

100

East Azarbaijan

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, Radiographic Findings
Treatment

Dialysis
Trial Participants

10

East Azarbaijan

COVID-19 status

NA
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA)
Treatment

Plasma based therapy
Trial Participants

30

East Azarbaijan

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

HCQ + LPV/r, HCQ + LPV/r + Other
Trial Participants

60

East Azarbaijan

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Viral Load or Clearance
Treatment

HCQ, SOC
Trial Participants

500

East Azarbaijan

COVID-19 status

NA
Outcome

Fever, Other Mild Symptoms, C-Reactive Protein, Blood Pressure, Heart Rate, Respiratory Rate, Radiographic Findings
Treatment

Alternative therapy, SOC
Trial Participants

10

East Azarbaijan

COVID-19 status

Healthy
Outcome

NA
Treatment

Alternative therapy, SOC
Trial Participants

300

East Azarbaijan

COVID-19 status

Confirmed
Outcome

C-Reactive Protein
Treatment

Other, SOC
Trial Participants

40

East Azarbaijan

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Hospitalization, Cough, Fever, Dyspnea, Other Mild Symptoms, C-Reactive Protein, White Blood Cell Count, SpO2, Respiratory Rate, Radiographic Findings
Treatment

Alternative therapy, SOC
Trial Participants

80

East Sussex

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, White Blood Cell Count, Monocyte Count, Lymphocyte Count, Neutrophils, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, SOC
Trial Participants

1062

Edinburgh

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Non-invasive Ventilation
Treatment

Other, SOC
Trial Participants

389

Edinburgh

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Edinburgh

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Viral Load or Clearance, Adverse Events, Coagulation Test, SpO2, Renal Outcome (Unspecified)
Treatment

Anticoagulants, Other, SOC
Trial Participants

60

Edinburgh

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Espirito Santo

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Quality of Life
Treatment

HCQ, HCQ + AZT
Trial Participants

440

Espirito Santo

COVID-19 status

Confirmed
Outcome

Mortality, D-Dimer, Troponin
Treatment

Anticoagulants
Trial Participants

600

Essex

COVID-19 status

Healthy
Outcome

Viral Load or Clearance, Pneumonia or ARDS
Treatment

HCQ, SOC
Trial Participants

40000

Fars

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Respiratory Rate
Treatment

NA
Trial Participants

374

Fars

COVID-19 status

Suspected
Outcome

Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Other Mild Symptoms, C-Reactive Protein
Treatment

Alternative therapy, SOC
Trial Participants

60

Fars

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

Corticosteroids + Igs + IFN, HCQ + Antivirals
Trial Participants

105

Fars

COVID-19 status

Healthy
Outcome

NA
Treatment

Vaccine
Trial Participants

130000

Fars

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Fever, SpO2
Treatment

Alternative therapy, SOC
Trial Participants

60

Firenze

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Serious Adverse Events, C-Reactive Protein, Ferritin, Lymphocyte Count, PaO2-FiO2
Treatment

Acalabrutinib, SOC
Trial Participants

163

Florida

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Treatment-emergent Adverse Events
Treatment

Other, SOC
Trial Participants

436

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever
Treatment

Other, SOC
Trial Participants

40

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Serious Adverse Events, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Plasma based therapy, SOC
Trial Participants

702

Florida

COVID-19 status

Confirmed
Outcome

Non-invasive Ventilation, Treatment-emergent Adverse Events, Serious Adverse Events, Lymphocyte Count, Antibodies
Treatment

CD122-preferential IL2 pathway, SOC
Trial Participants

30

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Organ Failure or Dysfunction (SOFA), Adverse Events, C-Reactive Protein, D-Dimer, Radiographic Findings
Treatment

Other, SOC
Trial Participants

20

Florida

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Serious or Seconday Infections, C-Reactive Protein, Ferritin, Lymphocyte Count, D-Dimer, CD4, CD8
Treatment

Other, SOC
Trial Participants

48

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Treatment-emergent Adverse Events, Weight, Height or BMI
Treatment

Remdesivir, SOC
Trial Participants

1230

Florida

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Fever, Organ Failure or Dysfunction (SOFA), SpO2, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

Other, SOC
Trial Participants

252

Florida

COVID-19 status

Confirmed
Outcome

Adverse Events, Antibodies
Treatment

Monoclonal antibody, SOC
Trial Participants

24

Florida

COVID-19 status

NA
Outcome

Mortality, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Treatment-emergent Adverse Events, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, D-Dimer, Troponin, Antibodies
Treatment

SOC, Stem cells
Trial Participants

24

Florida

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Dyspnea, Organ Failure or Dysfunction (SOFA), PaO2-FiO2
Treatment

ARBs
Trial Participants

200

Florida

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB, SOC
Trial Participants

2104

Florida

COVID-19 status

NA
Outcome

Viral Load or Clearance
Treatment

DHODH inhibitor, SOC
Trial Participants

100

Florida

COVID-19 status

Confirmed
Outcome

Hospitalization, Cough, Fever, Dyspnea, Other Mild Symptoms
Treatment

SOC, Vitamins, Vitamins + Zinc, Zinc
Trial Participants

520

Florida

COVID-19 status

NA
Outcome

Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Dyspnea, PaO2-FiO2, 6-Minute Walking Distance
Treatment

Inhaled solution, SOC
Trial Participants

288

Florida

COVID-19 status

Healthy
Outcome

Mortality, Serious Adverse Events, Interferon (Any), Antibodies
Treatment

SOC, Vaccine
Trial Participants

6578

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, Remdesivir + JAKi
Trial Participants

1034

Florida

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB
Trial Participants

2970

Florida

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, PaO2-FiO2
Treatment

Acalabrutinib, SOC
Trial Participants

61

Florida

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Florida

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Serious or Seconday Infections, C-Reactive Protein, Ferritin, Lymphocyte Count, D-Dimer, CD4, CD8
Treatment

Other, SOC
Trial Participants

48

Florida

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, PaO2-FiO2, Radiographic Findings, Hypoxia
Treatment

Inhaled solution, SOC
Trial Participants

144

Florida

COVID-19 status

NA
Outcome

NA
Treatment

Plasma based therapy
Trial Participants

NA

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, Adverse Events, SpO2
Treatment

Merimepodib + Remdesivir, Remdesivir
Trial Participants

80

Florida

COVID-19 status

Confirmed
Outcome

Hospitalization, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1450

Florida

COVID-19 status

Suspected
Outcome

NA
Treatment

Antivirals + Vitamins, Vitamins
Trial Participants

800

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, SpO2
Treatment

Alternative therapy, SOC
Trial Participants

280

Florida

COVID-19 status

Confirmed
Outcome

NA
Treatment

SOC, Vitamins
Trial Participants

160

Florida

COVID-19 status

NA
Outcome

Mortality, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1300

Florida

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Florida

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission
Treatment

SOC, Stem cells
Trial Participants

70

Florida

COVID-19 status

Confirmed
Outcome

Hospitalization, Serious Adverse Events
Treatment

Anticoagulants, SOC
Trial Participants

600

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Adverse Events
Treatment

DHODH inhibitor, SOC
Trial Participants

24

Florida

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events, PaO2-FiO2
Treatment

mAb, SOC
Trial Participants

300

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Viral Load or Clearance
Treatment

Non-invasive respiratory support, SOC
Trial Participants

500

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Fever, Adverse Events, Antibodies, SpO2
Treatment

Other, SOC
Trial Participants

2000

Florida

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Viral Load or Clearance, Pneumonia or ARDS, Organ Failure or Dysfunction (SOFA), Serious Adverse Events, Electrolytes, LDH
Treatment

SOC, Stem cells
Trial Participants

21

Florida

COVID-19 status

Confirmed
Outcome

Fever, Serious Adverse Events, Platelet Count, ALT, AST, Albumin, Bilirubin, Blood Pressure, Heart Rate, SpO2
Treatment

Other, SOC
Trial Participants

300

Florida

COVID-19 status

Confirmed
Outcome

NA
Treatment

Other, SOC
Trial Participants

100

Florida

COVID-19 status

Confirmed
Outcome

Fever
Treatment

Antiretroviral + Dexamethasone, Other, Other + Antiretroviral, Other + Dexamethasone
Trial Participants

525

Florida

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality
Treatment

SOC, Vaccine
Trial Participants

96

Florida

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO, Fever, Other Mild Symptoms, Adverse Events, Respiratory Rate
Treatment

Other, SOC
Trial Participants

190

Florida

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA)
Treatment

mAb, SOC
Trial Participants

390

Florida

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Fever, Serious Adverse Events, Respiratory Rate, Radiographic Findings, Hypoxemia
Treatment

Other, SOC
Trial Participants

24

Florida

COVID-19 status

NA
Outcome

IL-6, Glucose, SpO2
Treatment

DPP-4i, SOC
Trial Participants

20

Florida

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, Bilirubin
Treatment

Remdesivir
Trial Participants

52

Florida

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Visits or Returns to Emergency Department
Treatment

Anticoagulants, SOC
Trial Participants

4000

Florida

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ, SOC
Trial Participants

479

Florida

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, Ferritin, LDH
Treatment

Other, SOC
Trial Participants

230

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Fever
Treatment

Hormone therapy, SOC
Trial Participants

198

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Organ Failure or Dysfunction (SOFA), Serious Adverse Events, Antibodies
Treatment

Remdesivir, Remdesivir + Other
Trial Participants

10000

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, Ferritin, Platelet Count, Hemoglobin, D-Dimer, Troponin, Fibrinogen, INR, ALT, AST, Bilirubin, LDH
Treatment

Remdesivir, Remdesivir + mAb
Trial Participants

200

Florida

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

40051

Florida

COVID-19 status

NA
Outcome

Clinical Improvement Score (Any)
Treatment

Plasma based therapy, SOC
Trial Participants

300

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Serious Adverse Events
Treatment

Monoclonal antibody, SOC
Trial Participants

1360

Florida

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Hospital Discharge, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea
Treatment

Plasma based therapy, SOC
Trial Participants

500

Florida

COVID-19 status

NA
Outcome

Adverse Events, IgG, IgM or IgA, Antibodies
Treatment

Vaccine
Trial Participants

260

Florida

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, C-Reactive Protein, IL-6, White Blood Cell Count, Platelet Count, Hemoglobin, ALT, AST, Bilirubin, Respiratory Rate, Hypoxemia
Treatment

Sarilumab, SOC
Trial Participants

1912

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events
Treatment

Other, SOC
Trial Participants

46

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, Ferritin, Platelet Count, Hemoglobin, D-Dimer, Troponin, Fibrinogen, INR, ALT, AST, Bilirubin
Treatment

Remdesivir, Remdesivir + mAb
Trial Participants

200

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Serious Adverse Events, Antibodies
Treatment

Plasma based therapy, SOC
Trial Participants

1344

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Treatment-emergent Adverse Events
Treatment

Other, SOC
Trial Participants

410

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, INR, ALT, AST, Bilirubin
Treatment

Remdesivir, Remdesivir + IFN
Trial Participants

969

Florida

COVID-19 status

NA
Outcome

ICU Admission, Hospitalization, Clinical Improvement Score (Any), Fever, Dyspnea, Other Mild Symptoms
Treatment

Plasma based therapy, SOC
Trial Participants

600

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Adverse Events
Treatment

Antirheumatic, SOC
Trial Participants

1000

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, ALT, Bilirubin
Treatment

mAb, SOC
Trial Participants

270

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Serious Adverse Events, Antibodies
Treatment

mAb, SOC
Trial Participants

124

Florida

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Organ Failure or Dysfunction (SOFA), Adverse Events
Treatment

JAKi, SOC
Trial Participants

500

Florida

COVID-19 status

NA
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance
Treatment

FPV, SOC
Trial Participants

50

Florida

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, PaO2-FiO2, Blood pH
Treatment

Colchicine, SOC
Trial Participants

6000

Florida

COVID-19 status

NA
Outcome

Hospitalization
Treatment

Anticoagulants, Antihypertensive, SOC
Trial Participants

7000

Florida

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Lymphocyte Count, D-Dimer
Treatment

Immunomodulators, SOC
Trial Participants

243

Foggia

COVID-19 status

Confirmed
Outcome

Hospitalization
Treatment

Anticoagulants
Trial Participants

300

Fujian

COVID-19 status

Resolved
Outcome

Quality of Life
Treatment

Respiratory support
Trial Participants

80

Fujian

COVID-19 status

Confirmed
Outcome

IL-6, Quality of Life, Distress
Treatment

Respiratory support, SOC
Trial Participants

80

Fujian

COVID-19 status

Healthy
Outcome

Quality of Life
Treatment

Respiratory support, SOC
Trial Participants

80

Fujian

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Fever, Serious Adverse Events, Heart Rate, Respiratory Rate
Treatment

HCQ, SOC
Trial Participants

100

Fujian

COVID-19 status

NA
Outcome

C-Reactive Protein, IL-10, Tumor Necrosis Factor (Any), CD4, CD8, Blood Gas, PaO2-FiO2
Treatment

Oseltamivir + Non-invasive respiratory support + Hormone therapy, Stem cells + Oseltamivir + Non-invasive respiratory support + Hormone therapy
Trial Participants

60

Fujian

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Viral Load or Clearance, Fever, Serious Adverse Events, Respiratory Rate
Treatment

HCQ, SOC
Trial Participants

100

Fukuoka

COVID-19 status

NA
Outcome

Serious Adverse Events
Treatment

Vaccine
Trial Participants

256

Galway

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Hospitalization, Non-invasive Ventilation, Troponin
Treatment

Antihypertensive
Trial Participants

2414

Gauteng

COVID-19 status

Healthy
Outcome

NA
Treatment

HCQ, SOC
Trial Participants

30000

Gauteng

COVID-19 status

NA
Outcome

Adverse Events
Treatment

SOC, Vaccine
Trial Participants

2130

Gauteng

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Gauteng

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, Quality of Life
Treatment

Other, SOC
Trial Participants

140

Gauteng

COVID-19 status

NA
Outcome

Viral Load or Clearance, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

40

Gaziantep

COVID-19 status

NA
Outcome

Clinical Improvement Score (Any)
Treatment

Other, SOC
Trial Participants

200

Gaziantep

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Serious Adverse Events, IgG, IgM or IgA, Antibodies
Treatment

SOC, Vaccine
Trial Participants

13000

Gelderland

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Hospitalization, Labor Absenteeism, Fever, Other Mild Symptoms, Anti SARS-COV-2 Titers, IgG, IgM or IgA, Antibodies
Treatment

SOC, Vaccine
Trial Participants

1500

Gelderland

COVID-19 status

Resolved
Outcome

Other Mild Symptoms, 6-Minute Walking Distance
Treatment

Rehabilitation
Trial Participants

40

Georgia

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir + Dexamethasone, Remdesivir + JAKi
Trial Participants

1500

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Fever, Organ Failure or Dysfunction (SOFA), C-Reactive Protein, IL-6, Platelet Count, Hemoglobin, D-Dimer, Prothrombin, Fibrinogen, INR, Albumin, Bilirubin, Blood Urea Nitrogen, Blood Pressure, Heart Rate, Respiratory Rate
Treatment

Plasma based therapy, SOC
Trial Participants

20

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Serious Adverse Events, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Plasma based therapy, SOC
Trial Participants

702

Georgia

COVID-19 status

Confirmed
Outcome

Adverse Events, CD8
Treatment

Vaccine
Trial Participants

32

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Treatment-emergent Adverse Events, Weight, Height or BMI
Treatment

Remdesivir, SOC
Trial Participants

1230

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB, SOC
Trial Participants

2104

Georgia

COVID-19 status

NA
Outcome

Viral Load or Clearance
Treatment

DHODH inhibitor, SOC
Trial Participants

100

Georgia

COVID-19 status

Confirmed
Outcome

Blood Gas, Blood Pressure, Heart Rate, SpO2, Respiratory Rate, Blood pH, Bicarbonates
Treatment

Non-invasive respiratory support, SOC
Trial Participants

2

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, Remdesivir + JAKi
Trial Participants

1034

Georgia

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Adverse Events
Treatment

Other, SOC
Trial Participants

24

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB
Trial Participants

2970

Georgia

COVID-19 status

NA
Outcome

NA
Treatment

Plasma based therapy
Trial Participants

NA

Georgia

COVID-19 status

Confirmed
Outcome

Hospitalization, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1450

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

52

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events, PaO2-FiO2
Treatment

mAb, SOC
Trial Participants

300

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Fever, Adverse Events, Antibodies, SpO2
Treatment

Other, SOC
Trial Participants

2000

Georgia

COVID-19 status

Confirmed
Outcome

Fever, Serious Adverse Events, Platelet Count, ALT, AST, Albumin, Bilirubin, Blood Pressure, Heart Rate, SpO2
Treatment

Other, SOC
Trial Participants

300

Georgia

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO, Fever, Other Mild Symptoms, Adverse Events, Respiratory Rate
Treatment

Other, SOC
Trial Participants

190

Georgia

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA)
Treatment

mAb, SOC
Trial Participants

390

Georgia

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Fever, Serious Adverse Events, Respiratory Rate, Radiographic Findings, Hypoxemia
Treatment

Other, SOC
Trial Participants

24

Georgia

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Visits or Returns to Emergency Department
Treatment

Anticoagulants, SOC
Trial Participants

4000

Georgia

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance, Non-invasive Ventilation, Cough, Fever, Dyspnea, Treatment-emergent Adverse Events, Respiratory Rate
Treatment

Other, SOC
Trial Participants

380

Georgia

COVID-19 status

Confirmed Or Suspected
Outcome

Hospitalization
Treatment

mAb, SOC
Trial Participants

376

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, Ferritin, LDH
Treatment

Other, SOC
Trial Participants

230

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, Organ Failure or Dysfunction (SOFA), Serious Adverse Events, Antibodies
Treatment

Remdesivir, Remdesivir + Other
Trial Participants

10000

Georgia

COVID-19 status

Confirmed
Outcome

Blood Gas, Blood Pressure, Heart Rate, SpO2, Respiratory Rate
Treatment

Non-invasive respiratory support
Trial Participants

30

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, Ferritin, Platelet Count, Hemoglobin, D-Dimer, Troponin, Fibrinogen, INR, ALT, AST, Bilirubin, LDH
Treatment

Remdesivir, Remdesivir + mAb
Trial Participants

200

Georgia

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

40051

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, White Blood Cell Count, Monocyte Count, Lymphocyte Count, Neutrophils, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, SOC
Trial Participants

1062

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Serious Adverse Events
Treatment

Monoclonal antibody, SOC
Trial Participants

1360

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Serious Adverse Events, Antibodies
Treatment

mAb, SOC
Trial Participants

124

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, C-Reactive Protein, IL-6, White Blood Cell Count, Platelet Count, Hemoglobin, ALT, AST, Bilirubin, Respiratory Rate, Hypoxemia
Treatment

Sarilumab, SOC
Trial Participants

1912

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, Ferritin, Platelet Count, Hemoglobin, D-Dimer, Troponin, Fibrinogen, INR, ALT, AST, Bilirubin
Treatment

Remdesivir, Remdesivir + mAb
Trial Participants

200

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, INR, ALT, AST, Bilirubin
Treatment

Remdesivir, Remdesivir + IFN
Trial Participants

969

Georgia

COVID-19 status

NA
Outcome

ICU Admission, Hospitalization, Clinical Improvement Score (Any), Fever, Dyspnea, Other Mild Symptoms
Treatment

Plasma based therapy, SOC
Trial Participants

600

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, ALT, Bilirubin
Treatment

mAb, SOC
Trial Participants

270

Georgia

COVID-19 status

NA
Outcome

C-Reactive Protein, Ferritin, IL-6, Hemoglobin, D-Dimer, eGFR, Myoglobin, Troponin, Procalcitonin, Fibrinogen, Triglycerides, ALT, AST, Albumin, Bilirubin, LDH, Blood Gas, Blood Pressure, Heart Rate, Radiographic Findings, Blood pH
Treatment

Radiation therapy
Trial Participants

10

Georgia

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization
Treatment

HCQ, SOC
Trial Participants

700

Georgia

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Adverse Events, Natural Killer Cell Count, CD4, CD8, SpO2, Radiographic Findings
Treatment

mAb, SOC
Trial Participants

86

Gerona

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events
Treatment

TCZ
Trial Participants

500

Gibraltar

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), C-Reactive Protein, Troponin
Treatment

Colchicine, SOC
Trial Participants

180

Glasgow

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Glasgow

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Goias

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ + AZT, SOC
Trial Participants

4000

Goias

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Quality of Life
Treatment

HCQ, HCQ + AZT
Trial Participants

440

Golestan

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance
Treatment

NA
Trial Participants

45

Golestan

COVID-19 status

Confirmed
Outcome

NA
Treatment

Alternative therapy, SOC
Trial Participants

60

Golestan

COVID-19 status

Confirmed
Outcome

Platelet Count, Radiographic Findings
Treatment

Alternative therapy, SOC
Trial Participants

50

Granada

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events
Treatment

TCZ
Trial Participants

500

Granada

COVID-19 status

NA
Outcome

ICU Admission, Pneumonia or ARDS, Cough, Other Mild Symptoms
Treatment

Nutrition, SOC
Trial Participants

314

Granada

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Serious Adverse Events
Treatment

Monoclonal antibody, SOC
Trial Participants

1360

Granada

COVID-19 status

Healthy
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6
Treatment

HCQ, HCQ + NRTIs, NRTIs, SOC
Trial Participants

4000

Greater Accra

COVID-19 status

Healthy
Outcome

NA
Treatment

HCQ, SOC
Trial Participants

30000

Greenwich

COVID-19 status

Healthy
Outcome

Viral Load or Clearance, Pneumonia or ARDS
Treatment

HCQ, SOC
Trial Participants

40000

Groningen

COVID-19 status

NA
Outcome

Mortality, ICU Admission
Treatment

Plasma-based therapy
Trial Participants

690

Groningen

COVID-19 status

Confirmed
Outcome

Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, IL-6, Tumor Necrosis Factor (Any), D-Dimer, Antibodies, PaO2-FiO2
Treatment

HCQ, SOC
Trial Participants

8

Groningen

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, Radiographic Findings
Treatment

Plasma based therapy, SOC
Trial Participants

426

Guadalajara

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Creatinine Phosphokinase, ALT, AST, Bilirubin, ECG
Treatment

Other
Trial Participants

46

Guam

COVID-19 status

NA
Outcome

NA
Treatment

Plasma based therapy
Trial Participants

NA

Guangdong

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Other Mild Symptoms, C-Reactive Protein, Creatinine Phosphokinase, CK-MB, eGFR, Myoglobin, Troponin, Procalcitonin, Prothrombin, Fibrinogen, ALT, Albumin, Bilirubin, Quality of Life
Treatment

Non-invasive respiratory support
Trial Participants

440

Guangdong

COVID-19 status

NA
Outcome

Mortality, Viral Load or Clearance, Pneumonia or ARDS, Cough, Fever, Dyspnea, Adverse Events, C-Reactive Protein, CD4, CD8, PaO2-FiO2, Radiographic Findings
Treatment

SOC, Stem cells
Trial Participants

20

Guangdong

COVID-19 status

Confirmed Or Suspected
Outcome

Fever, C-Reactive Protein, Creatinine Phosphokinase, CK-MB, eGFR, Myoglobin, Procalcitonin, ALT, Albumin, Bilirubin, Blood Gas, Radiographic Findings, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

TCM
Trial Participants

72

Guangdong

COVID-19 status

NA
Outcome

Hospitalization, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Fever, Dyspnea, C-Reactive Protein, White Blood Cell Count, CD4, CD8, Renal Outcome (Unspecified)
Treatment

NA
Trial Participants

300

Guangdong

COVID-19 status

Confirmed
Outcome

C-Reactive Protein, IL-17, Lymphocyte Count, Blood Gas
Treatment

SOC, Vaccine
Trial Participants

120

Guangdong

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Pneumonia or ARDS, Cough, Fever, Dyspnea, C-Reactive Protein, White Blood Cell Count, Neutrophils, Hemoglobin, Urine Sample, IgG, IgM or IgA, Blood Urea Nitrogen
Treatment

NA
Trial Participants

100

Guangdong

COVID-19 status

Confirmed
Outcome

NA
Treatment

NA
Trial Participants

60

Guangdong

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Organ Failure or Dysfunction (SOFA), Quality of Life
Treatment

Nutrition, SOC
Trial Participants

80

Guangdong

COVID-19 status

Resolved
Outcome

Dyspnea, Weight, Height or BMI
Treatment

Other, TCM + Other
Trial Participants

150

Guangdong

COVID-19 status

Resolved
Outcome

Other Mild Symptoms
Treatment

SOC, TCM
Trial Participants

144

Guangdong

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospitalization, Viral Load or Clearance, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), C-Reactive Protein, White Blood Cell Count, Creatinine Phosphokinase, CK-MB, eGFR, Myoglobin, Troponin, ALT, Albumin, Bilirubin, IgG, IgM or IgA, PaO2-FiO2, Respiratory Rate, Radiographic Findings
Treatment

SOC, TCM
Trial Participants

400

Guangdong

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Pneumonia or ARDS, Treatment-emergent Adverse Events
Treatment

SOC, TCM
Trial Participants

204

Guangdong

COVID-19 status

Confirmed
Outcome

Pneumonia or ARDS, Cough, Fever, Dyspnea, Other Mild Symptoms, White Blood Cell Count, Erythrocyte Sedimentation Rate, Creatinine Phosphokinase, CK-MB, eGFR, Myoglobin, Troponin, Procalcitonin, Prothrombin, Fibrinogen, Coagulation Test, ALT, Albumin, Bilirubin, Radiographic Findings
Treatment

SOC, TCM
Trial Participants

300

Guangdong

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance
Treatment

Hygiene, SOC
Trial Participants

40

Guangdong

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, Radiographic Findings
Treatment

Vaccine
Trial Participants

100

Guangdong

COVID-19 status

Confirmed
Outcome

NA
Treatment

Anticoagulants, Other
Trial Participants

120

Guangdong

COVID-19 status

Confirmed
Outcome

Mortality, Viral Load or Clearance, Pneumonia or ARDS, ALT
Treatment

IFN + Other, Umifenovir + IFN
Trial Participants

30

Guangdong

COVID-19 status

Confirmed
Outcome

Mortality, Viral Load or Clearance, Pneumonia or ARDS, Cough, Fever, Dyspnea, Other Mild Symptoms, C-Reactive Protein, Erythrocyte Sedimentation Rate
Treatment

SOC, TCM
Trial Participants

120

Guangdong

COVID-19 status

Confirmed
Outcome

Hospitalization, Cough, C-Reactive Protein
Treatment

SOC, TCM
Trial Participants

128

Guangdong

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Treatment-emergent Adverse Events, Radiographic Findings
Treatment

Other, SOC
Trial Participants

40

Guangdong

COVID-19 status

Resolved
Outcome

Clinical Improvement Score (Any), 6-Minute Walking Distance, Quality of Life
Treatment

SOC, TCM
Trial Participants

120

Guangdong

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Cough, Dyspnea, SpO2, Distress
Treatment

Non-invasive respiratory support, SOC
Trial Participants

90

Guangdong

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Pneumonia or ARDS, Cough, Fever, Respiratory Rate
Treatment

Anticoagulants, SOC
Trial Participants

60

Guangdong

COVID-19 status

Confirmed Or Healthy
Outcome

Mortality, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Treatment-emergent Adverse Events, C-Reactive Protein
Treatment

Vaccine
Trial Participants

100

Guangdong

COVID-19 status

Confirmed
Outcome

Mortality, Viral Load or Clearance, Cough, Fever, Dyspnea, Other Mild Symptoms, Serious or Seconday Infections, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events
Treatment

SOC, TCM + Umifenovir
Trial Participants

40

Guangdong

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), C-Reactive Protein, Erythrocyte Sedimentation Rate
Treatment

Nutrition, SOC
Trial Participants

394

Guangdong

COVID-19 status

Confirmed
Outcome

Mortality, Viral Load or Clearance, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Fever, Adverse Events, Serious Adverse Events, Tumor Necrosis Factor (Any), Interferon (Any), Creatinine Phosphokinase, CK-MB, eGFR, Myoglobin, ALT, Bilirubin, Blood Pressure, Heart Rate, PaO2-FiO2, Respiratory Rate, Radiographic Findings
Treatment

LPV/r, SOC, Umifenovir
Trial Participants

86

Guangdong

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Radiographic Findings
Treatment

SOC, Stem cells
Trial Participants

200

Guangdong

COVID-19 status

Confirmed
Outcome

Pneumonia or ARDS, C-Reactive Protein, IL-2, IL-6, Tumor Necrosis Factor (Any), Interferon (Any), Lymphocyte Count, Erythrocyte Sedimentation Rate, D-Dimer, Myoglobin, Procalcitonin, Electrolytes, Glucose, Blood Gas, Renal Outcome (Unspecified)
Treatment

Other, SOC
Trial Participants

60

Guangdong

COVID-19 status

Confirmed
Outcome

Radiographic Findings, Renal Outcome (Unspecified)
Treatment

DAA, FPV
Trial Participants

30

Guangdong

COVID-19 status

Healthy
Outcome

Household Members with CoViD-19
Treatment

SOC, TCM
Trial Participants

828

Guangdong

COVID-19 status

Confirmed
Outcome

SpO2
Treatment

Non-invasive respiratory support
Trial Participants

198

Guangdong

COVID-19 status

Confirmed
Outcome

Mortality, C-Reactive Protein, IL-6, IL-10, Tumor Necrosis Factor (Any), Lymphocyte Count, Neutrophils, Platelet Count, D-Dimer, Myoglobin, Procalcitonin, Prothrombin, Fibrinogen, Coagulation Test, Renal Outcome (Unspecified)
Treatment

HCQ, LPV/r
Trial Participants

112

Guangdong

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance
Treatment

HCQ, LPV/r, LPV/r + HCQ
Trial Participants

205

Guangdong

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, C-Reactive Protein
Treatment

HCQ, SOC
Trial Participants

20

Guangdong

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Radiographic Findings, Renal Outcome (Unspecified)
Treatment

FPV + IFN, IFN, LPV/r + IFN
Trial Participants

90

Guangxi

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Viral Load or Clearance, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events
Treatment

SOC, Vaccine
Trial Participants

60

Guayas

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ + AZT, SOC
Trial Participants

4000

Guizhou

COVID-19 status

Confirmed
Outcome

ICU Admission, PaO2-FiO2, Respiratory Rate
Treatment

Respiratory support
Trial Participants

200

Guizhou

COVID-19 status

Confirmed
Outcome

CK-MB, LDH
Treatment

Other
Trial Participants

200

Gujarat

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any)
Treatment

Alternative therapy, SOC
Trial Participants

200

Gujarat

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ + AZT, SOC
Trial Participants

4000

Gujarat

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Gujarat

COVID-19 status

Confirmed
Outcome

NA
Treatment

Alternative therapy, SOC
Trial Participants

48

Gujarat

COVID-19 status

Confirmed
Outcome

Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Adverse Events, C-Reactive Protein, Ferritin, IL-6, IL-10, Tumor Necrosis Factor (Any)
Treatment

Other, SOC
Trial Participants

106

Gunma

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, C-Reactive Protein
Treatment

FPV
Trial Participants

100

Gunma

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, C-Reactive Protein
Treatment

HCQ + LPV/r, Oseltamivir + HCQ + LPV/r
Trial Participants

50

Gyeonggi

COVID-19 status

Healthy
Outcome

NA
Treatment

Device, Vaccine + Device
Trial Participants

160

Gyeonggi

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Gyeonggi

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, White Blood Cell Count, Monocyte Count, Lymphocyte Count, Neutrophils, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, SOC
Trial Participants

1062

Gyeonggi

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, INR, ALT, AST, Bilirubin
Treatment

Remdesivir, Remdesivir + IFN
Trial Participants

969

Haifa

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Adverse Events
Treatment

HCQ, SOC
Trial Participants

582

Haifa

COVID-19 status

NA
Outcome

Mortality, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1300

Haifa

COVID-19 status

Confirmed
Outcome

ICU Admission, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Adverse Events, SpO2
Treatment

Other, SOC
Trial Participants

50

Haifa

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO
Treatment

Antihypertensive, SOC
Trial Participants

120

Hamadan

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

Other, SOC
Trial Participants

92

Hamadan

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

Corticosteroids, Dexamethasone
Trial Participants

81

Hamburg

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), C-Reactive Protein, IL-6, IL-10, Tumor Necrosis Factor (Any), Procalcitonin, Bicarbonates, Renal Outcome (Unspecified)
Treatment

Cytokine removal, SOC
Trial Participants

24

Hamburg

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, D-Dimer, Troponin
Treatment

Other, SOC
Trial Participants

1034

Hamburg

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, LDH
Treatment

Antihypertensive, SOC
Trial Participants

200

Hamburg

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

Anticoagulants
Trial Participants

172

Hamburg

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Hamburg

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Hamburg

COVID-19 status

NA
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO
Treatment

NA
Trial Participants

220

Hampshire

COVID-19 status

Confirmed, Suspected Or Healthy
Outcome

Viral Load or Clearance
Treatment

Hygiene, SOC
Trial Participants

40

Hanoi

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Pneumonia or ARDS, Fever, Adverse Events
Treatment

HCQ, SOC
Trial Participants

250

Hanoi

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events
Treatment

Plasma based therapy, SOC
Trial Participants

44

Hanoi

COVID-19 status

Confirmed
Outcome

NA
Treatment

Plasma based therapy
Trial Participants

10

Harare

COVID-19 status

Healthy
Outcome

NA
Treatment

HCQ, SOC
Trial Participants

30000

Haryana

COVID-19 status

Healthy
Outcome

Antibodies
Treatment

SOC, Vaccine
Trial Participants

25800

Haryana

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

SOC, TCZ
Trial Participants

180

Haryana

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ + AZT, SOC
Trial Participants

4000

Haryana

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Haryana

COVID-19 status

Confirmed
Outcome

Hospital Discharge
Treatment

Alternative therapy, SOC
Trial Participants

60

Havana

COVID-19 status

NA
Outcome

Viral Load or Clearance, Adverse Events, Serious Adverse Events, C-Reactive Protein, IL-6, Tumor Necrosis Factor (Any), Interferon (Any), Prothrombin, Triglycerides, ALT, Albumin, Bilirubin, Glucose
Treatment

SOC, Vaccine
Trial Participants

80

Havana

COVID-19 status

Confirmed
Outcome

Labor Absenteeism
Treatment

IFN
Trial Participants

120

Havana

COVID-19 status

Healthy
Outcome

NA
Treatment

IFN
Trial Participants

30

Havana

COVID-19 status

Confirmed
Outcome

NA
Treatment

mAb
Trial Participants

80

Havana

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge
Treatment

Other
Trial Participants

16

Havana

COVID-19 status

Healthy
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

115000

Havana

COVID-19 status

Healthy
Outcome

Monocyte Count, Lymphocyte Count, Dendritic Cell Count, CD4, CD8
Treatment

Other
Trial Participants

60

Havana

COVID-19 status

Confirmed
Outcome

NA
Treatment

Other, SOC
Trial Participants

20

Havana

COVID-19 status

Confirmed
Outcome

Cough, Fever, Dyspnea, Other Mild Symptoms
Treatment

HCQ + Antivirals + Inferon, Other + HCQ + Antivirals + Inferon
Trial Participants

32

Havana

COVID-19 status

Confirmed
Outcome

NA
Treatment

Immunomodulators
Trial Participants

NA

Havana

COVID-19 status

Resolved
Outcome

Pneumonia or ARDS
Treatment

Corticosteroids, Stem cells
Trial Participants

20

Hawaii

COVID-19 status

NA
Outcome

NA
Treatment

Plasma based therapy
Trial Participants

NA

Hawaii

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, Ferritin, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Troponin, Fibrinogen, INR, ALT, AST, Albumin, Bilirubin, Glucose, LDH, IgG, IgM or IgA, Blood Urea Nitrogen, Blood Pressure, SpO2, Radiographic Findings
Treatment

Plasma based therapy, SOC
Trial Participants

208

Hawaii

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Hawaii

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

40051

Hawaii

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Hawaii

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, INR, ALT, AST, Bilirubin
Treatment

Remdesivir, Remdesivir + IFN
Trial Participants

969

Hawaii

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO
Treatment

SOC, TCZ
Trial Participants

300

Hawaii

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Pneumonia or ARDS, Non-invasive Ventilation, Heart Rate
Treatment

HCQ, SOC
Trial Participants

17

Hebei

COVID-19 status

Suspected
Outcome

Viral Load or Clearance, Cough, Fever, Other Mild Symptoms, Radiographic Findings
Treatment

SOC, TCM
Trial Participants

240

Hebei

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Cough, Fever, Other Mild Symptoms, Radiographic Findings
Treatment

SOC, TCM
Trial Participants

240

Hebei

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance, Fever, Respiratory Rate
Treatment

SOC, TCM
Trial Participants

110

Hebei

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospitalization, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Treatment-emergent Adverse Events, Respiratory Rate
Treatment

IFN, SOC
Trial Participants

328

Heilongjiang

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Fever, Urine Sample, Blood Pressure, ECG, Radiographic Findings, Renal Outcome (Unspecified)
Treatment

Other, SOC
Trial Participants

240

Heilongjiang

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

30

Heilongjiang

COVID-19 status

Confirmed
Outcome

Mortality, Viral Load or Clearance, Cough, Fever, SpO2, Respiratory Rate, 6-Minute Walking Distance, Radiographic Findings, Quality of Life, Depression, Anxiety
Treatment

Respiratory support, SOC
Trial Participants

60

Heilongjiang

COVID-19 status

Confirmed
Outcome

Mortality, Viral Load or Clearance, Fever, Radiographic Findings, Lung Inflamation
Treatment

Other, SOC
Trial Participants

240

Heilongjiang

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Hospital Discharge, C-Reactive Protein, White Blood Cell Count, Coagulation Test, IgG, IgM or IgA, Antibodies
Treatment

Other, SOC
Trial Participants

350

Helsinki

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Organ Failure or Dysfunction (SOFA)
Treatment

SOC, TCZ
Trial Participants

90

Helsinki

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO, Adverse Events
Treatment

HCQ, Remdesivir, SOC
Trial Participants

NA

Henan

COVID-19 status

Confirmed
Outcome

Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Pneumonia or ARDS, Radiographic Findings, Quality of Life
Treatment

SOC, TCM
Trial Participants

100

Henan

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Treatment-emergent Adverse Events, CD4, CD8, Radiographic Findings
Treatment

Natural Killer Cells, SOC
Trial Participants

30

Henan

COVID-19 status

Resolved
Outcome

Anxiety
Treatment

SOC, TCM
Trial Participants

28

Henan

COVID-19 status

Confirmed
Outcome

Pneumonia or ARDS, Cough, Fever, Dyspnea, Other Mild Symptoms, Radiographic Findings
Treatment

TCM
Trial Participants

24

Henan

COVID-19 status

Confirmed
Outcome

C-Reactive Protein, IL-1, IL-2, IL-4, IL-6, IL-7, IL-8, IL-10, Tumor Necrosis Factor (Any), Granulocyte Stimulaiting Factor, IP-10, White Blood Cell Count, Monocyte Count, Natural Killer Cell Count, Procalcitonin, ALT, Albumin, Bilirubin, Glucose, Urine Sample, Radiographic Findings, Depression, Anxiety, Distress
Treatment

Stem cells
Trial Participants

20

Henan

COVID-19 status

Confirmed
Outcome

Depression, Anxiety
Treatment

Psychological therapy
Trial Participants

81

Henan

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Fever, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events
Treatment

Plasma based therapy, SOC
Trial Participants

30

Henan

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Cough, Fever, Dyspnea, Other Mild Symptoms, CD4, CD8
Treatment

DAA
Trial Participants

10

Henan

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Cough, Fever, Other Mild Symptoms, CD4, CD8
Treatment

DAA
Trial Participants

30

Henan

COVID-19 status

Healthy
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

288

Henan

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Cough, Fever, Other Mild Symptoms, CD4, Radiographic Findings
Treatment

Antivirals, SOC
Trial Participants

20

Henan

COVID-19 status

Resolved
Outcome

Visits or Returns to Emergency Department, Pneumonia or ARDS, Radiographic Findings, Quality of Life
Treatment

SOC, TCM
Trial Participants

100

Henan

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Pneumonia or ARDS, Fever
Treatment

SOC, TCM
Trial Participants

60

Hertfordshire

COVID-19 status

Healthy
Outcome

Viral Load or Clearance, Pneumonia or ARDS
Treatment

HCQ, SOC
Trial Participants

40000

Hessen

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Non-invasive Ventilation, Deep Vein Thrombosis or Pulmonary Embolism, Coagulation Test
Treatment

Anticoagulants, SOC
Trial Participants

400

Ho Chi Minh City

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Pneumonia or ARDS, Fever, Adverse Events
Treatment

HCQ, SOC
Trial Participants

250

Hong Kong

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Adverse Events, IL-6, Tumor Necrosis Factor (Any)
Treatment

LPV/r, LPV/r + IFN
Trial Participants

127

Hong Kong

COVID-19 status

Confirmed
Outcome

Mortality, Viral Load or Clearance, Adverse Events
Treatment

Antibiotics, IFN + Antibiotics, SOC
Trial Participants

81

Hong Kong

COVID-19 status

NA
Outcome

Hospitalization, Viral Load or Clearance, Treatment-emergent Adverse Events, IL-1, IL-2, IL-6, Tumor Necrosis Factor (Any)
Treatment

mAb, SOC
Trial Participants

15

Hong Kong

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Viral Load or Clearance, Adverse Events
Treatment

HCQ, IFN
Trial Participants

60

Hong Kong

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Hong Kong

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Hubei

COVID-19 status

NA
Outcome

Viral Load or Clearance, C-Reactive Protein, Radiographic Findings
Treatment

TCM
Trial Participants

300

Hubei

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, CD4, CD8
Treatment

HCQ, SOC
Trial Participants

300

Hubei

COVID-19 status

Confirmed
Outcome

Hospitalization, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, CD4, PaO2-FiO2, Radiographic Findings
Treatment

SOC, Stem cells
Trial Participants

100

Hubei

COVID-19 status

Healthy
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Fever
Treatment

Education + Monitoring + TCM, Psychological therapy
Trial Participants

600

Hubei

COVID-19 status

Confirmed Or Suspected
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Fever
Treatment

Education, Education + TCM
Trial Participants

400

Hubei

COVID-19 status

Confirmed
Outcome

ICU Admission, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Blood Pressure, Heart Rate, Surfactant Factor Protein, PaO2-FiO2, Respiratory Rate, Radiographic Findings
Treatment

IFN, TCM
Trial Participants

238

Hubei

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Radiographic Findings
Treatment

Corticosteroids, SOC
Trial Participants

100

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Radiographic Findings
Treatment

DRV/c + Other, LPV/r + Other, Other
Trial Participants

100

Hubei

COVID-19 status

Suspected Or Healthy
Outcome

Viral Load or Clearance, Fever, Weight, Height or BMI, Creatinine Phosphokinase, CK-MB, eGFR, ALT, Albumin, Bilirubin, Blood Pressure, Heart Rate, Radiographic Findings
Treatment

SOC, TCM
Trial Participants

160

Hubei

COVID-19 status

Resolved
Outcome

Adverse Events, 6-Minute Walking Distance, Quality of Life
Treatment

SOC, TCM
Trial Participants

100

Hubei

COVID-19 status

Resolved
Outcome

Adverse Events, Serious Adverse Events, PaO2-FiO2, Respiratory Rate, 6-Minute Walking Distance, Quality of Life
Treatment

Psychological therapy, SOC
Trial Participants

100

Hubei

COVID-19 status

Resolved
Outcome

Adverse Events, 6-Minute Walking Distance, Quality of Life
Treatment

Exercise, SOC
Trial Participants

100

Hubei

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Cough, Fever, Adverse Events, 6-Minute Walking Distance, Quality of Life
Treatment

SOC, TCM
Trial Participants

100

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Organ Failure or Dysfunction (SOFA), Treatment-emergent Adverse Events, C-Reactive Protein, Procalcitonin, CD4, CD8, PaO2-FiO2
Treatment

SOC, Stem cells
Trial Participants

48

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

FPV, FPV + TCZ, TCZ
Trial Participants

150

Hubei

COVID-19 status

NA
Outcome

Mortality, Viral Load or Clearance, Cough, Fever, Dyspnea, C-Reactive Protein, IL-1, IL-6, IL-8, Tumor Necrosis Factor (Any), Procalcitonin, CD4, CD8, SpO2, Radiographic Findings
Treatment

NA
Trial Participants

30

Hubei

COVID-19 status

Confirmed
Outcome

Radiographic Findings
Treatment

NA
Trial Participants

36

Hubei

COVID-19 status

Healthy
Outcome

Viral Load or Clearance, Cough, Fever, Dyspnea, Other Mild Symptoms, Adverse Events, Treatment-emergent Adverse Events
Treatment

IFN, IFN + Other
Trial Participants

2944

Hubei

COVID-19 status

Resolved
Outcome

Antibodies, 6-Minute Walking Distance, Radiographic Findings, Renal Outcome (Unspecified)
Treatment

Other, SOC
Trial Participants

60

Hubei

COVID-19 status

Confirmed
Outcome

NA
Treatment

Alternative therapy, SOC
Trial Participants

42

Hubei

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Fever, C-Reactive Protein, Ferritin, IL-6, Tumor Necrosis Factor (Any), White Blood Cell Count, Neutrophils, Creatinine Phosphokinase, CK-MB, Troponin, Procalcitonin, ALT, LDH, CD4, CD8, Respiratory Rate, Radiographic Findings
Treatment

SOC, Stem cells
Trial Participants

20

Hubei

COVID-19 status

Confirmed
Outcome

Pneumonia or ARDS, Radiographic Findings, Quality of Life, Depression, Anxiety, Distress
Treatment

Stem cells
Trial Participants

20

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Organ Failure or Dysfunction (SOFA), Serious Adverse Events
Treatment

FPV, Umifenovir
Trial Participants

240

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, Dyspnea, C-Reactive Protein, PaO2-FiO2, SpO2, Radiographic Findings
Treatment

mAb
Trial Participants

27

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Clinical Improvement Score (Any), Cough, Fever, Other Mild Symptoms
Treatment

Plasma based therapy, SOC
Trial Participants

60

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, PaO2-FiO2
Treatment

Alternative therapy, SOC
Trial Participants

60

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Other Mild Symptoms, Organ Failure or Dysfunction (SOFA), Adverse Events, C-Reactive Protein, CK-MB, ALT, PaO2-FiO2, Radiographic Findings
Treatment

Other
Trial Participants

10

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Pneumonia or ARDS, C-Reactive Protein, Tumor Necrosis Factor (Any), Interferon (Any), Creatinine Phosphokinase, CK-MB, eGFR, ALT, Albumin, Bilirubin, Radiographic Findings
Treatment

SOC, TCM
Trial Participants

300

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO, Hypoxia
Treatment

Non-invasive respiratory support
Trial Participants

60

Hubei

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Creatinine Phosphokinase, CK-MB, ALT, Blood Urea Nitrogen
Treatment

SOC, TCM
Trial Participants

100

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO
Treatment

NA
Trial Participants

96

Hubei

COVID-19 status

Healthy
Outcome

Treatment-emergent Adverse Events, Serious Adverse Events, Antibodies
Treatment

Vaccine
Trial Participants

108

Hubei

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Pneumonia or ARDS, White Blood Cell Count, Monocyte Count, Natural Killer Cell Count, Creatinine Phosphokinase, CK-MB, eGFR, ALT, Albumin, Bilirubin, Glucose, Radiographic Findings
Treatment

TCM
Trial Participants

50

Hubei

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospitalization, Pneumonia or ARDS, Cough, Fever, Dyspnea, Other Mild Symptoms, Radiographic Findings
Treatment

SOC, TCM
Trial Participants

300

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Anti SARS-COV-2 Titers, PaO2-FiO2, Respiratory Rate, Radiographic Findings
Treatment

Igs, SOC
Trial Participants

10

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Other Mild Symptoms, C-Reactive Protein, Tumor Necrosis Factor (Any), Granulocyte Stimulaiting Factor, Erythrocyte Sedimentation Rate, Creatinine Phosphokinase, CK-MB, eGFR, Procalcitonin, ALT, Albumin, Bilirubin
Treatment

LPV/r, SOC
Trial Participants

60

Hubei

COVID-19 status

Confirmed
Outcome

Other Mild Symptoms, Stool Sample
Treatment

SOC, TCM
Trial Participants

200

Hubei

COVID-19 status

NA
Outcome

Viral Load or Clearance, Adverse Events, Serious Adverse Events, Anti SARS-COV-2 Titers, Interferon (Any), IgG, IgM or IgA, Antibodies
Treatment

SOC, Vaccine
Trial Participants

508

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Treatment-emergent Adverse Events, C-Reactive Protein, IL-6, IL-8, Tumor Necrosis Factor (Any), White Blood Cell Count, Shock
Treatment

SOC, TCM
Trial Participants

60

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Dyspnea, Serious Adverse Events, Granulocyte Stimulaiting Factor, White Blood Cell Count, Monocyte Count, Natural Killer Cell Count, Neutrophils, ALT, Albumin, Bilirubin, IgG, IgM or IgA
Treatment

Cyclosporine, HCQ, SOC
Trial Participants

80

Hubei

COVID-19 status

Resolved
Outcome

Clinical Improvement Score (Any), Fever, Antibodies, Radiographic Findings
Treatment

SOC, TCM
Trial Participants

120

Hubei

COVID-19 status

Confirmed
Outcome

ICU Admission, Viral Load or Clearance, Cough, Fever, Other Mild Symptoms
Treatment

SOC, TCM
Trial Participants

400

Hubei

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Pneumonia or ARDS, Cough, Fever, Respiratory Rate
Treatment

Anticoagulants, SOC
Trial Participants

60

Hubei

COVID-19 status

Confirmed
Outcome

NA
Treatment

SOC, TCM
Trial Participants

200

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events
Treatment

LPV/r, SOC
Trial Participants

160

Hubei

COVID-19 status

Confirmed
Outcome

Adverse Events
Treatment

SOC, Stem cells
Trial Participants

70

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, Erythrocyte Sedimentation Rate, Radiographic Findings
Treatment

Other, SOC
Trial Participants

152

Hubei

COVID-19 status

Confirmed
Outcome

NA
Treatment

Corticosteroids, SOC
Trial Participants

86

Hubei

COVID-19 status

Confirmed Or Suspected
Outcome

Viral Load or Clearance
Treatment

TCM
Trial Participants

100

Hubei

COVID-19 status

Confirmed
Outcome

Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Dyspnea, Serious Adverse Events, C-Reactive Protein, PaO2-FiO2, Radiographic Findings
Treatment

SOC, Stem cells
Trial Participants

90

Hubei

COVID-19 status

Confirmed
Outcome

Treatment-emergent Adverse Events
Treatment

IFN, SOC
Trial Participants

328

Hubei

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, White Blood Cell Count, Lymphocyte Count, Neutrophils, Antibodies, Radiographic Findings
Treatment

TCM
Trial Participants

60

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Organ Failure or Dysfunction (SOFA), Treatment-emergent Adverse Events, Radiographic Findings, Renal Outcome (Unspecified)
Treatment

Corticosteroids, SOC
Trial Participants

200

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Pneumonia or ARDS, IL-2, IL-4, IL-6, IL-7, IL-8, IL-10, Tumor Necrosis Factor (Any), White Blood Cell Count, Procalcitonin, PaO2-FiO2, Radiographic Findings
Treatment

Stem cells
Trial Participants

16

Hubei

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any)
Treatment

SOC, TCM
Trial Participants

120

Hubei

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Fever, Dyspnea, SpO2, Radiographic Findings
Treatment

Other, SOC
Trial Participants

340

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, Viral Load or Clearance, Cough, Dyspnea, IL-8
Treatment

Other, SOC
Trial Participants

292

Hubei

COVID-19 status

Confirmed
Outcome

Cough, Fever, Dyspnea
Treatment

TCM
Trial Participants

40

Hubei

COVID-19 status

Confirmed
Outcome

Cough, Fever, Dyspnea
Treatment

SOC, TCM
Trial Participants

40

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, PaO2-FiO2, Radiographic Findings
Treatment

Other, SOC
Trial Participants

294

Hubei

COVID-19 status

Confirmed
Outcome

Adverse Events, Serious Adverse Events, IL-1, IL-6, Tumor Necrosis Factor (Any), Interferon (Any)
Treatment

TCZ
Trial Participants

60

Hubei

COVID-19 status

NA
Outcome

6-Minute Walking Distance, Radiographic Findings, Quality of Life
Treatment

Education, TCM + Education
Trial Participants

160

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation
Treatment

NA
Trial Participants

4

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance, C-Reactive Protein, Natural Killer Cell Count, CD4, CD8
Treatment

IFN, SOC
Trial Participants

80

Hubei

COVID-19 status

Healthy
Outcome

Viral Load or Clearance, Cough, Fever, Serious Adverse Events, C-Reactive Protein, Radiographic Findings
Treatment

HCQ, Umifenovir
Trial Participants

320

Hubei

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Fever, C-Reactive Protein, Radiographic Findings
Treatment

DMARD, SOC
Trial Participants

200

Hubei

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance
Treatment

NA
Trial Participants

40

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Clinical Improvement Score (Any), Cough, Fever, Dyspnea, Other Mild Symptoms
Treatment

Plasma based therapy, SOC
Trial Participants

100

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, Viral Load or Clearance, Fever, Radiographic Findings, Lung Inflamation
Treatment

Other, SOC
Trial Participants

60

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events
Treatment

HCQ, SOC
Trial Participants

80

Hubei

COVID-19 status

Confirmed
Outcome

NA
Treatment

SOC, TCM
Trial Participants

200

Hubei

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Dyspnea, Other Mild Symptoms, Adverse Events, Serious Adverse Events
Treatment

SOC, TCM
Trial Participants

160

Hubei

COVID-19 status

Confirmed
Outcome

Fever
Treatment

SOC, TCM
Trial Participants

160

Hubei

COVID-19 status

Confirmed
Outcome

ICU Admission, Viral Load or Clearance, Pneumonia or ARDS, Cough, Fever, Other Mild Symptoms, Radiographic Findings
Treatment

SOC, TCM
Trial Participants

300

Hubei

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance
Treatment

Other, SOC
Trial Participants

40

Hubei

COVID-19 status

Confirmed Or Suspected
Outcome

Viral Load or Clearance, Radiographic Findings
Treatment

SOC, TCM
Trial Participants

90

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO
Treatment

FPV, SOC
Trial Participants

210

Hubei

COVID-19 status

Confirmed
Outcome

NA
Treatment

Alternative therapy, SOC
Trial Participants

750

Hubei

COVID-19 status

NA
Outcome

Other Mild Symptoms
Treatment

SOC, TCM
Trial Participants

200

Hubei

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any)
Treatment

mAb, Other, SOC
Trial Participants

120

Hubei

COVID-19 status

NA
Outcome

Other Mild Symptoms
Treatment

SOC, TCM
Trial Participants

200

Hubei

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Viral Load or Clearance
Treatment

Other, SOC
Trial Participants

60

Hubei

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Organ Failure or Dysfunction (SOFA), Coagulation Test, Radiographic Findings
Treatment

SOC, TCM
Trial Participants

160

Hubei

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Cough, Fever, Other Mild Symptoms
Treatment

Other
Trial Participants

40

Hubei

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospitalization, Viral Load or Clearance, Non-invasive Ventilation, Cough, Fever, Dyspnea, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, Respiratory Rate
Treatment

LPV/r, SOC
Trial Participants

328

Hubei

COVID-19 status

Resolved
Outcome

Quality of Life, Depression, Anxiety
Treatment

Psychological therapy, TCM, TCM + Psychological therapy
Trial Participants

90

Huila

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, Serious Adverse Events
Treatment

AZT, HCQ, LPV/r, SOC
Trial Participants

1200

Hunan

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Pneumonia or ARDS, PaO2-FiO2, Respiratory Rate
Treatment

Other
Trial Participants

40

Hunan

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Adverse Events
Treatment

LPV/r, LPV/r + Other, Other
Trial Participants

90

Hunan

COVID-19 status

Confirmed
Outcome

PaO2-FiO2, Respiratory Rate, Radiographic Findings
Treatment

Antivirals, TCM + Antiviral
Trial Participants

40

Hunan

COVID-19 status

Healthy
Outcome

Adverse Events, IL-2, IL-4, IL-6, Antibodies
Treatment

SOC, Vaccine
Trial Participants

900

Hunan

COVID-19 status

Healthy
Outcome

Quality of Life
Treatment

TCM
Trial Participants

1000

Hunan

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Radiographic Findings
Treatment

SOC, Stem cells
Trial Participants

60

Hunan

COVID-19 status

Confirmed Or Suspected
Outcome

Viral Load or Clearance, Radiographic Findings
Treatment

Stem cells
Trial Participants

20

Hunan

COVID-19 status

Confirmed Or Suspected
Outcome

NA
Treatment

SOC, TCM
Trial Participants

100

Hunan

COVID-19 status

Suspected
Outcome

Anxiety
Treatment

Psychological therapy, SOC
Trial Participants

51

Idaho

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Adverse Events
Treatment

Razuprotafib, SOC
Trial Participants

180

Idaho

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Fever, Adverse Events, Antibodies, SpO2
Treatment

Other, SOC
Trial Participants

2000

Idaho

COVID-19 status

Confirmed
Outcome

Fever, Serious Adverse Events, Platelet Count, ALT, AST, Albumin, Bilirubin, Blood Pressure, Heart Rate, SpO2
Treatment

Other, SOC
Trial Participants

300

Idaho

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Cardiac Outcome (Unspecified)
Treatment

HCQ, SOC
Trial Participants

120

Idaho

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

40051

Idaho

COVID-19 status

Confirmed
Outcome

Adverse Events
Treatment

Other, SOC
Trial Participants

174

Illinois

COVID-19 status

Confirmed
Outcome

Hospitalization, Fever, Other Mild Symptoms, Adverse Events
Treatment

HCQ
Trial Participants

20

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Treatment-emergent Adverse Events, Weight, Height or BMI
Treatment

Remdesivir, SOC
Trial Participants

1230

Illinois

COVID-19 status

Confirmed
Outcome

Adverse Events, Antibodies
Treatment

Monoclonal antibody, SOC
Trial Participants

24

Illinois

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Deep Vein Thrombosis or Pulmonary Embolism, Quality of Life, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

Plasma based therapy, SOC
Trial Participants

1000

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB, SOC
Trial Participants

2104

Illinois

COVID-19 status

Confirmed
Outcome

Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, C-Reactive Protein
Treatment

SOC, TCZ
Trial Participants

332

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Renal Outcome (Unspecified)
Treatment

SOC, Triterpenes
Trial Participants

440

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, Remdesivir + JAKi
Trial Participants

1034

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any)
Treatment

mAb, SOC
Trial Participants

573

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Treatment-emergent Adverse Events, D-Dimer, Antibodies, PaO2-FiO2, SpO2
Treatment

mAb, SOC
Trial Participants

384

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, PaO2-FiO2
Treatment

Acalabrutinib, SOC
Trial Participants

61

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB
Trial Participants

2970

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Illinois

COVID-19 status

Confirmed
Outcome

Hospitalization, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1450

Illinois

COVID-19 status

NA
Outcome

Hospitalization, Clinical Improvement Score (Any), Fever, Other Mild Symptoms, Adverse Events
Treatment

DMARD
Trial Participants

20

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

52

Illinois

COVID-19 status

NA
Outcome

Mortality, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1300

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Illinois

COVID-19 status

Confirmed
Outcome

Hospitalization, Serious Adverse Events
Treatment

Anticoagulants, SOC
Trial Participants

600

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Fever, Ferritin, Lymphocyte Count, D-Dimer, LDH
Treatment

Other, SOC
Trial Participants

30

Illinois

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6
Treatment

TCZ
Trial Participants

32

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Fever, Adverse Events, Antibodies, SpO2
Treatment

Other, SOC
Trial Participants

2000

Illinois

COVID-19 status

Confirmed
Outcome

Fever
Treatment

Antiretroviral + Dexamethasone, Other, Other + Antiretroviral, Other + Dexamethasone
Trial Participants

525

Illinois

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO, Fever, Other Mild Symptoms, Adverse Events, Respiratory Rate
Treatment

Other, SOC
Trial Participants

190

Illinois

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Illinois

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, Bilirubin
Treatment

Remdesivir
Trial Participants

52

Illinois

COVID-19 status

NA
Outcome

Mortality, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, PaO2-FiO2
Treatment

Positioning
Trial Participants

500

Illinois

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Visits or Returns to Emergency Department
Treatment

Anticoagulants, SOC
Trial Participants

4000

Illinois

COVID-19 status

Confirmed Or Suspected
Outcome

Hospitalization
Treatment

mAb, SOC
Trial Participants

376

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, Ferritin, LDH
Treatment

Other, SOC
Trial Participants

230

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, Ferritin, Platelet Count, Hemoglobin, D-Dimer, Troponin, Fibrinogen, INR, ALT, AST, Bilirubin, LDH
Treatment

Remdesivir, Remdesivir + mAb
Trial Participants

200

Illinois

COVID-19 status

Confirmed
Outcome

NA
Treatment

Non-invasive respiratory support, Positioning + Non-invasive respiratory support
Trial Participants

346

Illinois

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, Troponin
Treatment

SOC, SSRIs
Trial Participants

152

Illinois

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

40051

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, White Blood Cell Count, Monocyte Count, Lymphocyte Count, Neutrophils, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, SOC
Trial Participants

1062

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Organ Failure or Dysfunction (SOFA), Renal Outcome (Unspecified)
Treatment

SGLT2, SOC
Trial Participants

900

Illinois

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Hospital Discharge, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea
Treatment

Plasma based therapy, SOC
Trial Participants

500

Illinois

COVID-19 status

NA
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Adverse Events
Treatment

HCQ, HCQ + AZT, SOC
Trial Participants

20

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, C-Reactive Protein, IL-6, White Blood Cell Count, Platelet Count, Hemoglobin, ALT, AST, Bilirubin, Respiratory Rate, Hypoxemia
Treatment

Sarilumab, SOC
Trial Participants

1912

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, Ferritin, Platelet Count, Hemoglobin, D-Dimer, Troponin, Fibrinogen, INR, ALT, AST, Bilirubin
Treatment

Remdesivir, Remdesivir + mAb
Trial Participants

200

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, C-Reactive Protein, Ferritin, Lymphocyte Count, D-Dimer, LDH
Treatment

Plasma based therapy, SOC
Trial Participants

50

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Serious Adverse Events, Antibodies
Treatment

Plasma based therapy, SOC
Trial Participants

1344

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, INR, ALT, AST, Bilirubin
Treatment

Remdesivir, Remdesivir + IFN
Trial Participants

969

Illinois

COVID-19 status

NA
Outcome

ICU Admission, Hospitalization, Clinical Improvement Score (Any), Fever, Dyspnea, Other Mild Symptoms
Treatment

Plasma based therapy, SOC
Trial Participants

600

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, ALT, Bilirubin
Treatment

mAb, SOC
Trial Participants

270

Illinois

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Organ Failure or Dysfunction (SOFA), Adverse Events
Treatment

JAKi, SOC
Trial Participants

500

Illinois

COVID-19 status

Confirmed
Outcome

Hospitalization
Treatment

Plasma based therapy, SOC
Trial Participants

150

Illinois

COVID-19 status

Confirmed
Outcome

D-Dimer
Treatment

Other, SOC
Trial Participants

80

Illinois

COVID-19 status

NA
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO
Treatment

NA
Trial Participants

10

Illinois

COVID-19 status

NA
Outcome

Hospitalization
Treatment

Anticoagulants, Antihypertensive, SOC
Trial Participants

7000

Illinois

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

SOC, Stem cells
Trial Participants

30

Incheon

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Fever, SpO2, Respiratory Rate
Treatment

Other, SOC
Trial Participants

76

Incheon

COVID-19 status

Confirmed
Outcome

Radiographic Findings
Treatment

Monoclonal antibody
Trial Participants

18

Indiana

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, Remdesivir + JAKi
Trial Participants

1034

Indiana

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Treatment-emergent Adverse Events, D-Dimer, Antibodies, PaO2-FiO2, SpO2
Treatment

mAb, SOC
Trial Participants

384

Indiana

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, PaO2-FiO2
Treatment

Acalabrutinib, SOC
Trial Participants

61

Indiana

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB
Trial Participants

2970

Indiana

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Indiana

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Indiana

COVID-19 status

Confirmed Or Suspected
Outcome

Hospitalization
Treatment

mAb, SOC
Trial Participants

376

Indiana

COVID-19 status

Confirmed
Outcome

Mortality, Organ Failure or Dysfunction (SOFA), Serious Adverse Events, Antibodies
Treatment

Remdesivir, Remdesivir + Other
Trial Participants

10000

Indiana

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

40051

Indiana

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Indiana

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Organ Failure or Dysfunction (SOFA), Adverse Events
Treatment

JAKi, SOC
Trial Participants

500

Inner Mongol

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, White Blood Cell Count, Monocyte Count, Natural Killer Cell Count, Neutrophils, Creatinine Phosphokinase, CK-MB, eGFR, ALT, Albumin, Bilirubin, Urine Sample, Radiographic Findings
Treatment

TCM
Trial Participants

60

Iowa

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB, SOC
Trial Participants

2104

Iowa

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB
Trial Participants

2970

Iowa

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

52

Iowa

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, Ferritin, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Troponin, Fibrinogen, INR, ALT, AST, Albumin, Bilirubin, Glucose, LDH, IgG, IgM or IgA, Blood Urea Nitrogen, Blood Pressure, SpO2, Radiographic Findings
Treatment

Plasma based therapy, SOC
Trial Participants

208

Iowa

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Iowa

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

40051

Iowa

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Iowa

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, INR, ALT, AST, Bilirubin
Treatment

Remdesivir, Remdesivir + IFN
Trial Participants

969

Iowa

COVID-19 status

NA
Outcome

ICU Admission, Hospitalization, Clinical Improvement Score (Any), Fever, Dyspnea, Other Mild Symptoms
Treatment

Plasma based therapy, SOC
Trial Participants

600

Iowa

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Serious Adverse Events, Antibodies
Treatment

mAb, SOC
Trial Participants

124

Islamabad

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), C-Reactive Protein, D-Dimer
Treatment

HCQ, HCQ + AZT, SOC
Trial Participants

75

Islamabad

COVID-19 status

Confirmed
Outcome

NA
Treatment

Other, SOC
Trial Participants

30

Islamabad

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO
Treatment

NA
Trial Participants

500

Islamabad

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Other Mild Symptoms, Treatment-emergent Adverse Events
Treatment

HCQ, SOC
Trial Participants

200

Islamabad

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ + AZT, SOC
Trial Participants

4000

Islamabad

COVID-19 status

Healthy
Outcome

NA
Treatment

HCQ, SOC
Trial Participants

40000

Islamabad

COVID-19 status

Confirmed
Outcome

NA
Treatment

Plasma based therapy, Plasma based therapy + TCZ + Remdesivir + Stem cells, SOC
Trial Participants

600

Islamabad

COVID-19 status

Healthy
Outcome

Viral Load or Clearance, Pneumonia or ARDS
Treatment

HCQ, SOC
Trial Participants

40000

Islamabad

COVID-19 status

Confirmed
Outcome

NA
Treatment

Ivermectin, SOC
Trial Participants

100

Islamabad

COVID-19 status

Suspected
Outcome

Mortality
Treatment

ARBs, ARBs + Statins, NSAIDs, NSAIDs + ARBs, NSAIDs + ARBs + Statins, NSAIDs + Statins, Statins
Trial Participants

10000

Istanbul

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Serious Adverse Events, C-Reactive Protein, Ferritin, Lymphocyte Count, PaO2-FiO2
Treatment

Acalabrutinib, SOC
Trial Participants

163

Istanbul

COVID-19 status

NA
Outcome

Clinical Improvement Score (Any)
Treatment

Other, SOC
Trial Participants

200

Istanbul

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Serious Adverse Events, IgG, IgM or IgA, Antibodies
Treatment

SOC, Vaccine
Trial Participants

13000

Istanbul

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any)
Treatment

SOC, Stem cells
Trial Participants

30

Istanbul

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

Antihypertensive, SOC
Trial Participants

20

Istanbul

COVID-19 status

Healthy
Outcome

Mortality
Treatment

Alternative therapy, SOC
Trial Participants

50

Istanbul

COVID-19 status

NA
Outcome

Dyspnea, Other Mild Symptoms, Depression, Anxiety
Treatment

Education, Non-invasive respiratory support
Trial Participants

270

Istanbul

COVID-19 status

Confirmed Or Suspected
Outcome

NA
Treatment

Inhaled solution, SOC
Trial Participants

60

Izmir

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Serious Adverse Events, IgG, IgM or IgA, Antibodies
Treatment

SOC, Vaccine
Trial Participants

13000

Jakarta

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Fever, Dyspnea, Blood Pressure, Heart Rate, SpO2, Respiratory Rate
Treatment

AZT + Oseltamivir, Stem cells + AZT + Oseltamivir
Trial Participants

40

Jakarta

COVID-19 status

Healthy
Outcome

NA
Treatment

HCQ, SOC
Trial Participants

40000

Jakarta

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Fever, C-Reactive Protein, IL-6, Lymphocyte Count, PaO2-FiO2, SpO2
Treatment

Other, SOC
Trial Participants

368

Jakarta

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ, LPV/r, Remdesivir, SOC
Trial Participants

7000

Jakarta

COVID-19 status

Confirmed
Outcome

Adverse Events, C-Reactive Protein, D-Dimer, INR, Radiographic Findings
Treatment

Plasma based therapy
Trial Participants

10

Jakarta

COVID-19 status

Confirmed
Outcome

Hospitalization, Clinical Improvement Score (Any), Treatment-emergent Adverse Events
Treatment

SOC, Stem cells
Trial Participants

9

Jakarta

COVID-19 status

Healthy
Outcome

Viral Load or Clearance, Pneumonia or ARDS
Treatment

HCQ, SOC
Trial Participants

40000

Jakarta

COVID-19 status

Confirmed
Outcome

NA
Treatment

HCQ, LPV/r, LPV/r + IFN, Remdesivir, SOC
Trial Participants

10000

Jakarta

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Fever, Organ Failure or Dysfunction (SOFA), C-Reactive Protein, IL-6, D-Dimer, PaO2-FiO2
Treatment

Plasma based therapy, SOC
Trial Participants

60

Jakarta

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge
Treatment

Immunomodulators, SOC
Trial Participants

256

Jalisco

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Jalisco

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO, Patient Positioning
Treatment

Positioning, SOC
Trial Participants

200

Jalisco

COVID-19 status

Confirmed
Outcome

NA
Treatment

Ivermectin, SOC
Trial Participants

66

Jalisco

COVID-19 status

Confirmed
Outcome

Mortality, Treatment-emergent Adverse Events
Treatment

Other, SOC
Trial Participants

410

Jerusalem

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, Respiratory Rate, Hypoxemia
Treatment

Sarilumab, SOC
Trial Participants

420

Jerusalem

COVID-19 status

Healthy
Outcome

Adverse Events
Treatment

Other
Trial Participants

5

Jerusalem

COVID-19 status

Confirmed
Outcome

Mortality, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, PaO2-FiO2
Treatment

Other, SOC
Trial Participants

40

Jerusalem

COVID-19 status

Confirmed
Outcome

Mortality, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever
Treatment

Other, SOC
Trial Participants

40

Jerusalem

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Serious Adverse Events, Platelet Count, PaO2-FiO2
Treatment

Apoptotic cells
Trial Participants

5

Jerusalem

COVID-19 status

NA
Outcome

Mortality, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Cough, Dyspnea, Other Mild Symptoms, Adverse Events, Anti SARS-COV-2 Titers, C-Reactive Protein, Ferritin, IL-1, IL-2, IL-6, IL-10, Tumor Necrosis Factor (Any), White Blood Cell Count, Erythrocyte Sedimentation Rate, Procalcitonin, IgG, IgM or IgA, Antibodies, PaO2-FiO2
Treatment

Non-invasive respiratory support
Trial Participants

30

Jerusalem

COVID-19 status

Confirmed
Outcome

NA
Treatment

SOC, Stem cells
Trial Participants

140

Jerusalem

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance
Treatment

HCQ, SOC
Trial Participants

5

Jerusalem

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Fever
Treatment

HCQ, SOC
Trial Participants

1300

Jerusalem

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Labor Absenteeism, Fever, SpO2, Respiratory Rate
Treatment

Other, SOC
Trial Participants

230

Jerusalem

COVID-19 status

Confirmed
Outcome

Hospitalization, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1450

Jerusalem

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA)
Treatment

Dexamethasone, SOC
Trial Participants

299

Jerusalem

COVID-19 status

NA
Outcome

Mortality, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1300

Jerusalem

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

300

Jerusalem

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

270

Jerusalem

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

JAKi, SOC
Trial Participants

260

Jerusalem

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ + AZT, HCQ + Other, SOC
Trial Participants

250

Jerusalem

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance
Treatment

Hygiene
Trial Participants

70

Jerusalem

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Quality of Life
Treatment

HCQ, HCQ + AZT
Trial Participants

440

Jerusalem

COVID-19 status

Confirmed
Outcome

Mortality, D-Dimer, Troponin
Treatment

Anticoagulants
Trial Participants

600

Jerusalem

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, Adverse Events
Treatment

IFN, SOC
Trial Participants

40

Jerusalem

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, Ferritin, LDH
Treatment

Other, SOC
Trial Participants

230

Jerusalem

COVID-19 status

Confirmed
Outcome

NA
Treatment

SOC, TCZ
Trial Participants

500

Jerusalem

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Serious Adverse Events, Platelet Count, PaO2-FiO2
Treatment

Cell-based therapeutic
Trial Participants

24

Jerusalem

COVID-19 status

Confirmed
Outcome

NA
Treatment

HCQ, LPV/r, LPV/r + IFN, Remdesivir, SOC
Trial Participants

10000

Jerusalem

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious or Seconday Infections, Serious Adverse Events, ALT
Treatment

Sarilumab, SOC
Trial Participants

460

Jerusalem

COVID-19 status

Confirmed
Outcome

ICU Admission, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Adverse Events, SpO2
Treatment

Other, SOC
Trial Participants

50

Jerusalem

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

300

Jerusalem

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance
Treatment

Ivermectin, SOC
Trial Participants

100

Jiangsu

COVID-19 status

Confirmed
Outcome

Non-invasive Ventilation, White Blood Cell Count, Creatinine Phosphokinase, CK-MB, ALT, PaO2-FiO2, Respiratory Rate
Treatment

SOC, TCM
Trial Participants

50

Jiangsu

COVID-19 status

NA
Outcome

Serious or Seconday Infections, Adverse Events, Anti SARS-COV-2 Titers
Treatment

SOC, Vaccine
Trial Participants

500

Jiangsu

COVID-19 status

Healthy
Outcome

Urine Sample, IgG, IgM or IgA, Antibodies
Treatment

SOC, Vaccine
Trial Participants

144

Jiangsu

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Pneumonia or ARDS, Fever, Dyspnea, Other Mild Symptoms, C-Reactive Protein, White Blood Cell Count, Erythrocyte Sedimentation Rate, Procalcitonin
Treatment

SOC, TCM
Trial Participants

100

Jiangsu

COVID-19 status

Confirmed Or Suspected
Outcome

Viral Load or Clearance, White Blood Cell Count, Radiographic Findings
Treatment

Other, SOC
Trial Participants

26

Jiangsu

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, C-Reactive Protein, IL-6, LDH, Respiratory Rate, Renal Outcome (Unspecified)
Treatment

Plasma based therapy, SOC
Trial Participants

90

Jiangsu

COVID-19 status

Confirmed
Outcome

NA
Treatment

FPV
Trial Participants

9

Jiangsu

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Adverse Events, Weight, Height or BMI, Antibodies, Blood Pressure, ECG
Treatment

mAb, SOC
Trial Participants

456

Jiangxi

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Pneumonia or ARDS
Treatment

LPV/r, LPV/r + TCM
Trial Participants

80

Jiangxi

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Fever, C-Reactive Protein, Erythrocyte Sedimentation Rate, CD4, Respiratory Rate, Radiographic Findings
Treatment

SOC, TCM
Trial Participants

120

Jiangxi

COVID-19 status

Confirmed
Outcome

Mortality, Treatment-emergent Adverse Events
Treatment

SOC, Stem cells + Natural Killer Cells
Trial Participants

20

Jiangxi

COVID-19 status

Resolved
Outcome

Fever, Respiratory Rate, 6-Minute Walking Distance, Quality of Life, Depression, Anxiety, Distress
Treatment

Exercise, Exercise + Respiratory support, Respiratory support
Trial Participants

108

Jiangxi

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Pneumonia or ARDS, Cough, Fever
Treatment

SOC, TCM
Trial Participants

72

Jiangxi

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance
Treatment

Plasma based therapy, SOC
Trial Participants

100

Jiangxi

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO
Treatment

Stem cells
Trial Participants

16

Jiangxi

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Fever, Dyspnea, C-Reactive Protein, ALT, Bilirubin, Antibodies
Treatment

Plasma based therapy
Trial Participants

10

Jiangxi

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Adverse Events, PaO2-FiO2, Respiratory Rate
Treatment

DAA, IFN, TCM
Trial Participants

50

Jilin

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Viral Load or Clearance, Cough, Fever, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events
Treatment

HCQ
Trial Participants

10

Kabul

COVID-19 status

NA
Outcome

NA
Treatment

Plasma based therapy
Trial Participants

NA

Kaluga

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

mAb, SOC
Trial Participants

206

Kampala

COVID-19 status

Healthy
Outcome

NA
Treatment

HCQ, SOC
Trial Participants

30000

Kampala

COVID-19 status

Confirmed
Outcome

Mortality, SpO2
Treatment

HCQ, LPV/r, SOC
Trial Participants

3000

Kanagawa

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Kanagawa

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Kanagawa

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Kanagawa

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Kandahar

COVID-19 status

NA
Outcome

NA
Treatment

Plasma based therapy
Trial Participants

NA

Kansas

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Deep Vein Thrombosis or Pulmonary Embolism, Quality of Life, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

Plasma based therapy, SOC
Trial Participants

1000

Kansas

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Non-invasive Ventilation, Deep Vein Thrombosis or Pulmonary Embolism, Adverse Events, Treatment-emergent Adverse Events, Bicarbonates
Treatment

ARBs
Trial Participants

34

Kansas

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Remdesivir + Costimulation blocker, Remdesivir + mAb, Remdesivir + Other
Trial Participants

2160

Kansas

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Fever, Adverse Events, Antibodies, SpO2
Treatment

Other, SOC
Trial Participants

2000

Kansas

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, Ferritin, LDH
Treatment

Other, SOC
Trial Participants

230

Kansas

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

40051

Kansas

COVID-19 status

NA
Outcome

Adverse Events, IgG, IgM or IgA, Antibodies
Treatment

Vaccine
Trial Participants

260

Kansas

COVID-19 status

Confirmed
Outcome

Mortality, Pneumonia or ARDS, Fever, Serious Adverse Events, IL-1, IL-8, Tumor Necrosis Factor (Any), SpO2, Distress
Treatment

Other, SOC
Trial Participants

36

Kansas

COVID-19 status

Confirmed
Outcome

Hospitalization
Treatment

Other, SOC
Trial Participants

174

Karnataka

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ + AZT, SOC
Trial Participants

4000

Karnataka

COVID-19 status

Confirmed
Outcome

Hospital Discharge
Treatment

Psychological therapy, SOC
Trial Participants

40

Karnataka

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Pneumonia or ARDS, Cough, Fever, Organ Failure or Dysfunction (SOFA), Antibodies, PaO2-FiO2, SpO2, Radiographic Findings, Distress, Renal Outcome (Unspecified)
Treatment

Plasma based therapy, SOC
Trial Participants

24

Kathmandu

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance
Treatment

Alternative therapy, SOC
Trial Participants

100

Kayseri

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Serious Adverse Events, IgG, IgM or IgA, Antibodies
Treatment

SOC, Vaccine
Trial Participants

13000

Kayseri

COVID-19 status

Confirmed
Outcome

NA
Treatment

Other
Trial Participants

60

Kent

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, Ferritin, LDH
Treatment

Other, SOC
Trial Participants

230

Kentucky

COVID-19 status

Confirmed
Outcome

Adverse Events, Antibodies
Treatment

Monoclonal antibody, SOC
Trial Participants

24

Kentucky

COVID-19 status

Healthy
Outcome

Mortality, Serious Adverse Events, Interferon (Any), Antibodies
Treatment

SOC, Vaccine
Trial Participants

6578

Kentucky

COVID-19 status

Healthy
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6
Treatment

Vaccine
Trial Participants

120

Kentucky

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, PaO2-FiO2
Treatment

Acalabrutinib, SOC
Trial Participants

61

Kentucky

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB
Trial Participants

2970

Kentucky

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, PaO2-FiO2, Radiographic Findings, Hypoxia
Treatment

Inhaled solution, SOC
Trial Participants

144

Kentucky

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events, PaO2-FiO2
Treatment

mAb, SOC
Trial Participants

300

Kentucky

COVID-19 status

Healthy
Outcome

Serious Adverse Events, Antibodies
Treatment

SOC, Vaccine
Trial Participants

180

Kentucky

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ, SOC
Trial Participants

479

Kentucky

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Deep Vein Thrombosis or Pulmonary Embolism, Renal Outcome (Unspecified)
Treatment

Other
Trial Participants

366

Kentucky

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, Ferritin, LDH
Treatment

Other, SOC
Trial Participants

230

Kentucky

COVID-19 status

Confirmed
Outcome

Mortality, Organ Failure or Dysfunction (SOFA), Serious Adverse Events, Antibodies
Treatment

Remdesivir, Remdesivir + Other
Trial Participants

10000

Kentucky

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

40051

Kentucky

COVID-19 status

NA
Outcome

Adverse Events, IgG, IgM or IgA, Antibodies
Treatment

Vaccine
Trial Participants

260

Kentucky

COVID-19 status

NA
Outcome

ICU Admission, Hospitalization, Clinical Improvement Score (Any), Fever, Dyspnea, Other Mild Symptoms
Treatment

Plasma based therapy, SOC
Trial Participants

600

Kentucky

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Serious Adverse Events
Treatment

Immunomodulators, SOC
Trial Participants

129

Kentucky

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Distress
Treatment

Igs, SOC
Trial Participants

100

Kentucky

COVID-19 status

Confirmed
Outcome

Mortality, C-Reactive Protein, Ferritin, IL-6, Lymphocyte Count, D-Dimer
Treatment

Plasma based therapy
Trial Participants

100

Kerman

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance
Treatment

Stem cells
Trial Participants

10

Kerman

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Cough, Fever, Dyspnea, Other Mild Symptoms, SpO2, Respiratory Rate
Treatment

Alternative therapy, SOC
Trial Participants

80

Kermanshah

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

Other, SOC
Trial Participants

50

Kermanshah

COVID-19 status

Confirmed
Outcome

Radiographic Findings
Treatment

Ivermectin, SOC
Trial Participants

50

Kermanshah

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), C-Reactive Protein, PaO2-FiO2
Treatment

Other, SOC
Trial Participants

50

Khartoum

COVID-19 status

Confirmed
Outcome

Mortality, Viral Load or Clearance
Treatment

Other
Trial Participants

110

Khartoum

COVID-19 status

Confirmed
Outcome

Mortality, SpO2
Treatment

HCQ, LPV/r, SOC
Trial Participants

3000

Khuzestan

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge
Treatment

HCQ + LPV/r, HCQ + LPV/r + Ivermectin
Trial Participants

60

Khuzestan

COVID-19 status

Confirmed
Outcome

ICU Admission, Cough, Fever, Dyspnea, Other Mild Symptoms
Treatment

DAA, SOC
Trial Participants

1000

Khuzestan

COVID-19 status

NA
Outcome

Cough, Fever, Dyspnea
Treatment

Other, SOC, Vitamins, Vitamins + Other
Trial Participants

100

Khuzestan

COVID-19 status

Confirmed
Outcome

Platelet Count
Treatment

Alternative therapy, SOC
Trial Participants

88

Kigali

COVID-19 status

Confirmed Or Healthy
Outcome

Mortality, Hospital Discharge, Pneumonia or ARDS, Distress
Treatment

HCQ, HCQ + LPV/r, LPV/r, SOC
Trial Participants

6400

Kinshasa

COVID-19 status

Confirmed
Outcome

Mortality, SpO2
Treatment

HCQ, LPV/r, SOC
Trial Participants

3000

Kirov

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Radiographic Findings
Treatment

FPV, SOC
Trial Participants

330

Kocaeli

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Serious Adverse Events, IgG, IgM or IgA, Antibodies
Treatment

SOC, Vaccine
Trial Participants

13000

Konya

COVID-19 status

Confirmed
Outcome

Other Mild Symptoms, Quality of Life, Depression, Anxiety
Treatment

Education, Exercise, Respiratory support
Trial Participants

36

Krasnoyarsk

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, Quality of Life
Treatment

Other, SOC
Trial Participants

140

Kuala Lumpur

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance
Treatment

Hygiene, SOC
Trial Participants

20

Kuala Lumpur

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Non-invasive Ventilation
Treatment

Corticosteroids, TCZ
Trial Participants

310

Kuala Lumpur

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Labor Absenteeism, Fever, SpO2, Respiratory Rate
Treatment

Other, SOC
Trial Participants

230

Kuala Lumpur

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

300

Kuala Lumpur

COVID-19 status

Confirmed
Outcome

NA
Treatment

HCQ, LPV/r, LPV/r + IFN, Remdesivir, SOC
Trial Participants

10000

Kuala Lumpur

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

300

Kuwait City

COVID-19 status

Confirmed
Outcome

ICU Admission, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Adverse Events, Radiographic Findings, Hypoxia
Treatment

FPV, SOC
Trial Participants

780

Kuwait City

COVID-19 status

Confirmed
Outcome

NA
Treatment

Cyclosporin + Steroids
Trial Participants

12

Kuwait City

COVID-19 status

NA
Outcome

NA
Treatment

Plasma based therapy
Trial Participants

NA

Kuwait City

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any)
Treatment

Plasma based therapy, SOC
Trial Participants

300

Kyiv (Kiev)

COVID-19 status

Confirmed
Outcome

C-Reactive Protein
Treatment

Other, SOC
Trial Participants

100

Kyiv (Kiev)

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Pneumonia or ARDS, Cough, Fever, C-Reactive Protein, PaO2-FiO2
Treatment

Antibiotics + AZT + Corticosteroids + Anticoagulants + Other, Stem cells + Antibiotics + AZT + Corticosteroids + Anticoagulants + Other
Trial Participants

30

Kyiv (Kiev)

COVID-19 status

Healthy
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

60000

Kyiv (Kiev)

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO, Fever, Other Mild Symptoms, Adverse Events, Respiratory Rate
Treatment

Other, SOC
Trial Participants

190

Kyiv (Kiev)

COVID-19 status

Confirmed
Outcome

NA
Treatment

Other, SOC
Trial Participants

222

Kyiv (Kiev)

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Fever, Lymphocyte Count
Treatment

Igs, SOC
Trial Participants

76

La Rioja

COVID-19 status

Healthy
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6
Treatment

HCQ, HCQ + NRTIs, NRTIs, SOC
Trial Participants

4000

Lacs

COVID-19 status

Confirmed
Outcome

C-Reactive Protein
Treatment

LPV/r, LPV/r + Immunomodulators, LPV/r + Statins
Trial Participants

294

Lancashire

COVID-19 status

Confirmed
Outcome

Hospitalization, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1450

Las Palmas

COVID-19 status

Healthy
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6
Treatment

HCQ, HCQ + NRTIs, NRTIs, SOC
Trial Participants

4000

Lecco

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, D-Dimer, Troponin
Treatment

Other, SOC
Trial Participants

1034

Leeds

COVID-19 status

Healthy
Outcome

Adverse Events
Treatment

Antivirals, SOC
Trial Participants

130

Leeds

COVID-19 status

Healthy
Outcome

IgG, IgM or IgA
Treatment

SOC, Vitamins
Trial Participants

4400

Leeds

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, Remdesivir + JAKi
Trial Participants

1034

Leeds

COVID-19 status

Healthy
Outcome

Viral Load or Clearance, Pneumonia or ARDS
Treatment

HCQ, SOC
Trial Participants

40000

Leeds

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, White Blood Cell Count, Monocyte Count, Lymphocyte Count, Neutrophils, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, SOC
Trial Participants

1062

Liaoning

COVID-19 status

Confirmed
Outcome

Pneumonia or ARDS, Radiographic Findings
Treatment

Other, SOC
Trial Participants

45

Liaoning

COVID-19 status

Confirmed Or Suspected
Outcome

Depression, Anxiety, Distress
Treatment

TCM
Trial Participants

60

Liaoning

COVID-19 status

Confirmed
Outcome

Depression, Anxiety
Treatment

Rehabilitation
Trial Participants

160

Liaoning

COVID-19 status

Confirmed
Outcome

Viral Load or Clearance, Adverse Events, Serious Adverse Events, PaO2-FiO2, Respiratory Rate
Treatment

DAA, SOC
Trial Participants

20

Liaoning

COVID-19 status

Confirmed Or Suspected
Outcome

Quality of Life
Treatment

TCM, TCM + Psychological therapy
Trial Participants

60

Liege

COVID-19 status

NA
Outcome

Adverse Events, IgG, IgM or IgA, Antibodies
Treatment

Vaccine
Trial Participants

260

Lima

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Serious Adverse Events, C-Reactive Protein, Ferritin, Lymphocyte Count, PaO2-FiO2
Treatment

Acalabrutinib, SOC
Trial Participants

163

Lima

COVID-19 status

Confirmed
Outcome

Mortality, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events
Treatment

Plasma based therapy, SOC
Trial Participants

192

Lima

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any)
Treatment

mAb, SOC
Trial Participants

573

Lima

COVID-19 status

NA
Outcome

Invasive Mechanical Ventilation or ECMO
Treatment

SOC, TCZ
Trial Participants

379

Lima

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Lima

COVID-19 status

Healthy
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

60000

Lima

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ, LPV/r, Remdesivir, SOC
Trial Participants

7000

Lima

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, Quality of Life
Treatment

Other, SOC
Trial Participants

140

Lima

COVID-19 status

NA
Outcome

ICU Admission, Invasive Mechanical Ventilation or ECMO
Treatment

JAKi, SOC
Trial Participants

402

Lima

COVID-19 status

Confirmed
Outcome

NA
Treatment

HCQ, LPV/r, LPV/r + IFN, Remdesivir, SOC
Trial Participants

10000

Lima

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Serious Adverse Events
Treatment

Monoclonal antibody, SOC
Trial Participants

1360

Lima

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

40051

Lima

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, SpO2
Treatment

Other, SOC
Trial Participants

1034

Lima

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, C-Reactive Protein, Ferritin, Lymphocyte Count, SpO2
Treatment

Acalabrutinib, SOC
Trial Participants

177

Limburg

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Viral Load or Clearance, Organ Failure or Dysfunction (SOFA)
Treatment

Broad- spectrum sorbent hemoperfusion device, SOC
Trial Participants

42

Lisbon

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, White Blood Cell Count, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose, Blood Pressure, Heart Rate, SpO2, Pregnancy or Birth Outcomes
Treatment

Other, SOC
Trial Participants

NA

Lisbon

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events, White Blood Cell Count, Platelet Count, Hemoglobin, Prothrombin, Electrolytes, INR, ALT, AST, Bilirubin, Glucose, Renal Outcome (Unspecified)
Treatment

HCQ, LPV/r, Remdesivir
Trial Participants

3100

Liverpool

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Liverpool

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, Bilirubin
Treatment

Remdesivir
Trial Participants

52

Liverpool

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Liverpool

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

London

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, SpO2
Treatment

Other, SOC
Trial Participants

1034

London

COVID-19 status

Confirmed
Outcome

Mortality, Non-invasive Ventilation
Treatment

Other, SOC
Trial Participants

NA

London

COVID-19 status

Confirmed Or Suspected
Outcome

Hospitalization, Clinical Improvement Score (Any), Other Mild Symptoms, Adverse Events
Treatment

Hygiene, SOC
Trial Participants

405

London

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, Renal Outcome (Unspecified)
Treatment

NA
Trial Participants

20000

London

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Pneumonia or ARDS
Treatment

AZT, SOC
Trial Participants

800

London

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

London

COVID-19 status

Confirmed Or Suspected
Outcome

IL-1, IL-6
Treatment

Anakinra, SOC
Trial Participants

40

London

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Viral Load or Clearance, Adverse Events, Blood Pressure, Heart Rate, ECG, SpO2, Respiratory Rate, Renal Outcome (Unspecified)
Treatment

Anticoagulants, Other, SOC
Trial Participants

NA

London

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Deep Vein Thrombosis or Pulmonary Embolism, von Wildebrandt Factor, Troponin, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

Plasma based therapy, SOC
Trial Participants

NA

London

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Pneumonia or ARDS, Cough, Fever, Dyspnea, Other Mild Symptoms, Blood Pressure, Heart Rate, SpO2, Respiratory Rate
Treatment

IFN, SOC
Trial Participants

400

London

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Blood Gas, PaO2-FiO2, Respiratory Rate, Blood pH
Treatment

Other, SOC
Trial Participants

85

London

COVID-19 status

NA
Outcome

Adverse Events, Serious Adverse Events, PaO2-FiO2
Treatment

Other, SOC
Trial Participants

24

London

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Other Mild Symptoms, Serious or Seconday Infections, Adverse Events, Anti SARS-COV-2 Titers
Treatment

Vaccine
Trial Participants

1112

London

COVID-19 status

Confirmed
Outcome

Mortality, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Renal Outcome (Unspecified)
Treatment

Immunomodulators, JAKi, SOC
Trial Participants

456

London

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Hospital Discharge, Viral Load or Clearance, Fever, Adverse Events, Bilirubin, Stool Sample
Treatment

FPV, LPV/r, LPV/r + FPV, SOC
Trial Participants

240

London

COVID-19 status

Healthy
Outcome

NA
Treatment

HCQ, SOC
Trial Participants

30000

London

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, D-Dimer, Troponin
Treatment

Other, SOC
Trial Participants

1034

London

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), SpO2
Treatment

mAb, SOC
Trial Participants

270

London

COVID-19 status

Confirmed
Outcome

Adverse Events
Treatment

Radiation therapy
Trial Participants

13

London

COVID-19 status

Confirmed Or Suspected
Outcome

Viral Load or Clearance
Treatment

FPV, LPV/r, LPV/r + FPV, SOC
Trial Participants

240

London

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, IL-6, Tumor Necrosis Factor (Any), D-Dimer, Angiotensins, ACE, ECG, SpO2
Treatment

Other, SOC
Trial Participants

465

London

COVID-19 status

Suspected
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ, SOC
Trial Participants

3000

London

COVID-19 status

Suspected
Outcome

Mortality, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Adverse Events
Treatment

AZT, SOC
Trial Participants

800

London

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, Remdesivir + JAKi
Trial Participants

1034

London

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Labor Absenteeism, Fever, SpO2, Respiratory Rate
Treatment

Other, SOC
Trial Participants

230

London

COVID-19 status

Healthy
Outcome

Stool Sample, CD4
Treatment

SOC, Vaccine
Trial Participants

12390

London

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Labor Absenteeism, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Hyper-Inflammation, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Deep Vein Thrombosis or Pulmonary Embolism, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6, Tumor Necrosis Factor (Any), White Blood Cell Count, D-Dimer, Creatinine Phosphokinase, Bilirubin, Glucose, Antibodies, PaO2-FiO2, Radiographic Findings, Lung Inflamation, Hypoxemia, Quality of Life
Treatment

SOC, TCZ
Trial Participants

450

London

COVID-19 status

Confirmed
Outcome

Treatment-emergent Adverse Events
Treatment

Remdesivir
Trial Participants

2500

London

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Other Mild Symptoms, Adverse Events
Treatment

HCQ, SOC
Trial Participants

NA

London

COVID-19 status

Suspected
Outcome

Viral Load or Clearance
Treatment

Alternative therapy, SOC
Trial Participants

120

London

COVID-19 status

Healthy
Outcome

NA
Treatment

Hygien, SOC
Trial Participants

300

London

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Serious Adverse Events, Fibrinogen, PaO2-FiO2
Treatment

Anticoagulants, SOC
Trial Participants

36

London

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

300

London

COVID-19 status

Confirmed
Outcome

C-Reactive Protein
Treatment

Other, SOC
Trial Participants

100

London

COVID-19 status

Confirmed
Outcome

NA
Treatment

Non-invasive respiratory support, SOC
Trial Participants

300

London

COVID-19 status

Confirmed Or Healthy
Outcome

Mortality, Hospital Discharge, Pneumonia or ARDS, Distress
Treatment

HCQ, HCQ + LPV/r, LPV/r, SOC
Trial Participants

6400

London

COVID-19 status

Confirmed Or Suspected
Outcome

ICU Admission, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, SpO2, Respiratory Rate
Treatment

FPV, HCQ + AZT + Zinc, SOC
Trial Participants

450

London

COVID-19 status

Healthy
Outcome

NA
Treatment

HCQ, SOC
Trial Participants

40000

London

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Serious or Seconday Infections, C-Reactive Protein, Ferritin, Lymphocyte Count, D-Dimer, CD4, CD8
Treatment

Other, SOC
Trial Participants

48

London

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

150

London

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events
Treatment

Remdesivir
Trial Participants

52

London

COVID-19 status

NA
Outcome

Hospitalization, Viral Load or Clearance, Other Mild Symptoms
Treatment

HCQ, SOC
Trial Participants

1000

London

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Renal Outcome (Unspecified)
Treatment

JAKi, mAb, SOC
Trial Participants

375

London

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, PaO2-FiO2
Treatment

Inhaled solution, SOC
Trial Participants

50

London

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

London

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Adverse Events, Blood Pressure, Heart Rate, Respiratory Rate, Quality of Life
Treatment

Other, SOC
Trial Participants

1800

London

COVID-19 status

NA
Outcome

Mortality, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, Fibrinogen, PaO2-FiO2
Treatment

Other, SOC
Trial Participants

24

London

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

FPV, HCQ + AZT + Zinc, SOC
Trial Participants

450

London

COVID-19 status

Confirmed
Outcome

NA
Treatment

Other, SOC
Trial Participants

222

London

COVID-19 status

Confirmed Or Suspected
Outcome

Viral Load or Clearance
Treatment

Hygiene, SOC
Trial Participants

40

London

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, LDH
Treatment

Antihypertensive, SOC
Trial Participants

200

London

COVID-19 status

Confirmed
Outcome

NA
Treatment

Antihypertensive, SOC
Trial Participants

60

London

COVID-19 status

Confirmed
Outcome

NA
Treatment

DPP1 inhibitor, SOC
Trial Participants

300

London

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Clinical Improvement Score (Any), Serious Adverse Events
Treatment

Other, SOC
Trial Participants

150

London

COVID-19 status

Confirmed
Outcome

Adverse Events, C-Reactive Protein, Ferritin, D-Dimer, Troponin, Prothrombin, Fibrinogen, Coagulation Test, Triglycerides, Electrolytes, INR, ALT, AST, Albumin, Bilirubin, Glucose, LDH, Blood Pressure, Heart Rate, ECG, Respiratory Rate, Bicarbonates
Treatment

Anticoagulants, Other, SOC
Trial Participants

100

London

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any)
Treatment

IFN, SOC
Trial Participants

220

London

COVID-19 status

NA
Outcome

NA
Treatment

SOC, SOC + Vaccine, Vaccine, Vaccine + Vaccine
Trial Participants

9000

London

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, Bilirubin
Treatment

Remdesivir
Trial Participants

52

London

COVID-19 status

Confirmed
Outcome

ICU Admission, Pneumonia or ARDS, Organ Failure or Dysfunction (SOFA), C-Reactive Protein, D-Dimer, Procalcitonin
Treatment

Inhaled solution, SOC
Trial Participants

40

London

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, Ferritin, D-Dimer, Radiographic Findings
Treatment

JAKi
Trial Participants

NA

London

COVID-19 status

Healthy
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

1090

London

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Fever, Serious or Seconday Infections, Adverse Events, C-Reactive Protein, Ferritin, Lymphocyte Count, Neutrophils, D-Dimer, Triglycerides, LDH, PaO2-FiO2, SpO2, Respiratory Rate
Treatment

mAb, Other
Trial Participants

NA

London

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, SpO2
Treatment

JAKi, SOC
Trial Participants

402

London

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Non-invasive Ventilation
Treatment

Other, SOC
Trial Participants

389

London

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, Ferritin, LDH
Treatment

Other, SOC
Trial Participants

230

London

COVID-19 status

Healthy
Outcome

Serious Adverse Events
Treatment

Vaccine
Trial Participants

12330

London

COVID-19 status

Resolved
Outcome

Adverse Events
Treatment

Psychological therapy, SOC
Trial Participants

26

London

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Adverse Events, Renal Outcome (Unspecified)
Treatment

JAKi, mAb, SOC
Trial Participants

NA

London

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, PaO2-FiO2, SpO2
Treatment

NSAIDs, SOC
Trial Participants

NA

London

COVID-19 status

Confirmed
Outcome

Hospitalization, Non-invasive Ventilation
Treatment

Remdesivir, SOC
Trial Participants

400

London

COVID-19 status

Healthy
Outcome

Adverse Events
Treatment

mAb, SOC
Trial Participants

60

London

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, PaO2-FiO2
Treatment

NSAIDs, SOC
Trial Participants

230

London

COVID-19 status

Confirmed
Outcome

Fever, Other Mild Symptoms, Serious Adverse Events, IgG, IgM or IgA, Antibodies
Treatment

Vaccine
Trial Participants

320

London

COVID-19 status

Healthy
Outcome

NA
Treatment

HCQ, SOC
Trial Participants

500

London

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

London

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

SGLT2, SOC
Trial Participants

900

London

COVID-19 status

Confirmed
Outcome

NA
Treatment

Hygiene
Trial Participants

22

London

COVID-19 status

Healthy
Outcome

Viral Load or Clearance, Pneumonia or ARDS
Treatment

HCQ, SOC
Trial Participants

40000

London

COVID-19 status

NA
Outcome

ICU Admission, Invasive Mechanical Ventilation or ECMO
Treatment

JAKi, SOC
Trial Participants

402

London

COVID-19 status

Healthy
Outcome

NA
Treatment

HCQ, SOC
Trial Participants

40000

London

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Adverse Events, Platelet Count, Hemoglobin, ALT, SpO2, Radiographic Findings
Treatment

Other, SOC
Trial Participants

250

London

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Platelet Count, Hemoglobin, ALT, AST, Bilirubin, Glucose, Surfactant Factor Protein, PaO2-FiO2
Treatment

Other, SOC
Trial Participants

20

London

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Renal Outcome (Unspecified)
Treatment

Oseltamivir, Oseltamivir + Other
Trial Participants

120

London

COVID-19 status

Confirmed
Outcome

NA
Treatment

Other
Trial Participants

2000

London

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Lymphocyte Count
Treatment

Other, SOC
Trial Participants

48

London

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Platelet Count, Hemoglobin, ALT, AST, Bilirubin
Treatment

DPP1 inhibitor, SOC
Trial Participants

300

London

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, White Blood Cell Count, Monocyte Count, Lymphocyte Count, Neutrophils, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, SOC
Trial Participants

1062

London

COVID-19 status

Confirmed
Outcome

NA
Treatment

FPV, SOC
Trial Participants

302

London

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Labor Absenteeism, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Adverse Events
Treatment

Vaccine
Trial Participants

10078

London

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, SpO2
Treatment

Other, SOC
Trial Participants

300

London

COVID-19 status

Confirmed
Outcome

Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Adverse Events, C-Reactive Protein, Ferritin, IL-6, IL-10, Tumor Necrosis Factor (Any)
Treatment

Other, SOC
Trial Participants

106

London

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Serious Adverse Events, SpO2
Treatment

Other, SOC
Trial Participants

90

London

COVID-19 status

Suspected
Outcome

Visits or Returns to Emergency Department, Viral Load or Clearance, Fever, SpO2
Treatment

Corticosteroids, SOC
Trial Participants

478

London

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

300

London

COVID-19 status

Confirmed Or Suspected
Outcome

Clinical Improvement Score (Any)
Treatment

IFN, SOC
Trial Participants

820

London

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, Ferritin, Lymphocyte Count, D-Dimer, LDH, SpO2, Renal Outcome (Unspecified)
Treatment

Other, Other + SGLT2, SOC
Trial Participants

1407

London

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Louisiana

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Deep Vein Thrombosis or Pulmonary Embolism, Quality of Life, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

Plasma based therapy, SOC
Trial Participants

1000

Louisiana

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB, SOC
Trial Participants

2104

Louisiana

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Non-invasive Ventilation
Treatment

NA
Trial Participants

48

Louisiana

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6
Treatment

Non-invasive respiratory support, SOC
Trial Participants

70

Louisiana

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, Remdesivir + JAKi
Trial Participants

1034

Louisiana

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any)
Treatment

mAb, SOC
Trial Participants

573

Louisiana

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Treatment-emergent Adverse Events, D-Dimer, Antibodies, PaO2-FiO2, SpO2
Treatment

mAb, SOC
Trial Participants

384

Louisiana

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Weight, Height or BMI, Antibodies
Treatment

mAB
Trial Participants

2970

Louisiana

COVID-19 status

Confirmed
Outcome

NA
Treatment

Immunomodulators, SOC
Trial Participants

38

Louisiana

COVID-19 status

Healthy
Outcome

NA
Treatment

HCQ, Vitamins
Trial Participants

829

Louisiana

COVID-19 status

Confirmed
Outcome

NA
Treatment

Non-invasive respiratory support, SOC
Trial Participants

200

Louisiana

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Invasive Mechanical Ventilation or ECMO
Treatment

SOC, Trpc6 inhibitor
Trial Participants

90

Louisiana

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, Ferritin, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Troponin, Fibrinogen, INR, ALT, AST, Albumin, Bilirubin, Glucose, LDH, IgG, IgM or IgA, Blood Urea Nitrogen, Blood Pressure, SpO2, Radiographic Findings
Treatment

Plasma based therapy, SOC
Trial Participants

208

Louisiana

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Fever, Adverse Events, Antibodies, SpO2
Treatment

Other, SOC
Trial Participants

2000

Louisiana

COVID-19 status

Healthy
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

60

Louisiana

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality
Treatment

SOC, Vaccine
Trial Participants

96

Louisiana

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Louisiana

COVID-19 status

Confirmed
Outcome

Hospitalization
Treatment

Antihypertensive, Antihypertensive + Nutrition, SOC
Trial Participants

1080

Louisiana

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, Bilirubin
Treatment

Remdesivir
Trial Participants

52

Louisiana

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ, SOC
Trial Participants

479

Louisiana

COVID-19 status

NA
Outcome

Labor Absenteeism
Treatment

HCQ, SOC
Trial Participants

1700

Louisiana

COVID-19 status

Confirmed
Outcome

Mortality, Organ Failure or Dysfunction (SOFA), Serious Adverse Events, Antibodies
Treatment

Remdesivir, Remdesivir + Other
Trial Participants

10000

Louisiana

COVID-19 status

Healthy
Outcome

Visits or Returns to Emergency Department, Antibodies
Treatment

SOC, Vaccine
Trial Participants

40051

Louisiana

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, White Blood Cell Count, Monocyte Count, Lymphocyte Count, Neutrophils, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, SOC
Trial Participants

1062

Louisiana

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Serious Adverse Events
Treatment

Monoclonal antibody, SOC
Trial Participants

1360

Louisiana

COVID-19 status

Healthy
Outcome

Mortality, ICU Admission, Hospital Discharge, Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea
Treatment

Plasma based therapy, SOC
Trial Participants

500

Louisiana

COVID-19 status

NA
Outcome

Clinical Improvement Score (Any), Viral Load or Clearance, Adverse Events
Treatment

HCQ, HCQ + AZT, SOC
Trial Participants

20

Louisiana

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Non-invasive Ventilation, Treatment-emergent Adverse Events
Treatment

Remdesivir, SOC
Trial Participants

1113

Louisiana

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, C-Reactive Protein, IL-6, White Blood Cell Count, Platelet Count, Hemoglobin, ALT, AST, Bilirubin, Respiratory Rate, Hypoxemia
Treatment

Sarilumab, SOC
Trial Participants

1912

Louisiana

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Serious Adverse Events, Antibodies
Treatment

Plasma based therapy, SOC
Trial Participants

1344

Louisiana

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, INR, ALT, AST, Bilirubin
Treatment

Remdesivir, Remdesivir + IFN
Trial Participants

969

Louisiana

COVID-19 status

NA
Outcome

NA
Treatment

Plasma based therapy
Trial Participants

NA

Louisiana

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, ALT, Bilirubin
Treatment

mAb, SOC
Trial Participants

270

Louisiana

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Organ Failure or Dysfunction (SOFA), Adverse Events
Treatment

JAKi, SOC
Trial Participants

500

Louisiana

COVID-19 status

NA
Outcome

NA
Treatment

HCQ, HCQ + AZT, SOC
Trial Participants

600

Lucerne

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), C-Reactive Protein, Hemoglobin, D-Dimer, eGFR, Glucose, Renal Outcome (Unspecified)
Treatment

mAb, SOC
Trial Participants

116

Lusaka

COVID-19 status

Healthy
Outcome

NA
Treatment

HCQ, SOC
Trial Participants

30000

Luxembourg

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Platelet Count, Hemoglobin, Prothrombin, Electrolytes, INR, ALT, AST, Bilirubin, Glucose
Treatment

HCQ, LPV/r, LPV/r + IFN, Remdesivir, SOC
Trial Participants

3100

Madhya Pradesh

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Non-invasive Ventilation, Organ Failure or Dysfunction (SOFA)
Treatment

Other, SOC
Trial Participants

40

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, C-Reactive Protein, Ferritin, Lymphocyte Count, SpO2
Treatment

Acalabrutinib, SOC
Trial Participants

177

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, PaO2-FiO2, Blood pH
Treatment

Colchicine, SOC
Trial Participants

6000

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, Ferritin, Lymphocyte Count, Platelet Count, Hemoglobin, D-Dimer, ALT, Bilirubin, LDH, SpO2, Hypoxemia
Treatment

Corticosteroids, Siltuximab
Trial Participants

200

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Organ Failure or Dysfunction (SOFA), Adverse Events, Distress
Treatment

HCQ, SOC
Trial Participants

NA

Madrid

COVID-19 status

NA
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Serious Adverse Events, Radiographic Findings
Treatment

HCQ + AZT or LPV/r + IFN, Plasma based therapy
Trial Participants

72

Madrid

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6
Treatment

Dexamethasone, SOC
Trial Participants

200

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Invasive Mechanical Ventilation or ECMO
Treatment

Melatonin, SOC
Trial Participants

NA

Madrid

COVID-19 status

Confirmed Or Suspected
Outcome

ICU Admission, Hospitalization, Clinical Improvement Score (Any), Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events
Treatment

JAKi + Statins, SOC
Trial Participants

94

Madrid

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Ferritin, IL-6, IL-10, IL-12, Lymphocyte Count, D-Dimer, Troponin
Treatment

Other, SOC
Trial Participants

NA

Madrid

COVID-19 status

Resolved
Outcome

NA
Treatment

Psychological therapy, SOC
Trial Participants

150

Madrid

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious Adverse Events, Respiratory Rate, Hypoxemia
Treatment

Sarilumab, SOC
Trial Participants

420

Madrid

COVID-19 status

NA
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Ferritin, Lymphocyte Count, Neutrophils
Treatment

Non-invasive respiratory support, SOC
Trial Participants

208

Madrid

COVID-19 status

NA
Outcome

Mortality, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Adverse Events, Treatment-emergent Adverse Events, C-Reactive Protein, IL-6, MCP-1, Dendritic Cell Count, D-Dimer, Coagulation Test, ALT, Glucose, LDH
Treatment

Plasma based therapy, SOC
Trial Participants

278

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Serious Adverse Events, C-Reactive Protein, Ferritin, Lymphocyte Count, PaO2-FiO2
Treatment

Acalabrutinib, SOC
Trial Participants

163

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Madrid

COVID-19 status

Confirmed
Outcome

Hospitalization, Adverse Events, C-Reactive Protein, Ferritin, D-Dimer, LDH, PaO2-FiO2
Treatment

Radiation therapy
Trial Participants

41

Madrid

COVID-19 status

Confirmed
Outcome

NA
Treatment

Natural Killer Cells, Other
Trial Participants

58

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Adverse Events, Radiographic Findings
Treatment

Other, SOC
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Treatment-emergent Adverse Events, ECG
Treatment

SOC, Trimodulin
Trial Participants

164

Madrid

COVID-19 status

Confirmed
Outcome

NA
Treatment

HCQ + LPV/r + TCZ + AZT + Corticosteroids + Anticoagulants + Non-invasive respiratory support, Radiation therapy + HCQ + LPV/r + TCZ + AZT + Corticosteroids + Anticoagulants + Non-invasive respiratory support
Trial Participants

106

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Antibodies, ECG, Hypoxemia
Treatment

Immunomodulators, mAb, SOC
Trial Participants

300

Madrid

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Adverse Events, C-Reactive Protein, D-Dimer, Troponin
Treatment

Other, SOC
Trial Participants

1034

Madrid

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Invasive Mechanical Ventilation or ECMO
Treatment

NA
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), SpO2
Treatment

mAb, SOC
Trial Participants

270

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Creatinine Phosphokinase, ALT, AST, Bilirubin, ECG
Treatment

Other
Trial Participants

46

Madrid

COVID-19 status

Healthy
Outcome

Mortality, Viral Load or Clearance
Treatment

NA
Trial Participants

NA

Madrid

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Organ Failure or Dysfunction (SOFA), Adverse Events, Serious Adverse Events
Treatment

NA
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospital Discharge, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Fever
Treatment

Igs
Trial Participants

100

Madrid

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

NA
Trial Participants

NA

Madrid

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Creatinine Phosphokinase, CK-MB, Troponin, Fibrinogen, ALT, AST, Bilirubin, Glucose, LDH
Treatment

TCZ
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Viral Load or Clearance, Pneumonia or ARDS, Fever, Adverse Events, Treatment-emergent Adverse Events, Ferritin, D-Dimer, LDH, PaO2-FiO2, Respiratory Rate
Treatment

NA
Trial Participants

NA

Madrid

COVID-19 status

NA
Outcome

Mortality, Non-invasive Ventilation, IL-1, IL-6, IL-8, Tumor Necrosis Factor (Any), PaO2-FiO2
Treatment

Anesthetic, SOC
Trial Participants

NA

Madrid

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Serious or Seconday Infections, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, Ferritin, White Blood Cell Count, Lymphocyte Count, Platelet Count, Hemoglobin, D-Dimer, ALT, Bilirubin, LDH, SpO2, Radiographic Findings, Hypoxemia, Renal Outcome (Unspecified)
Treatment

Corticosteroids, Siltuximab
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Treatment-emergent Adverse Events, Serious Adverse Events
Treatment

HCQ + Imatinib, HCQ + JAKi, HCQ + LPV/r
Trial Participants

165

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, C-Reactive Protein, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Prothrombin, ALT, AST, Bilirubin, Glucose
Treatment

Remdesivir, Remdesivir + JAKi
Trial Participants

1034

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events, White Blood Cell Count, Platelet Count, Hemoglobin, Prothrombin, ALT, AST, Bilirubin, Glucose, Renal Outcome (Unspecified)
Treatment

Remdesivir, SOC
Trial Participants

440

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, Viral Load or Clearance, Household Members with CoViD-19, Adverse Events, Hemoglobin, Weight, Height or BMI, Pregnancy or Birth Outcomes
Treatment

HCQ, SOC
Trial Participants

NA

Madrid

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever
Treatment

Sarilumab, SOC
Trial Participants

30

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Adverse Events, Renal Outcome (Unspecified)
Treatment

Igs, Plasma based therapy
Trial Participants

116

Madrid

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Other Mild Symptoms, IgG, IgM or IgA, Radiographic Findings, Distress
Treatment

Melatonin, SOC
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Labor Absenteeism, Fever, SpO2, Respiratory Rate
Treatment

Other, SOC
Trial Participants

230

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Distress
Treatment

Other, SOC
Trial Participants

100

Madrid

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Ferritin, IL-6, Lymphocyte Count, D-Dimer, Creatinine Phosphokinase, LDH, CD4, Blood Pressure, Renal Outcome (Unspecified)
Treatment

Cyclosporine, Darunavir, HCQ, IFN, LPV/r, Other, TCZ
Trial Participants

NA

Madrid

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospital Discharge, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Adverse Events, Ferritin, IL-1, IL-2, IL-6, IL-12, Tumor Necrosis Factor (Any), D-Dimer, Triglycerides, SpO2
Treatment

Cyclosporine, TCZ
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Labor Absenteeism, Pneumonia or ARDS, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Hyper-Inflammation, Serious or Seconday Infections, Organ Failure or Dysfunction (SOFA), Deep Vein Thrombosis or Pulmonary Embolism, Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-6, Tumor Necrosis Factor (Any), White Blood Cell Count, D-Dimer, Creatinine Phosphokinase, Bilirubin, Glucose, Antibodies, PaO2-FiO2, Radiographic Findings, Lung Inflamation, Hypoxemia, Quality of Life
Treatment

SOC, TCZ
Trial Participants

450

Madrid

COVID-19 status

Confirmed
Outcome

Treatment-emergent Adverse Events
Treatment

Remdesivir
Trial Participants

2500

Madrid

COVID-19 status

Confirmed
Outcome

Hospitalization, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1450

Madrid

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, IL-6, D-Dimer, Renal Outcome (Unspecified)
Treatment

AZT, HCQ, Sarilumab
Trial Participants

NA

Madrid

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Pneumonia or ARDS, Cough, Fever, Dyspnea, Other Mild Symptoms, Serious or Seconday Infections, Anti SARS-COV-2 Titers, Peak RC-Reactive Protein, Ferritin, IL-6, White Blood Cell Count, Lymphocyte Count, Neutrophils, Platelet Count, Hemoglobin, Erythrocyte Sedimentation Rate, D-Dimer, Creatinine Phosphokinase, Troponin, Procalcitonin, Fibrinogen, Coagulation Test, ALT, AST, Albumin, Bilirubin, LDH, PaO2-FiO2, SpO2, Respiratory Rate, Radiographic Findings, Shock
Treatment

HCQ, Imatinib, JAKi, LPV/r
Trial Participants

NA

Madrid

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever
Treatment

Sarilumab, SOC
Trial Participants

30

Madrid

COVID-19 status

NA
Outcome

Clinical Improvement Score (Any), Cough, Fever, Dyspnea, Other Mild Symptoms, Serious or Seconday Infections, Adverse Events
Treatment

HCQ
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission
Treatment

HCQ, SOC
Trial Participants

800

Madrid

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), C-Reactive Protein, Ferritin, IL-1, IL-6, Tumor Necrosis Factor (Any), D-Dimer, LDH
Treatment

Colchicine, SOC
Trial Participants

NA

Madrid

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Organ Failure or Dysfunction (SOFA), Adverse Events, C-Reactive Protein, IL-1, IL-2, IL-4, IL-6, IL-8, IL-10, Tumor Necrosis Factor (Any), White Blood Cell Count, Lymphocyte Count, Natural Killer Cell Count, Platelet Count, Hemoglobin, D-Dimer, Creatinine Phosphokinase, Procalcitonin, Prothrombin, Fibrinogen, Coagulation Test, Electrolytes, INR, ALT, AST, Bilirubin, Glucose, LDH, IgG, IgM or IgA, CD4, CD8, Blood Urea Nitrogen, PaO2-FiO2, SpO2, Radiographic Findings
Treatment

Stem cells
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ + AZT, TCZ + AZT + HCQ
Trial Participants

276

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Cough, Fever, Dyspnea, Other Mild Symptoms
Treatment

SOC, Vitamins
Trial Participants

200

Madrid

COVID-19 status

NA
Outcome

Viral Load or Clearance, Other Mild Symptoms
Treatment

HCQ
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

NA
Treatment

NA
Trial Participants

84

Madrid

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Organ Failure or Dysfunction (SOFA), C-Reactive Protein, Ferritin, White Blood Cell Count, Platelet Count, Hemoglobin, D-Dimer, Troponin, ALT, AST, LDH, Blood Urea Nitrogen, PaO2-FiO2, SpO2, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

Sarilumab
Trial Participants

NA

Madrid

COVID-19 status

NA
Outcome

Mortality, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Dyspnea, Other Mild Symptoms, Serious or Seconday Infections, Adverse Events, Ferritin, IL-6, D-Dimer, LDH, Blood Pressure, PaO2-FiO2, SpO2, Radiographic Findings
Treatment

Other
Trial Participants

NA

Madrid

COVID-19 status

NA
Outcome

Mortality, Invasive Mechanical Ventilation or ECMO, Other Mild Symptoms, Radiographic Findings
Treatment

SOC, Stem cells
Trial Participants

24

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Adverse Events, Serious Adverse Events
Treatment

mAb, SOC
Trial Participants

800

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

300

Madrid

COVID-19 status

NA
Outcome

Mortality, Adverse Events
Treatment

Antivirals, SOC
Trial Participants

1300

Madrid

COVID-19 status

Confirmed Or Suspected
Outcome

Mortality, ICU Admission, Clinical Improvement Score (Any), Pneumonia or ARDS, Non-invasive Ventilation, Adverse Events, ECG
Treatment

Antivirals, SOC
Trial Participants

200

Madrid

COVID-19 status

NA
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Adverse Events, C-Reactive Protein, IL-1, IL-6, IL-8, IL-10, IL-12, Tumor Necrosis Factor (Any), PAI-1, Interferon (Any), White Blood Cell Count, Neutrophils, Platelet Count, Hemoglobin, D-Dimer, ALT, AST, Bilirubin, Renal Outcome (Unspecified)
Treatment

Sarilumab, SOC
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Viral Load or Clearance, Labor Absenteeism, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Dyspnea, Adverse Events, IL-2, IL-4, IL-6, IL-8, IL-12, Tumor Necrosis Factor (Any), Interferon (Any), MIP-1, Respiratory Rate
Treatment

Vitamins
Trial Participants

NA

Madrid

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Organ Failure or Dysfunction (SOFA), Adverse Events, Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

ARBs, SOC
Trial Participants

1372

Madrid

COVID-19 status

NA
Outcome

Adverse Events, Anti SARS-COV-2 Titers
Treatment

HCQ, SOC
Trial Participants

NA

Madrid

COVID-19 status

NA
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Neutrophils
Treatment

Immunomodulators, SOC
Trial Participants

120

Madrid

COVID-19 status

NA
Outcome

ICU Admission, Hospitalization, Blood Gas, ECG, SpO2, Radiographic Findings
Treatment

Corticosteroids, SOC
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, Clinical Improvement Score (Any), Viral Load or Clearance, Adverse Events, Serious Adverse Events, ACE
Treatment

LPV/r + HCQ, Stem cells
Trial Participants

NA

Madrid

COVID-19 status

Healthy
Outcome

Viral Load or Clearance, Treatment-emergent Adverse Events, Serious Adverse Events
Treatment

HCQ, SOC
Trial Participants

440

Madrid

COVID-19 status

Confirmed
Outcome

NA
Treatment

Anticoagulants
Trial Participants

164

Madrid

COVID-19 status

Confirmed
Outcome

Adverse Events
Treatment

SOC, Stem cells
Trial Participants

100

Madrid

COVID-19 status

Healthy
Outcome

NA
Treatment

Other, SOC
Trial Participants

315

Madrid

COVID-19 status

Healthy
Outcome

ICU Admission, Pneumonia or ARDS, Cough, Fever, Other Mild Symptoms, ECG
Treatment

HCQ, SOC
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events
Treatment

Remdesivir
Trial Participants

52

Madrid

COVID-19 status

Confirmed
Outcome

Invasive Mechanical Ventilation or ECMO
Treatment

Acalabrutinib, SOC
Trial Participants

140

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Serious or Seconday Infections, Deep Vein Thrombosis or Pulmonary Embolism, Adverse Events, Treatment-emergent Adverse Events, Anti SARS-COV-2 Titers, White Blood Cell Count, Neutrophils, Platelet Count, Hemoglobin, ALT, AST, Bilirubin, PaO2-FiO2, SpO2, Radiographic Findings, Renal Outcome (Unspecified)
Treatment

mAb
Trial Participants

NA

Madrid

COVID-19 status

NA
Outcome

NA
Treatment

Sarilumab, SOC
Trial Participants

120

Madrid

COVID-19 status

NA
Outcome

ICU Admission
Treatment

Other
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, SpO2, Respiratory Rate
Treatment

JAKi, SOC
Trial Participants

1000

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Ferritin, IL-1, IL-6, Lymphocyte Count, Neutrophils, Platelet Count, D-Dimer, LDH, SpO2
Treatment

Other, SOC
Trial Participants

NA

Madrid

COVID-19 status

NA
Outcome

Mortality, IL-1, IL-6, IL-8, Tumor Necrosis Factor (Any), PaO2-FiO2
Treatment

Anesthetic
Trial Participants

50

Madrid

COVID-19 status

Confirmed
Outcome

NA
Treatment

mAb, Other, SOC
Trial Participants

390

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, SpO2
Treatment

Anakinra, AZT, HCQ, LPV/r
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

Other, SOC
Trial Participants

100

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, Ferritin, IL-6, D-Dimer, SpO2
Treatment

Corticosteroids, HCQ + TCZ + LPV/r
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Other Mild Symptoms, SpO2
Treatment

CCB, Other, SOC
Trial Participants

804

Madrid

COVID-19 status

Confirmed
Outcome

ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

Igs, SOC
Trial Participants

100

Madrid

COVID-19 status

Confirmed
Outcome

Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Invasive Mechanical Ventilation or ECMO, Treatment-emergent Adverse Events, Bilirubin
Treatment

Remdesivir
Trial Participants

52

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Adverse Events, Serious Adverse Events, C-Reactive Protein, Ferritin, IL-1, IL-6, IL-10, IL-12, IL-17, D-Dimer, Procalcitonin, PaO2-FiO2, SpO2, Radiographic Findings, Quality of Life
Treatment

SOC, TCZ
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, Hospitalization, Invasive Mechanical Ventilation or ECMO, SpO2, Respiratory Rate
Treatment

Anticoagulants
Trial Participants

NA

Madrid

COVID-19 status

Confirmed Or Healthy
Outcome

Mortality, Viral Load or Clearance, Household Members with CoViD-19, Anti SARS-COV-2 Titers
Treatment

Ivermectin, SOC
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, Hospital Discharge, Clinical Improvement Score (Any), Viral Load or Clearance, Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, Fever, Organ Failure or Dysfunction (SOFA), Adverse Events, Treatment-emergent Adverse Events, Serious Adverse Events, White Blood Cell Count, Lymphocyte Count, Platelet Count, Hemoglobin, Coagulation Test, ALT, AST, Albumin, Bilirubin, Glucose, SpO2, Radiographic Findings, Renal Outcome (Unspecified)
Treatment

SOC, TCZ + mAb
Trial Participants

24

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospital Discharge
Treatment

SOC, Vitamins
Trial Participants

NA

Madrid

COVID-19 status

NA
Outcome

Mortality, ICU Admission, Hospitalization, Viral Load or Clearance
Treatment

SOC, Vitamins
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

Hospitalization, Viral Load or Clearance, Non-invasive Ventilation, Cough, Fever, Dyspnea, Treatment-emergent Adverse Events, Respiratory Rate
Treatment

Other, SOC
Trial Participants

380

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, Viral Load or Clearance, Cough, Fever, Adverse Events, IgG, IgM or IgA
Treatment

Ivermectin, SOC
Trial Participants

NA

Madrid

COVID-19 status

NA
Outcome

Mortality, Hospitalization, Hospital Discharge, Visits or Returns to Emergency Department, Clinical Improvement Score (Any), Invasive Mechanical Ventilation or ECMO, Adverse Events, Antibodies
Treatment

Plasma based therapy, SOC
Trial Participants

60

Madrid

COVID-19 status

Confirmed
Outcome

Hospitalization, Invasive Mechanical Ventilation or ECMO, Adverse Events
Treatment

Colchicine, SOC
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

SpO2, Radiographic Findings
Treatment

Radiation therapy
Trial Participants

41

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events, SpO2
Treatment

JAKi, SOC
Trial Participants

402

Madrid

COVID-19 status

Healthy
Outcome

NA
Treatment

SOC, Vaccine
Trial Participants

315

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Invasive Mechanical Ventilation or ECMO
Treatment

HCQ, LPV/r, Remdesivir, SOC
Trial Participants

7000

Madrid

COVID-19 status

Healthy
Outcome

Viral Load or Clearance, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Adverse Events, Distress
Treatment

HCQ, SOC
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Clinical Improvement Score (Any), Viral Load or Clearance, Serious or Seconday Infections, Adverse Events, C-Reactive Protein, Ferritin, Monocyte Count, Lymphocyte Count, D-Dimer, CD4, CD8, Radiographic Findings
Treatment

Other, SOC
Trial Participants

200

Madrid

COVID-19 status

Confirmed
Outcome

Clinical Improvement Score (Any), Adverse Events
Treatment

Remdesivir
Trial Participants

4891

Madrid

COVID-19 status

NA
Outcome

Mortality
Treatment

SOC, Stem cells
Trial Participants

106

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Non-invasive Ventilation, Organ Failure or Dysfunction (SOFA), PaO2-FiO2, Shock
Treatment

Corticosteroids, SOC
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Adverse Events
Treatment

HCQ, HCQ + Cyclosporine
Trial Participants

NA

Madrid

COVID-19 status

Confirmed
Outcome

Hospitalization, Hospital Discharge, Clinical Improvement Score (Any), Non-invasive Ventilation, Invasive Mechanical Ventilation or ECMO, C-Reactive Protein, Quality of Life
Treatment

Other, SOC
Trial Participants

140

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Pneumonia or ARDS, Invasive Mechanical Ventilation or ECMO, Serious Adverse Events
Treatment

TCZ
Trial Participants

500

Madrid

COVID-19 status

Confirmed Or Suspected
Outcome

NA
Treatment

Other, SOC
Trial Participants

400

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, Organ Failure or Dysfunction (SOFA), Serious Adverse Events, Antibodies
Treatment

Remdesivir, Remdesivir + Other
Trial Participants

10000

Madrid

COVID-19 status

Confirmed
Outcome

Mortality, ICU Admission, Hospitalization, Hospital Discharge, Invasive Mechanical Ventilation or ECMO, Organ Failure or Dysfunction (SOFA), Renal Outcome (Unspecified), Cardiac Outcome (Unspecified)
Treatment

SGLT2, SOC
Trial Participants

900

Madrid

COVID-19 status

Confirmed
Outcome

Mortality
Treatment

SOC, Stem cells
Trial Participants

30

Madrid

COVID-19 status

NA
Outcome

ICU Admission, Invasive Mechanical Ventilation or ECMO
Treatment

JAKi, SOC
Trial Participants

Antibodies	80
Antivirals	32
Cell-Based Therapy	35
Device	10
DNA - Based	21
Inactivated Virus	18
Live Attenuated Virus	4
Non-Replicating Viral Vector	28
Protein Subunit	78
Replicating Bacterial Vector	2
Replicating viral vector	21
RNA- Based Treatments	6
RNA- Based Vaccine	29
Scanning Compounds to Repurpose	21
Virus Like Particle	20
Others	154
Final	559

1000	569	231	1800
1000	569	231	1800
1000	569	231	1800
1000	569	231	1800
1000	569	231	1800
1000	569	231	1800
1000	569	231	1800
1000	569	231	1800
1000	569	231	1800

What's Changed!

COVID-19 Vaccine and Treatment Tracker

Global Statistics What's Changed!

310

Pre-clinical

205

Clinical

13

Phase I

14

Phase I / II

3

Phase II

1

Phase II / III

11

Phase III

0

Approved

COVID-19 Vaccines Approved for Limited Use

NCT04437875

NCT04313127

NCT04352608

COVID-19 Vaccine & Treatment Statistics

Covid-19 Vaccine Trial Status

Phase Wise % and No. of Developers

Trial Stages

Product Category Wise Treatments

Treatment Trials Active or Dormant

COVID-19 Vaccines & Treatments (India)

3

0

2

1

1

0

Vaccine Tracker

Treatment Tracker

Abu Dhabi

Abu Dhabi

Abu Dhabi

Abu Dhabi

Accra

Accra

Accra

Accra

Adana

Addis Ababa

Afyonkarahisar

Aguascalientes

Aichi

Aichi

Aichi

Al Iskandariyah

Al Madinah

Alabama

Alabama

Alabama

Alabama

Alabama

Alabama

Alabama

Alabama

Alabama

Alabama

Alabama

Alabama

Alabama

Alabama

Alabama

Alabama

Alabama

Alabama

Alabama

Alabama

Alabama

Alabama

Alabama

Alabama

Alabama